Look it updated this stuff

Making this an art/personal blog. Figuring life out.

[rocketbirdie]

first ten minutes of professor layton and the unwound future

Visit Original Link

[lost-lycaon]

Scrub hare, De Hoop Nature Reserve

[feminist-space]

[tall]

[oblivionloading]

Oh shit. He’s dead-dead.

[trashywitchy]

I think you guys will love this gif I've made.

[petapeta]

[fironna-dragonsong]

[rimonoroni2]

i think we should be talking about the semi-recent advancements in cystic fibrosis treatment like all the time every day. there hasn’t been a drug like this since AZT medications for HIV infection it is truly fucking miraculous and very important

[rimonoroni2]

basically: cystic fibrosis is a genetic disease which makes the mucous a person generates extra sticky. it used to kill people in infancy, then with advancements in medical tech it killed people in young childhood, and until very recently cystic fibrosis patients could expect to live until about thirty years old with consistent painful lung infections and complications.

in 2019 the FDA approved a drug called trikafta (which is really three drugs in one) for cystic fibrosis treatment. what it essentially does is patch up the malfunctioning proteins that cause the extra sticky mucus. trikafta is effective on about 90% of cystic fibrosis patients.

people who had spent their entire lives in and out of hospitals, on and off of ventilators, suffering from pneumonia and sometimes treated through painful procedures like intubation took this drug, got out of bed, coughed up an entire lifetimes worth of mucus out of their lungs over the course of a few hours, breathed clearly for perhaps the first time in their lives, and now go on to live well into their seventies.

like isn’t that insane. isn’t that amazing. doesn’t that give you hope for the future of medical advancements and treatment. fuck. i think about it all the time……

[kittydesade]

There’s a WHAT.

For WHAT.

[sweetdreamspootypie]

It's been amazing!

My ward is the respiratory ward - CF is one of the things we specialize in.

Since this med came out we haven't had a SINGLE CF admission to the ward

There used to always be a CF patient spending a couple of months with us at a time

There's a man who is 23 years old who I was sure would not survive his next admission (aim saturations 85% is end stage lung disease)

There's a set of the local frequent flyers that we all know so well

Except

No we don't

On the CF specialist ward (with reasonable staff turnover)

Half the staff have probably never even seen a CF patient

They are going to live

[anartificialsatellite]

For the people asking "well how do we know people are living that long if it's so new????" Here's a page from the CF foundation about life expectancy.

Additionally, it should be noted that metrics like life expectancy are in no way a guarantee of... Anything. There are significant outlier CF patients who are at an advanced age now despite the odds due to a variety of different factors, having lived the majority of their lives before the development of modulators.

But the fact remains that the odds are better now than they have ever ever been before, by leaps and bounds. It isn't cured, and many patients still need significant treatment in addition to Trikafta, but it is so much better than anyone could have dreamed of twenty years ago, and that is a triumph.

[kittyoverlord]

Yes! My sister has a serious form of cf and finally is living a more comfortable and active life. She was also part of many of the clinical trials leading to these breakthroughs due to the nature of her cf. It's been very exciting to see.

[naamahdarling]

That's absolutely incredible. Don't get me wrong. It's miraculous from a clinical standpoint. But, uhh. Not to be a downer but I need people to see this so they stay angry and stay real about what medical breakthroughs actually mean for patients. When I call something "survival gatekeeping", this is what I mean:

That is per month with the most common coupon people are likely to use.

But don't worry, there's grants and patient assistance programs you can apply for. 🤞🫠 Most people in high income countries like the USA can get it "covered" through insurance for fewer thousands of dollars. Or even less if your insurance is good or the manufacturer likes how poor and/or on Medicaid you are! A good social worker will help you with the process, and make sure your yearly reapplications and PAs are done a little early so they have time to think about it before you run out. Jesus Christ.

NEVER look at something like this and navigate away feeling better about things without asking how much it costs and who can get it. NEVER. It isn't revolutionary until poor people can access it without a struggle.

[calebwittebane]

ok everyone time to start laying eggs

[the-frightening-ghoul]

‎

[calebwittebane]

time to start laying eggs, frightening ghoul

[the-frightening-ghoul]

‎

[the-frightening-ghoul-jr]

‎

[calebwittebane]

this is how blogging can have a huge impact on the lives of people and ghouls

[ufo-encounter]

*flies past*

[ufo-encounter-jr]

* ᶠˡᶦᵉˢ ᵖᵃˢᵗ*

[ufo-encounter]

?????

[gailynovelry]

The fastest way to accomplish The Project is to cease being afraid of The Project. The Project cannot maim you. The Project cannot kill you. The Project is more afraid of you than you are of it. It is okay if The Project turns out differently from how it was in your head, and it is okay if it has flaws. You are capable of engaging with The Project.

[mossworm]

one billion likes and I'll make my actual retired detective dad who tracked the actual mafia in actual fedora times critique the cartoon noir detective stuff in fallout 4

[ampervadasz]

[h-nry]

[mimosa-sex-tea-people-contrsf]

Buddy is like how the fuck did you get a picture of me

[theprofessional-amateur]

link to bluesky post

[theprofessional-amateur]

In addition to how to turn various things, it includes:

Other useful AI Removal/Detection links

How to spot AI Hallucinations like a Reference Librarian (originally on Substack)

Library Freedom Project has a lot of handouts about AI on their Resources page

[oatmealaddiction]

So I've seen the post going around that's kind of like "kids should be able to read whatever they want and not have their choices censored by adults" and I largely agree with one caveat which is that children need to be able to opt in. I remember being 12 and sneaking some dirty books, and being interested and excited to read a book with something more sexy in it, and no one died, and everything was fine, and I was not forever scarred. However I do remember being shown a a horror film at seven by a babysitter and not being able to sleep for three weeks, and if I'd known how scary the movie was I wouldn't have wanted to watch it.

Kids can usually know what they can handle. Kids cover their eyes at scary points in films, kids read past stuff they aren't ready for. But it is good to be clear like "Oh that book might have some scary parts you might not like, are you sure you want to get that one?" Or "Oh this book has some grown up things in them that you might have a hard time understanding, I want to check that your okay with that." Like give kids the warnings and options and they will probably make a safe and informed decision. It doesn't have to be either or.

[helloiamacashier]

I also think kids should be allowed to be wrong about what they can handle without getting in trouble for it. They should be able to go to the adults in their life and ask for help processing what they saw or read without fear of judgement or punishment.

[liveandletrain]

And kids (and anyone) should be allowed to change their minds at any point.

[josilverdragon]

"The horrors persist but so do libraries, books, iced coffee, sunsets, trees, the word 'fuck', the moon and the sea."

[danndesigns]

[violet-hady]

Okay, I am really obsessed with this joke. I literally reblog it every time I see it.

[imb0ring]

I would too ngl

[dubiousculturalartifact]

The new Odyssey adaptation has inevitably gotten people talking about a Muppet version of it, and they’re frequently suggesting Kermit as Odysseus, Miss Piggy as Penelope.

I’m sorry but that’s thinking way too small, hear me out:

We need to have Miss Piggy as Odysseus, and Kermit as Penelope.

Think about it… who’s the more fickle, prideful, warlike one in that relationship? Who is absolutely ready to go ham, at a moment’s notice?

It ain’t Kermit