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When the dark tide recedes, you are left with a sun that is eating the galaxy and generations of children with stomachs for throats.
— Mary Sun, from “Metaplasia,” published in The Offing
For a long time, it was thought mature cells (those that constitute the tissues in living organisms) could not proliferate in order to repair any damage. However, a new study has uncovered the physiological process of paligenosis, the “other side” of apoptosis for injured cells.
SciShow “You Don’t Need a Uterus to Get A Uterine Disease”
Metaplasia is when already specialized cells change into a different type of cell, via inflammation triggers, and not just in still-developing children.
For example, mesothelioma cells around the testes or abdomen turning into endometriosis. Mesothelial cells are the ones that protect organs.
I believe this means that “sex reversal” is to some degree possible in humans.
Also, I believe this makes people intersex as those are intersex traits.
I wonder how much hormone pollution and hormone-acting substances (like plastic) can impact this.
Pancreas metaplasia: the malevolent unconsidered precursor that can be reverted with aimed molecules
Pancreas metaplasia: the malevolent unconsidered precursor that can be reverted with aimed molecules
Acinar ductal metaplasia (ADM) is a natural occurrence that follows bouts of inflammation such as pancreatitis to temporarily reduce the damage from over-secreting digestive enzymes in the pancreas. Characteristics of ADM include morphological changes as well as reduced expression of acinar genes and increased expression of ductal and progenitor markers (e.g. keratin-19 and SOX9, respectively).…
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PATHOLOGICAL STUDY OF INTESTINE IN THE INDIAN BULL FROG, Hoplobatrachus tigerinus DAUDIN PARASITIZED WITH Tremiorchis ranarum (DIGENEA: PLAGIORCHIIDAE) FROM YSR DISTRICT, ANDHRA PRADESH, INDIA | UTTAR PRADESH JOURNAL OF ZOOLOGY
Hoplobatrachus tigerinus Daudin, an Indian bull frog, was shown to be parasitized by Tremiorchis ranarum Mehra et Negi, a digenean. This parasite was discovered in the intestine of the host during a research of helminth parasites in amphibians from multiple locations in the YSR district of Andhra Pradesh. Light microscopy and scanning electron microscopy were used to investigate the morphological and diagnostic properties of Tremiorchis ranarum, as well as its pathological effects on the host intestinal tissues to determine the level of damage. The destruction of intestinal villi, inflammatory fibrosis, inflammation of villi at the site of parasite attachment, hyperplasia and metaplasia, vacuolation of submucosal cells, and degeneration of intestinal layers due to proliferative alterations are some of the histopathogical impacts. A thickening of the mucosa and injury to the mucosa are also harmful outcomes. Please see the link :- http://mbimph.com/index.php/UPJOZ/article/view/1760
Metaplasia of the stomach is a pathological process of replacing the cells of the gastric epithelium with intestinal type cells under various undesirable factors. The dynamics of this process can lead to dysplasia with further regeneration into cancer, and therefore intestinal metaplasia of the gastric mucosa (IMGM) is considered a precancerous mucosal change in adults.
Metaplasia
Cell type “evolves like a Pokemon” to better deal with increased stress upon the tissue