Never Again Shall We Submit

30s | Latina | Demisexual | Huge nerd posting whatever I like | Currently reading: A Crown of Swords

[magemance]

"How do you do it?" "There's not really a choice."

[wibblyrlin]

THE WOMEN OF THE WHEEL OF TIME + channeling

[blumineck]

How to spring-load your bow!

This information is freely given. What you do with it is up to you! 🏹💐🧚🏼

[wyllravengards]

Nightingale's Eyes

Southeast Asian Leliana inspired by a post I saw that I sadly lost >.> If anyone knows the post I'm talking about pls share!!

Also please reblog if you like it, I spent all day painting and now my hands hurt so I'd really appreciate some likes and reblogs <3

[whyvern-art]

a brilliant exchange

[jadeandquartzes]

[id: close up art of vaelus and tyranny's faces. vaelus looks at tyranny intently and says "a freshly newborn baby" and tyranny points at vaelus with her tongue out and says "an old woman." end id.]

[maureen2musings]

212._.film

[uwillneverknowwho]

Literally always take headphones with you. If you decide that you probably won't need them today, that's the devil talking. You will. You will

[nocturnexc]

[miyku]

TOMB RAIDER Legacy of Atlantis | ▶ dev. Crystal Dynamics ˣ Flying Wild Hog

[annemarieyeretzian]

azune’s face as gus says “I’m not the wife-taking type.”,,, I am YELLING

[solidsmax]

God of War: Laufey dev. Santa Monica

[hanpaopaoo]

Environment study but for some reason I wanted to paint Amaterasu too

[aropride]

please god let chatgpt die out like nfts did. With a fast and graceless fall into irrelevancy

[bladespark]

Like to charge, reblog to cast.

[atwotonedbird]

This spell has a very low hit ratio, so we need a lot of us to do it.

[pyrrhiccomedy]

we're heading towards some record setting humidity this summer so JUST A REMINDER that if you're in any way prone to migraines, this weather is great at triggering them! Be EXTREMELY diligent about staying hydrated if you're going out, EVEN TO AN AIR CONDITIONED SPACE, and ESPECIALLY if you are drinking any alcohol at all! even a single glass of wine or a cocktail! You will feel fine for an hour or two but then you will NOT FEEL FINE. If you have a headache that isn't responding to painkillers and it gets noticeably worse when you move or change elevations (sitting to standing, not like, going to the mountains) then drink a full glass of water and go lie down in a cool, quiet, dark room until it passes! DO NOT LOOK AT A SCREEN UNTIL THE DANGER HAS PASSED. I know you're bored but it could be so much worse!

[pyrrhiccomedy]

I see this is going around again! Happy Migraine Season everybody! Remember to keep a damp washcloth in your freezer so that if you feel the migraine coming on you can lay down and press it against your forehead and temples to give yourself a better chance of ducking it before it's too late!

[literary-potato]

Also a reminder that for some folks, big changes in air pressure can also be a migraine trigger. So if you’re in an area that, like mine, is having a lot of really wild temperature swings (ie multiple very hot days that end abruptly with storms at which point it cools down a lot), might be a good idea to have your migraine remedies locked and loaded, because with migraines the sooner you intervene, the more likely it is you’ll avert the worst symptoms (and will need less medication to do so).

[earlgraytay]

If cold doesn't work for your migraines/makes them worse, get a heat pack- either those instant hand warmers or, better, a bag with rice that you can stick in the microwave for a minute. Slap that puppy on your eye or your neck (specifically around your sternocleidomastoid muscle/that tendon in your neck that gets stiff) and wham, instant relief.

[capricorn-0mnikorn]

A discovery in the muscles of long COVID patients may explain exercise troubles

Long COVID patients can experience severe energy crashes after physical exertion. New research provides clear evidence that there's a biolog

Full Transcript at the link; 3-minute listen.

Quote:

By taking biopsies from long COVID patients before and after exercising, scientists in the Netherlands constructed a startling picture of widespread abnormalities in muscle tissue that may explain this severe reaction to physical activity.

Among the most striking findings were clear signs that the cellular power plants, the mitochondria, are compromised and the tissue starved for energy.

"We saw this immediately and it's very profound," says Braeden Charlton, one of the study's authors at Vrije University in Amsterdam.

The tissue samples from long COVID patients also revealed severe muscle damage, a disturbed immune response, and a buildup of microclots.

"This is a very real disease," says Charlton. "We see this at basically every parameter that we measure."

[thatdiabolicalfeminist]

I feel insane seeing stuff like this because this research already exists for Myalgic Encephalomyelitis, a post viral condition caused by multiple types of viral infections that a LOT of people with "Long Covid" meet the diagnostic criteria for.

This article mentions that ME/CFS is a "similar complex condition" but that's DEEPLY underreporting the similarities. The phrase "post exertional malaise" (now researchers are trying to replace it but this article uses that phrase) was INVENTED for ME/CFS. It's the only known condition, before "long covid", that causes these kinds of symptoms after exertion!

It's good to know for sure that it's the same mechanisms at play when the inciting viral infection is Covid and not, for instance, Epstein-Barr or RSV, but half the time it doesn't seem like researchers are making comparisons at all, just reinventing the wheel and acting like "long covid" is a totally new phenomenon with no previous point of comparison. There are literally drugs in human trials to try to treat the mitochondrial dysfunction in ME, this dysfunction is well-established and fairly well understood and I feel insane when ppl report on long covid without mentioning that there is already a named and studied condition that accounts for this subset of symptoms!!

SOME researchers are drawing comparisons but they're largely ME researchers who everyone else is largely cignoring because of the widespread perception that ME is a fake disease for lazy women.

That same perception btw is why "graded exercise therapy" (GET), or exercise gradually increasing in intensity, cwas for years the go-to treatment despite MOUNTAINS of evidence that it makes ME patients sicker. Some end up permanently bedbound and unable to even eat or drink without a feeding tube/IV because the damage is so bad! The GET recommendation was finally changed only in the past few years in the US and the UK, and many doctors hate that they're not allowed to recommend it anymore, because they insist despite the evidence that ME/CFS is psychological and ME patients are just "deconditioned" and too lazy to do anything about it.

Now the same kind of "treatment" is being recommended for long covid patients despite evidence showing exercise is having the same kinds of cellular effects as it does in ME patients. "Taking PEM into account" sounds gentler but I'm deeply concerned about the reinvention of GET for patients who meet all the criteria for an illness that's been shown definitively to become permanently worse with GET. This mitochondrial damage is progressive in ME, and there's no reason to believe patients who meet all the criteria of ME after Covid won't experience the same progression if they force themselves past their energy envelope in such a systematic way.

The additional finding that T cells — part of the immune system's arsenal — had infiltrated the muscles of long COVID patients also caught Iwasaki's attention, possibly indicating "an autoimmune response within the muscle cells."

This autoimmune response is well-researched for ME. Every time you overexert, you're injuring your cells more and more. It's deeply worrying that rebranded GET is being recommended for long covid patients who meet the criteria for ME when research like this study keeps showing it's the same phenomenon.

[maxbegone]

GOD OF WAR: LAUFEY (dev. Santa Monica Studios)

[gigew]

CLAIR OBSCUR: EXPEDITION 33