When did Orryx tell Astarion about his family, and how did Astarion respond? Love, love, LOVE your art!
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As for that question hooo boy that's a doozy.
Orryx follows the typical durge storyline when it comes to the amnesia. Throughout the beginning of his relationship to Astarion, he wouldn't know he had a wife or child in the past to begin with.
He does own a locket (which belonged to his wife before him).
When Aramit is killed, Orryx takes the locket and keeps a picture of her and their son in there.
All these years later, he'd still have that locket, albeit the pictures are faded. He would be able to figure out this woman and child meant SOMETHING to him for him to carry the locket with him. He assumes either its an image of him and his mother (his kid looks like a young version of Orryx) or his wife and child.
He concludes wife and child as the answer when he has a dream about sleeping with Aramit the night after he first sleeps with Astarion. And almost like she's really haunting him, she teases him for his reactions to her despite not remembering her name.
But that's something he struggles with silently for the rest of Act 1, simply because he has no confirmation. Only a hunch.
Now we get to Act 2. This is where his memory storyline differs from the original durge a bit.
When they attack Moonrise, and find the Chosen of the Dead Three in its bowels, everything comes rushing back. It's all of those emotions on top of nearly losing Astarion in the fight against Myrkul that cause Orryx to transform for the only time into the Slayer, finishing out the fight.
By this point, Astarion and he have a much closer relationship. Astarion has confided in him and trusted him with a lot, and he feels safe enough to do the same. They sit down and talk about it that night after they take Moonrise and kill Ketheric.
Astarion's first reaction is, of course, how this is going to affect Astarion. Will this random woman and kid affect his relationship? Orryx is married to her, and surely, if he's the man Astarion has come to know, he would choose his wife over a vampire he just met this year? He's already plotting how to move from here, pushing oh-so-valiantly past the idea of sabotage, until Orryx gets to the next part of his tale.
The part where he murdered, nay, slaughtered his own wife and child. 20 odd years ago.
Astarion is quiet in mind and mouth after that.
Orryx has already attacked him in his sleep once, so they know about the Urges. Even moreso with Orryx's returned memory. And Astarion leans into that. He says softly that Orryx was nearly chewing his own wrists off to try and kill Astarion after only a few weeks of repressed urges, he cannot imagine what a decade and a half of repressed Urges would do.
Astarion would tell him that yes, Orryx is a danger to him. He'd be stupid to deny that. But if he can be forgiven for the thousands of people he lured to the slaughter under Cazador, then Orryx can be forgiven for the murders he committed under the Urges.
Orryx stays in Astarion's tent that night, just to be close to him, and shows him the locket for the first time. The woman staring back at Astarion has a passing familiarity, but he keeps that to himself, and simply comments that she's beautiful, and clearly Orryx has a type.
He also comments that he knows Orryx was a good husband and father, simply because of how he is with Astarion himself, and with every tiefling kid they've run into.
Privately, though, Astarion does worry for his own life. He worries that Orryx is a much more noble man than he originally thought, and that eventually he'll wisen up and leave Astarion in the dirt.
He shoves those thoughts down by spending the rest of the night asking about Orryx's son, and what he was like. When his family becomes too emotional of a topic, he switches to asking about Orryx's life story, now that he remembers it.
If there's one thing Astarion knows how to do, it's talk. And talk he does, until they've talked for so long that he's lulled his beastly partner into sleep.
Until he's alone in his thoughts, finally able to understand and meditate on the weight of Orryx having lost his family. For a while, he'll focus on how he needs Orryx to overcome that. For both their sakes.
Full real empathy will come later.