Discover Top Posts Tagged with #superoxide

The Scientific Research Notes of S. Sunkavally, Printed Part, Page. 457.

Years unclear, but definitely between 2006-2012.

#chili powder #tongue #vegetables #salads #freezing #winter #fish #unsaturated fatty acids #superoxide #tuberculosis #Eskimoes #beta carotene #respiratory epithelium #respiratory ailments #vitamin A #cold #lymphocytes #villi #theoretical biology

#dull #duster #barrack #superoxide #particularly #keeps #bustystars #lav #evanescence #bapt #massage #claimant #listening

The Scientific Research Notes of S. Sunkavally (years:2002-2011).

4400-4403.

#adrenal cortex #free radical scavenger #vitamin C #ferrous #SOD #copper #enzyme #scurvy #civilization #cortisol #europeans #chelated iron #citric acid #citric fruit #superoxide #manganese

Beach birds winging their way over the lustrous liquid silver of the Gosthani River.

The glare here is so intense and must be borne by these birds for such sustained stretches, essentially the entire day, that one marvels these birds do not develop an avian version of snow blindness!!.

We need sunlight to see but sunlight is also detrimental to sight!!!. The ultraviolet rays present in it can cause an opacity of the eye lens - cataract - a serious matter considering that this causes blindness in about 25 million people worldwide. And if there is one species that truly needs ultra-sharp vision for its livelihood it is the high-flying bird!!! Birds don’t peer!!!.

The UV glare from the mobile mirror-like surface of these water apparently cause photo-oxidation of the crystalline proteins in the eye lens, not to mention the generation of superoxide and other reactive oxygen species that do further damage.That the eye lens contains one of the highest concentrations of the antioxidant Ascorbic Acid does not now surprise us!!!

The eye lens is especially vulnerable not only because its proteins are held at super-saturation, making them very vulnerable to precipitation by any chemical or mechanical injury, but in addition do not undergo any molecular or cellular turnover. The lens proteins you are born with are all that you will have for life, and upon reflection it is little short of a molecular miracle that they stay clear and crystalline as long as they do - seven decades.

Cataracts due to relentless sun exposure and glare while out at sea in low-lying boats - that shortens the distance between the shiny surface and the eye - beset the 50,000 fisherman of Srikakulam district - about 130 kilometers from here - many of whom develop lens opacities in their forties precluding many of them then from making a living, a serious matter in a people who essentially live from hand-to-mouth..

How these birds - doubtless long-lived, and fishermen in their own right!! - manage to keep their eyes and vision intact over a lifetime - assuming they do, they well might not - is a puzzle that needs explication.

The puzzle is further accentuated by the fact that reflected light is mostly polarized light, and as the pharmaceutical industry has known for a long time, polarized light is far more potent in producing molecular damage than un-polarized light.

May 10, 2010, Gosthani River confluence, Bheemili, Visakhapatnam, Andhra Pradesh.

A shoal of tiny fish sheltering in the shade provided by the stern of a fishing boat anchored slightly upstream of the confluence of the Gosthani River.

Water is actually an opaque substance that absorbs both very long wavelengths such as Infra-Red - (700nm - 1 mm), and which makes up more than fifty percent of the energy of Sunlight - and very short wavelengths below 200nm.

It is transparent to the wavelengths between 200 nm and about 700 nm, that encompasses both visible light and the invisible Ultraviolet Light. And it is transparent to them because of a failure of quantum energy packet matching between the electronic, vibrational and rotational energy levels of the water molecule and the quantum packets of energy carried by these particular wavelengths. Not able to absorb these wavelengths into its electronic, vibrational or rotational energy levels, water, in a sense, “allows” these wavelengths to pass through - hence the transparency !!!. Water is clear, transparent, because of a failure!!!.

Ultraviolet light, particularly UV-B (290-320nm), is very damaging to cells, and water is especially transparent to it, only about 50% of UV-B being absorbed by the water even at 30 feet depth.

Fish living in deep lakes or deep rivers can go to deep depths to escape this fracturing photonic flood. Not so here given the shallowness of the stream. These fish therefore are staying out of the light for good reason, since UV-B can cause extensive DNA damage such as single strand breaks and Thymine dimer formation, not to mention free radicals and superoxide that are damaging to the cell in general. Indeed a case can be made that the nuclear envelope of the nucleus arose in Evolution to shield the chromosomal DNA from this fracturing flood of photons in the Proterozoic Era.

Being in the shelter of the stern might also prevent them from being swept downstream in the river current.

The Gosthani River. May 10, 2010. Bheemili. Andhra Pradesh.