albert wesker joins many of my f/os in bisexual land. i'm a predictable man
i honestly see him as aroacespec pre-re1 because i think it takes him a while to find someone he views as an equal but then he'll try his best (to varying levels of success) to show his version of admiration. by the time re5 rolls around it's less full aroaceism and more he's still the same level of aroacespec and just willingly choosing to never bond to another mortal being (because he sees himself akin to a god and doesn't bother with petty affections. he thinks this and then still has a secret weak spot for the few people he latched onto prior to arklay)
he's a cis guy in my headcanon (he/him) but i think trans man wesker also would be funny bc i don't think he got bottom surgery. it's just that his superior intellect made him spontaneously impregnate a woman he met in the early 90s when stationed overseas /lh
also i polyship albert with excella so i'll quickly mention she's also bisexual in my hc. i know for sure she's a woman (she/her) but she could be either trans or cis. i don't really lean one way or another. she's just a pretty lady and that's all that matters to me :)