1. Dean Winchester and Castiel in Season 12, Episode 19: The Future, in a close-up of their hands nearly touching as Dean hands him back a cassette mixtape titled “Dean’s Top 13 Zepp Traxx”
2. Kaia Nieves and Claire Novak in Season 13, Episode 10: Wayward Sisters, a close-up of Kaia and Claire holding hands one last time in The Bad Place after Kaia is hit with AU!Kaia’s spear.
3. Sam Winchester and Rowena MacLeod in Season 15, Episode 3: The Rupture, a close-up of Sam and Rowena holding both of each other’s hands hands over a spell bowl.
4. Bobby Singer and Rufus Turner in Season 11, Episode 16: Safe House, a close-up of Bobby and Rufus almost holding hands after Rufus asks “You wanna hold my hand?”
5. Dean and Benny Lafitte in Season 8, Episode 19 Taxi Driver, holding hands in an alley, which turns into one last hug before Dean sends Benny back to Purgatory.
6. Sam and Castiel in Season 4, Episode 7 It’s the Great Pumpkin Sam Winchester!, meeting each other for the first time and greeting the other with a two-handed handshake as Castiel says Greetings Blood Freak “Sam Winchester, the boy with the demon blood.”
7. Dean and Crowley in Season 9, Episode 23: Do You Believe In Miracles? as Crowley places the First Blade into a (dead? dying?) Dean’s hands.
8. Sam and Ruby in Season 4, Episode 9: I Know What You Did Last Summer as Ruby grabs Sam’s hand and her demon killing knife while trying to stop him from risking his life.
9. Dean and Castiel in Season 8, Episode 7: A Little Slice of Kevin, a close-up of Dean and Cas gripping each other’s hands tight as they attempt to escape through the Purgatory portal together.
10. Sam and Rowena in Season 10, Episode 18: The Werther Project as Rowena grabs Sam’s hand over the Book of Damned as they agree to work together to find a cure for the Mark.
11. Claire and Kaia in Season 13, Episode 10: Wayward Sisters, holding hands as they prepare to enter the rift to the “Bad Place” together.
12. Dean and Crowley in Season 9, Episode 23: Do You Believe In Miracles? a close-up as Crowley brings the First Blade to Dean’s chest in order to revive him as a demon.
13. Dean and Castiel in Season 15, Episode 8: Our Father Who Aren’t In Heaven, a close-up of Castiel hovering his hand over Dean’s as he heals Dean’s hand wound for a spell.
14. Sam and Eileen Leahy in Season 15, Episode 6: Golden Time: a close-up of Sam and Eileen grabbing onto each other’s hands after Eileen’s resurrection and realizing it was a success.
Bonus: Castiel and Crowley in Season 12, Episode 3 The Foundry, a scene in which Castiel aggressively holds Crowley’s hand to stop him from antagonizing the witness.
