#cdp-choline

[amcrasto]

CITICOLINE

CITICOLINE CDP-choline Molecular FormulaC14H26N4O11P2Average mass488.324 Da 5′-O-[Hydroxy({[2-(trimethylammonio)ethoxy]phosphinato}oxy)phosphoryl]cytidine987-78-0[RN]1-{5-O-[({Hydroxy[2-(trimethylammonio)ethoxy]phosphoryl}oxy)phosphinato]-β-D-ribofuranosyl}-4-imino-1,4-dihydro-2-pyrimidinol213-580-7[EINECS], 22902-Pyrimidinol,…

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[nootropicszone]

What Is The Best Choline Source?

Acetylcholine is a neurotransmitter known to play a role in memory, movement, and learning. It is one of a few key neurotransmitters that nootropics commonly affect. Some nootropics change the way acetylcholine works in the brain, while others increase acetylcholine levels. In this post, we're going to be comparing nootropics that increase acetylcholine levels. The nootropics

[nootropicszone]

CDP-Choline is a cholinergic nootropic that can be used by itself or as part of a nootropic stack. Click to learn all about this interesting nootropic.

[nootropicsamerica-blog]

CDP-Choline  

CDP-Choline is an active compound in nootropic substances. It stimulates the cholinergic neurotransmitter system by dissociating into choline and cytidine (which subsequently converts into uridine). This chemical compound is particularly beneficial when administered to the elderly, because its neuroprotective qualities help with memory impairments associated with aging. It is also a great option…

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[physicianformulas]

My Personal Experimentation With CDP-Choline supplement

CDP-choline stands for cytidine 5-diphosphocholine, an intermediate in the biosynthesis of membrane phospholipids and brain acetylcholine. I started one morning with a 250 mg pill. Within two hours I was more alert and focused with a slightly enhanced vision. The next day I took 500 mg and noticed even more alertness and focus, with a slight vision enhancement and perhaps a slight erectile enhancement. There was a mild improvement in mood. The side effects were increased body temperature and a little bit of underarm sweating. I like CDP-choline and I take it once in a while for a quick mental enhancement. The increased concentration and focus last several hours and then fade away. I also like Mind Power Rx a lot. If you wish, you can alternate CDP-choline one day and Mind Power Rx another day. For more info, see http://www.raysahelian.com/cdp.html.

[citrus-underground]

CDP-choline and Choline alphoscerate

"Attempts have been made to treat dementia and cognitive impairment with choline supplements such as lecithin (dietary PC, typically derived from eggs or soy), but a review of all unconfounded, randomized trials comparing lecithin with placebo revealed no particular benefit. Alternatives to choline or lecithin proposed to reverse age-related cognitive decline, were cytidine-diphosphocholine (CDP-choline) and choline alphoscerate (L-alpha-glyceryl-phosphorylcholine). Both are natural, water-soluble compounds providing comparable effects in different conditions. After oral administration, both CDP-choline and choline alphoscerate have been shown to cross the blood–brain barrier and reach the central nervous system ..."

"CDP-choline supplementation activates the synthesis of structural phospholipids in neuronal membranes, increases cerebral metabolism and to enhances various neurotransmitter systems. Clinical studies have documented its effectiveness in mild cognitive impairment, and in the management of Parkinson's disease.  Choline alphoscerate is probably, among choline-containing phospholipids, the most effective in enhancing in vivo ACh release and was also investigated with positive results on cognitive domain in patients affected by AD, cerebrovascular disorders and vascular dementia ..."

Reference

Tayebati, S. K., Tomassoni, D., Di Stefano, A., Sozio, P., Cerasa, L. S., & Amenta, F. (2011). Effect of choline-containing phospholipids on brain cholinergic transporters in the rat. Journal of the Neurological Sciences, 302(1–2), 49-57. doi:10.1016/j.jns.2010.11.028