By Vassil - Own work, CC0, https://commons.wikimedia.org/w/index.php?curid=53806596
Senenmut, whose name means 'brother of mother', was born to a literate, provincial, commoner family. His parents, Ramose and Hatnofer who were from Inuy (modern day Armant), one of six children, two girls and four boys, all of whom are named are named in his tomb and he oversaw the building of his parents' tomb and it was found intact in the mid-1930s. Because he is portrayed alone or with his parents and one of his brothers was in charge of his funerary rites, it's thought he never married.
By User:Captmondo (Own work (photo)), CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=4624491
Senenmut was first mentioned being 'Steward of God's Wife', Hatshepsut, and 'Steward of the King's Daughter', that being Neferure, though it's unclear when he entered royal service. After Hatshepsut was crowned, he became the high steward. He supervised many building projects, including the obelisks that flanked the entrance to the Temple of Karnak, as well as Hatshepsut's buildings in Deir el-Bahri, including being chief architect of Djeser-Djeseru, Hatshepsut's Mortuary Temple.
By Diego Delso, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=122648660
The Djeser-Djeseru, or 'Sublime of the Sublimes' or 'Holy of Holiests', a 'colonnaded structure of perfect harmony built nearly one thousand years before the Parthenon' in about 1459 BCE. It is built into a cliff on the west side of the Nile, close to the Valley of the Kings, and opposite Luxor. It has three massive terraces and was built between Hatshepsut's seventh and twentieth regnal years. It takes heavy inspiration from the nearby Temple of Mentuhotep II, built about 600 years prior. It holds shrines to Hathor and Anubis, as well as reliefs that tell of the expedition to the Land of Punt. During the reign of Thutmose III, though, references to Hatshepsut were removed. It was again damaged under the reign of Akhenaten, who ordered the removal of any gods other than Aten, especially Amun, from temples. Repairs were begun under Tutankhamun. A later earthquake damaged the temple during the Third Intermediate Period (from about 1077-664 BCE).
By NebMaatRa - Own work, GPL, https://commons.wikimedia.org/w/index.php?curid=4441794
Senenmut began his own tomb, a hypogeum, or underground tomb, was started just before Hatshepsut took the throne. Within it is one of the oldest known astronomical ceilings. It is divided into two sections, 'representing the northern and southern skies'. This representation leads some researchers to believe he was also an astronomer. It's not known where Senenmut is buried, though he had a tomb built within his hypogeum, near Hatshepsut's, though it was also vandalized during the reign of Thutmose III, though his tomb was incomplete, which is unexpected for a high ranking noble.
By Keith Schengili-Roberts - Own work (photo), CC BY-SA 2.5, https://commons.wikimedia.org/w/index.php?curid=1625449
There are theories that Senenmut was Hatshepsut's lover based on the fact that his name and image were within Djeser-Djeseru, something rather intimate. There was also graffiti in an unfinished tomb depicting a hermaphrodite, likely representing Hatshepsut, having sex with a male, likely Senenmut. It also could be why Senenmut rose to such prominence and had a tomb so close to Hatshepsut's.