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'There are two blood proteins that could hold the key to a long, healthy life' 

Dr. Miriam Stoppard discusses a discovery that may aid in our understanding of the aging process and how key proteins may help us live longer, healthier lives. Could the answers be found in proteins in the blood?

I've been following ageing research that aims to slow down the aging process for years. So, how close are we to achieving the Holy Grail of medicine? We might be, according to research from Edinburgh University into which proteins influence how we age.

Scientists have discovered two blood proteins that affect how long and healthy a life we will live in the largest genetic study of ageing ever conducted. Their goal is to create drugs that target these proteins in order to slow the entire process down. From the time we reach adulthood, our bodies begin to deteriorate, resulting in age-related diseases and, eventually, death.

Genetics, lifestyle, environment, and chance all play a role in how quickly we age and die. The role of proteins (genetics) in this process is revealed in this study. Is it possible to slow down the aging process? These levels are determined by the DNA we inherit from our parents, and they have an impact on our health.

The findings of six large genetic studies on aging involving hundreds of thousands of people were combined by scientists. They looked at 857 proteins and found two that had significant negative effects on aging.

People who inherited DNA that causes elevated levels of these proteins, for example, were frailer, had worse self-reported health, and were less likely to live an exceptionally long life than those who did not.

So, what are the functions of these proteins? The first is LPA, which is produced in the liver and is thought to aid in blood clotting. LPA levels above a certain threshold can increase the risk of artery hardening, which can lead to heart disease and stroke.VCAM1, the second protein, is found on the inside of blood vessels and regulates their expansion and contraction during blood clotting and immune responses. When we have an infection, our levels of VCAM1 rise, which stimulates the immune system.

According to the researchers, drugs that lower LPA and VCAM1 levels may improve the quality and length of our lives. A clinical trial is already underway to see if lowering LPA can reduce the risk of heart disease, and early animal studies showed that VCAM1 improved cognition in the elderly.

"The discovery of these two key proteins could help people live longer and healthier lives," says Dr. Paul Timmers, lead researcher at Edinburgh University's MRC Human Genetics Unit.

"Drugs that lower these protein levels in our blood could allow the average person to live as healthy and as long as people who are born with low LPA and VCAM1 levels due to genetics."

What a brave new world!

( Photo by Nathan Cowley from Pexels )

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What You Can & Cannot Eat While On Keto Diet

For several years, the keto diet has been a fad. This diet, which was originally devised for epileptic patients, has gained widespread popularity as a weight loss plan because to its effectiveness in inducing quick weight loss. Yes, the keto diet (short for ketosis) was designed with epilepsy patients in mind. Fats account for 70-80% of a person's calorie intake in this case. Protein is consumed in moderate proportions, while carbs are consumed in little amounts. Rather than going on a calorie deficit, which is a prerequisite for weight loss, this diet demands balancing the three macronutrients. What foods can and cannot be eaten on a keto diet because fats provide the majority of calories and carbs are often avoided? Learn more....