Just finished reading The Amazing Spider-Man #38, and met what is probably one of the least known villains in the roster.
Joe Smith was once a mild mannered man with dreams to become a champion boxer. The only problem was that he sucked at boxing, so instead he decided to become champion wrestler, but he sucked at wrestling.
Then, one day, his manager gets him a gig as the monster in an upcoming sci-fi film.
However, while filming a scene, he knocks over a light into some chemicals and comic book science ensues.
After awaking, he loses control, going berserk and gaining super strength. Of course, Spidey comes in to stop him.
The day is eventually saved when the chemicals wear off, letting Joe Smith return to normal, and even get signed on with the studio for his realistic fighting. It’s actually kind of a sweet ending.