Thought that just came to me:
Genesis and Lucrecia would either dislike each other at once or get on famously.
They have so much in common! Lucrecia’s thesis abstract has overwrought religious poetry! They are very similar flavors of nerd, although I’m fairly sure Genesis wouldn’t understand Lucrecia’s work, since Shalua couldn’t get through it and Genesis doesn’t have a sciences background.
But they both care a lot about appearances. They’re both schemers. (With records of being not-great about respecting the bodily autonomy of others.) They both like red. They both brood endlessly.
Genesis starts out by lashing out in every direction, both because he has more to be mad about and because violence is the most ego-syntonic option available to him, while Lucrecia is conscious primarily of her shame and clearly working through a whole heap of learned helplessness, but they both wind up sealing themselves arbitrarily away underground while the world goes to hell outside, and they supposedly feel real bad about their contributions to that but they aren’t doing shit.
It’s one of those cases where they’re just similar enough that depending on how their priorities align, or fail to, they are either going to fucking click which is terrifying, or be among one another’s least favorite people ever.
Bonus: there is technically no reason this encounter could not happen in the future of canon. Neither party is deceased.