Why am I doing this?

It had to happen eventually. Wish I could stop being so stupid. Header source: http://anglaisrose.co.vu/post/140904181656/commission-for-viscen-vas-arlesburgh-ive-always Permission was given before I used this piece

[pocketss]

it’s just one of those croissant days

[pocketss]

we love a recovery

[pocketss]

ha ha yeah

[pocketss]

noooo bro please wake up :(

[pocketss]

cricket finds compliments very alarming

[pocketss]

so hard to find a decent exorcist these days :/

[pocketss]

getting ready with the girrrlllss

part 1

[pocketss]

Mog is a good friend. Always there to offer words of advice, and sit uncomfortably close to you.

part 1 part 2

[pocketss]

mmm soob

[pocketss]

houseplant type friend

[mademoiseli]

The notes are broken. This is what tumblr is all about apparently.

[atonau]

THE NOTES ARE BROKEN!  This has been reblogged so many times, Tumblr just shrugged and said “infinity”

[wiki-but-made-them-up]

[astercrash]

[rimonoroni2]

i think we should be talking about the semi-recent advancements in cystic fibrosis treatment like all the time every day. there hasn’t been a drug like this since AZT medications for HIV infection it is truly fucking miraculous and very important

[rimonoroni2]

basically: cystic fibrosis is a genetic disease which makes the mucous a person generates extra sticky. it used to kill people in infancy, then with advancements in medical tech it killed people in young childhood, and until very recently cystic fibrosis patients could expect to live until about thirty years old with consistent painful lung infections and complications.

in 2019 the FDA approved a drug called trikafta (which is really three drugs in one) for cystic fibrosis treatment. what it essentially does is patch up the malfunctioning proteins that cause the extra sticky mucus. trikafta is effective on about 90% of cystic fibrosis patients.

people who had spent their entire lives in and out of hospitals, on and off of ventilators, suffering from pneumonia and sometimes treated through painful procedures like intubation took this drug, got out of bed, coughed up an entire lifetimes worth of mucus out of their lungs over the course of a few hours, breathed clearly for perhaps the first time in their lives, and now go on to live well into their seventies.

like isn’t that insane. isn’t that amazing. doesn’t that give you hope for the future of medical advancements and treatment. fuck. i think about it all the time……

[kittydesade]

There’s a WHAT.

For WHAT.

[sweetdreamspootypie]

It's been amazing!

My ward is the respiratory ward - CF is one of the things we specialize in.

Since this med came out we haven't had a SINGLE CF admission to the ward

There used to always be a CF patient spending a couple of months with us at a time

There's a man who is 23 years old who I was sure would not survive his next admission (aim saturations 85% is end stage lung disease)

There's a set of the local frequent flyers that we all know so well

Except

No we don't

On the CF specialist ward (with reasonable staff turnover)

Half the staff have probably never even seen a CF patient

They are going to live

[anartificialsatellite]

For the people asking "well how do we know people are living that long if it's so new????" Here's a page from the CF foundation about life expectancy.

Additionally, it should be noted that metrics like life expectancy are in no way a guarantee of... Anything. There are significant outlier CF patients who are at an advanced age now despite the odds due to a variety of different factors, having lived the majority of their lives before the development of modulators.

But the fact remains that the odds are better now than they have ever ever been before, by leaps and bounds. It isn't cured, and many patients still need significant treatment in addition to Trikafta, but it is so much better than anyone could have dreamed of twenty years ago, and that is a triumph.

[kittyoverlord]

Yes! My sister has a serious form of cf and finally is living a more comfortable and active life. She was also part of many of the clinical trials leading to these breakthroughs due to the nature of her cf. It's been very exciting to see.

[dandelionofthanatos]

SO YEAH HI LMAO I'm a CF patient who's presently taking Trikafta, and I have been since 2022. Before that, I was taking Kalydeco (ivacaftor), which is a component in Trikafta.

These medicines are incredible. My lung function's now basically at healthy-person-without-CF levels, and so's my sweat chloride. I still take pancreatic enzyme supplements, and I still do my respiratory treatments for maintenance reasons, but my overall health is still SO MUCH BETTER NOW. My weight is stable, I don't get anywhere near as many sinus infections, my migraines don't last as long.

Another incredibly cool thing is that they're seeing recovery from lung damage in kids who are on Trikafta and other CFTR modulators - and slight recovery in adults too. My own chest X-rays show that my bronchiectasis has gotten just a little better.

I was born in 1981, and it's wild to see how much the treatments and prognoses for CF patients have improved. Adult CF clinics are a thing now. More and more of us are living longer.

I'll always wish that more of my friends had made it this far, and gotten access to these medications. But I'm so grateful that I have this access, and I'll keep on keeping on in their memory.

[sailermoon]

this is how new yorkers @ mamdani

[sailermoon]

[excitedrainbow]

IT’S LITERALLY HAPPENING LMAOOOOO

[consulships]

i do think theres something sad about how largely only the literature that's considered especially good or important is intentionally preserved. i want to read stuff that ancient people thought sucked enormous balls

[literaryreference]

Time to take this post entirely too seriously:

I often wonder if this is why you so commonly see the sentiment that we are in an era of uniquely bad literature, or at least that the fact that most books don't have artistic aspirations and are not aiming to be anything other than mindless entertainment is new. In fact what's new is the idea that everything is worth preserving (and also the internet making it easier to preserve it). The dumb artistically unambitious trash books of the past have survived only sporadically, because people thought of them as literally disposable.

When I was in college I had a professor who was an expert on detective fiction. He had a longstanding beef with the idea that "Murders in the Rue Morgue" was the first detective story. He thought that it seemed way too polished to be inventing a new genre, and also that the whole orangutan business had the vibe of someone subverting preexisting audience expectations and maybe engaging in a bit of stealth parody. With the help of some student volunteers, he went trawling through old magazines and newspapers and found hundreds of detective stories from the early 1800s that just hadn't garnered enough individual attention to be remembered. This was because most of them sucked balls. He created an online archive of them, so you too can read these mostly terrible stories.

[tricky-pockets]

I've spent a ridiculous amount of time on Project Gutenberg sifting through forgotten old fiction and lemme tell ya. a lot of that stuff sucks ass.

[asteroidtroglodyte]

Tremendously comforting, really.

[dyk-tv-theme-song]

Do you recognize this TV theme song? #780

I know this and can name the series

I know this but can't name the series

I might know this

I've never heard this

Remaining time: 6 days 16 hours

[cheetahgirlmuscles]

Out of all the things I'm into, I think "people cumming" is honestly the funniest because of how basic it is. Like yeah I've got a fetish for enjoyable sex. My favorite thing to eat is tasty food. I really enjoy listening to good music. What are we even doing here where ami

[cheetahgirlmuscles]

You know what Mabel you're right. I gotta respect em. I DO like fun sex, I DO like tasty food, I DO like good music, and I DO like it when bad things happen to good people!

[udntnome]

no. you have to focus on schmovement

[martintheartizt]

FRACTURE - ILLUMINATE

Even in the darkest of times, your personality, thoughts and feelings will ALWAYS illuminate your way back to the light and humanity of reality once more... 💖