The thing I find most fascinating about Spider Gwen in general and Matt Murderdock in particular is the way their narrative and themes so directly contrast and contradict and comment on 616 canon.
Like. I just read the Death of the Stacys, and these are such iconic moments in the history of Spider-Man, but at the end of the day Gwen Stacy's death is so much more about Peter's grief than it is about Gwen's life being cut short. Meanwhile in Spider Gwen we don't even get to meet Peter before he dies; his entire purpose is to haunt Gwen, to be her Uncle Ben and Gwen Stacy and Green Goblin combined, even before Harry turns into earth 65's Green Goblin. He is the one who drives her to be a hero, who drives so much of the plot, a stand in for her failure and yet also the reason she continues to do what's right. His death haunts her not exactly in the way Gwen's death haunts Peter, because they weren't romantically involved, but also not exactly like Uncle Ben haunts Peter, because they were peers, childhood friends.
The fact that Peter is so much of a character in Spider Gwen comics but only after his death is a direct commentary on the fact that Gwen Stacy is often relegated in 616!Spider-Man comics to "the dead girlfriend", maybe his biggest failure as a hero, but not much else. In the introduction to Death of the Stacys, Gerry Conway calls her "boring". She was Peter's girlfriend, but not much else - the TASM movies made her incredibly interesting, smart and funny and charming, but the original comics, back in the 60s and 70s, weren't particularly interested in making her much of anything at all.
65!Peter has, on the other hand, such strong characterization that even though we never once see him alive we can't help but feel Gwen's grief even without having spent much time with him. There's also the fact that while by the time 616!Gwen dies she has no family left, 65!Peter's Aunt May and Uncle Ben are very much still alive and actively mourning their nephew's death. It's difficult to impossible while reading Spider Gwen comics to not constantly compare these two stories and see how much more deftly handled 65!Peter is than 616!Gwen.
The fact that traditionally Daredevil and Spider-Man are friends, then, is part of what makes Matt Murderdock such a compelling villain. By all rights he should be Gwen's closest ally; and while he is drawn to her, it is from the perspective of someone trying to ruin everything she stands for - everything 65!Peter's death has taught her to try to be. He, himself, is 616!Matt's complete inversion - he's a killer, he's a member of the Hand instead of fighting against them, he's actively the Kingpin (and previously friend to Wilson Fisk) instead of fighting against organized crime, and while he was roommates with Foggy in college, they are not partners in a productive fashion, but rather in a way that shows corruption in 65!Foggy that 616!Foggy is constantly learning to fight against. Murderdock is a lapsed Catholic, a man whose morals are in complete opposition to 616!Matt - and yet, in a way, he feels as though there's something deeply wrong in who he is, and that is what drives him to try and corrupt Spider Woman. He says it himself - it is a selfish need to prove that he is not the only one who is corruptible. In a way, it actually proves that at his core, given other circumstances, he would have grown into someone very similar to 616!Matt.
This is what compels me so about Murderdock and the Spider Gwen narrative. Yeah, Murderdock is a sarcastic twink and I love him for that too, but on a thematic level it is not only its own story, but also a story about our main continuity. What 616 did wrong, and how it could have gone wrong. And that's just... So interesting to me.
