Incredibly well put, thank you.
I have always struggled with call response, so i am not sure exactly how easy it will be to apply, but re-framing it as a medical thing is clever, its a clear paralell, and might be helpful as a mental referance point.
I generally struggle a lot with that "I acknowledge and share your emotion" side of things though. If someone told me "I've recently started med A for X problem, its working quite well." I struggle to find a responce between "that's nice", which people seem to find dismissive, and "Oh? I've heard good things about med B, you're not experiencing (common sympthom of A)?", which also doesn't seem to work, even if I remember to throw in a "Glad its working for you though!".
Spesifically applying the social framework around pregnancy is something I will have to reflect on. Certainly, no matter ones views, one would not get into the political side of pregnancies/child rearing, nor re-itterate that childlessness is a perfectly valid life path, if someone talks about their pregnancy. The same patterns fitting for transitioning makes intutive and logical sense, though its not quite a 1 to 1, as pregnancies are a predictable and "well established pipeline", freindly questions like "when are you due?" or "how long have you known?" are reasonable in almost every pregnancy, because, well, its predictable and knowable.
The same sort of questings don't quite make sense towards a transition, or when they do, they're more personal in a way. It's also more difficult to correctly identify in which situations a purely emotional responce is correct.
To referance back to the comic, there certainly are times when you can have a conversation with a trans person, as you indeed can with any person, about gender norms, and how we should lower barriers for women to act/present masculine, and for men to act/present feminine, and how that might look/be achived, and for me it can be challanging to sepperate those situations from the ones where a responce in that direction feels like the comics "there is nothing wrong with being feminine" (though I will note that my reflexive responce in that sitation would be almost the oppsite, something along the lines of 'not that there is anything wrong with a woman acting masculine', though I have no idea if that would be percived better or worse).
Nonetheless, asking myself 'are they telling me they're pregnant (metaphorically)' might be good question/approach to attempt to weave into my nattural patterns.
Once again thank you for your insight.