MC1R - Melanocortin 1 Receptor
This gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Gene mutations that lead to a loss in function are associated with increased pheomelanin (red pigment) production, which leads to lighter skin and hair color; on the other hand gain of function mutations cause melanism.
Northern and southern marsupial mole
Inheritence: fixed variant.
recessive yellow (two mutations)
tobacco darkening (from the tobacco mouse)
Inheritence: sombre and tobacco are dominant, yellow is recessive.
sombre and wild type (on nonagouti, but agouti sombres are also this dark), recessive yellow
Inheritence: intermediate.
Inheritence: both are recessive to the wild type, temporally codominant with each other: heterozygotes start out looking like recessive yellows and end up very close to fading yellow.
wild type (A/_ E/_), recessive yellow (A/_ e/e), black recessive yellow (a/a e/e), fading recessive yellow (_/_ ef/ef)
Inheritence: order of dominance is wild type (black) > bicolor > brown.
Inheritence: intermediate.
brown-black (Eb/E), jet-black (Eb/Eb)
Inheritence: wild type is dominant over red, otherwise everything is pretty much intermediate to varying degrees.
supersteel (EsEs), steel (black Ese, blue and black EsE), harlequinized chestnut (Eej), harlequin (ejej), "torted harlequin" (eje) [real torted harlequins are nonagoutis, this is agouti, so phenotypically harlequin], red (ee)
domino/grizzle/cocker sable (three mutations with similar effects)
recessive red(/yellow/cream/white) (three mutations)
Inheritence: order of dominance is melanistic mask > wild type > domino group > recessive red.
melanistic mask (on saddle tan), recessive red, domino, grizzle, cocker sable (all on black-and-tan)
white (two possible mutations, one is identical to one of the dog recessive red alleles)
Inheritence: intermediate.
silver (BB) with silver (BB) and cross (Bb) kits
winter-white (wild type), winter-brown
Inheritence: amber and russet are recessive to the wild type, carnelian is intermediate; their interactions are unknown.
amber (ea/ea), russet (er/er), copal (E/ec), carnelian (ec/ec)
Inheritence: intermediate.
dominant black (three mutations)
black spotting on red/white
Inheritence: order on dominance is black > wild type > black spots > red.
dominant black, red, black spotting
recessive red (three mutations)
Inheritence: order of dominance is dominant black>wild type>recessive red.
black and red (the white spotting is unrelated!)
Inheritence: very likely recessive.
imperial (black) nosed adult and native (gray) nosed young
dominant black (three mutations)
Inheritence: wow, i truly wonder.
black (the fleece often fades in adulthood), yellow spots (spots only because the breed is extensively white spotted)
dark belly (two mutations)
Inheritence: recessive to the wild type, intermediate with each other.
No image, for obvious reasons.
Horse, Przewalski's horse
domestic horse, Przewalski's horse
