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izzy's playlists!
One Nice Bug Per Day
taylor price
2025 on Tumblr: Trends That Defined the Year
trying on a metaphor
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Lint Roller? I Barely Know Her

Discoholic 🪩
Game of Thrones Daily

@theartofmadeline
NASA

ellievsbear

oozey mess
hello vonnie

Origami Around

Kaledo Art
$LAYYYTER
"I'm Dorothy Gale from Kansas"
RMH
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@midnightminx90
I am both the yapper and the person who can go a whole day without saying a word.
but ykw at least i'm not on mount everest. at least i'm not paying tens of thousands of dollars to slowly suffocate in a 300-person line at the gates of hell. never in my life will i have to be steered in a hypoxic stupor through the maze of poop and corpses atop mount everest. on this earth a lot of horrible things can happen to you without your permission but there are a few that you have to opt into. you can just say no thanks! and be guaranteed never to have to be on mount everest. much to be grateful for actually
still not on mount everest this morning 😌 alhamdulillah
anyway hoping that the generative AI bubble pops so disastrously that the tech industry becomes allergic to anything involving it for the next 1,000 years
What even is cmq5 about
I need a sapphic knight romance book from Casey more than I need anything else in this world
Giggling
Bro just give me the modern lesbian x fantasy lady knight novel already
I forgot to post these oops
Boy time is overrr💥📣
Alright
Wait so this is what that was
Also, remember these ones
Ah yes, the surest sign of spring; everything reeking of manure
Man I really miss the old days of shows coming out with a new season like twice a year bc what do you meaaan i have to a other year for the next season of xo kitty whilst simultaneously worrying it won’t be renewed????
It’s Easter, so I’m joining the age old tradition of reading crime and mysteries and uuuuh Hastings??? Wtf
whenever I see archeological remains of a human who suffered from a terrible disease that couldn’t be treated in their lifetime but could be fixed now, this wave of sorrow and mourning washes over me. a woman in the 14th century who spent her 35 years of life bent at the waist because of congenital scoliosis. a man from the 18th century who died because of a non cancerous mass on his jaw that made eating progressively more difficult. remains of a woman from the Neolithic who died in childbirth having evidence of peri-mortem trepanation on her skull.
and yet she survived to 35. and yet the physicians in his time tried to strengthen his jaw. and yet someone 4,000 years ago tried to save someone they loved from dying of preeclampsia/increased cranial pressure. we tried. we tried and we tried and we tried. we failed and we learned but we tried. that’s what makes humans so beautiful.
My mom sometimes talks about a child in her neighborhood who was born with hydrocephaly and died of it. His parents strove to keep him alive for years, but he ultimately passed after a long decline. No treatment available. No hope at all, and the parents knew it from his birth.
Several decades later my sister had an MRI, as a long shot, to try to figure out why she was sick and deteriorating with a number of symptoms that were close to being written off as anxiety. She was sent straight to the hospital for adult onset hydrocephaly. Two days later she had brain surgery to put a shunt down her neck into her stomach and drain the fluid out. (No, you cannot usually get brain surgery that fast. Yes, it was that urgent.) Recovery was long and squiggly but it happened.
I think of that boy every once in a while. The one who died. I have no doubt that treatments developed for people like him, and tested on people like him, saved my sister's life.
He never knew he made the world better. His condition was severe, he never knew much of anything, I don't think. I think if I ever track down a God or something like one, that'll be somewhere on my List of Wishes. To make sure people like him know that they helped.
I think about this a lot.
I've been type 1 diabetic since I was about one and a half, and was incredibly sick. If my mother hadn't also been type 1 and recognized the signs I likely would have died.
I was born in 1982. Insulin was first given to a patient in 1922, and he survived. Before that, type 1 meant death, often very slow and agonizing. Before insulin, doctors advised a super strict "keto" diet to prolong life, and it could work for awhile - up to a year, I believe. But it was a miserable existence as the body was literally eating itself as the blood turned acidic until the patient eventually died.
60 years. Only 60 years before my birth did that procedure work for the first time. That's absolutely nothing given the span of human history and I think a lot about the people who died from it throughout time.
But yes, people tried. Healers and doctors of all sorts tried all manner of things to allow these (mostly!) kids to live. The fact that it was accomplished at all is nothing short of a miracle. The fact that I've been alive 42 years is fucking insane considering my body doesn't produce a hormone necessary for survival. If you think that doesn't blow me away on a regular basis you have another think coming. It's nothing short of a miracle.
Every medical advancement is. The amount of work that goes into it and the vast amount of luck necessary to get it right even when all the research and information is sound is just astonishing.
Thank you, humanity. Thank you ingenuity and determination to save lives and make them better. Thank you to every medical practitioner and medical researcher in existence now and through all of time. Thank you to all the people who died so I could live.
Diabetes is one of these illnesses that really throws medical history into perspective. It's so common, everyone knows someone who has it, people live pretty normal lives with it. And yet, a hundred years ago, it was an instant death sentence. And then we were able to treat people with insulin and yet - it was extremely disabling. The insulin was extracted from animal pancreas had severe side effects, even with how similar the hormones are, there is always an averse reaction to proteins from foreign species, especially during long-term treatment. Injections had to be given every few hours, at-home-tests were only available from the 70s onwards. Insulin pumps entered the market in the 80s. Genetically produced insulin - humanized insulin - was first available in the US in 1982, in many countries only around the year 2000.
In 1930, having diabetes type I would basically mean being hospital bound, being woken every few hours for regular injections.
In 1965, you'd be able to live at home and get by with a very strict diet and a few timed injections. You'd struggle with chronical side effects. Having children wasn't done - passing on your genes would be immoral, and it might not even be legal for you to marry.
In the year 2000, you'd have a device clipped to your belt that would measure your blood sugar and distribute insulin, you only need to change the needle a few times a day. You might even be allowed to join in P.E. class
In 2025, you stick on two patches that do the same thing. They're synchronized through your phone.
That wasn't fate. It's not natural development that made diabetes a common chronic illness. It was hundreds of people who cared. It was the people who created the keto diet. It was the people who came up with tests. The ones who went through different species, trying to figure out the closest analogon to human insulin. It was the people who fought in court to get genetically produced insulin approved for medical use. It was people who looked at a rare, incurable disease and said "but what if it wasn't?"
I have schizophrenia and a severe anxiety disorder. I have a good job and a wife and an apartment. This is because I also have escitalopram and risperidone. Risperidone came to market in 1993. There is another med I know works for me (haloperidol) that came to market in 1958, but which has a high risk of future side effects I would like to avoid.
Prior to 1958 I would likely have had to live in an institution, and I would have been miserable because my brain can do some very unpleasant things to me when not controlled with medication.
From 1958 into the 1970s, the dose of haloperidol they would have had me on would have been so high that severe and permanent disabling side effects would have been almost assured, and very quickly. My symptoms might be controlled, but working and having a family would likely be difficult or impossible.
I am grateful to live in an era where the medications that work for me are available and covered by insurance. And I look back and think of the hell that the people who had schizophrenia before me went through and I am thankful that science has learned and evolved.
The one that always fucks me up is lung surfactant for premature babies - The lungs do an incredibly difficult and complicated transition as they move from being soaked in amniotic fluid and "breathing" a liquid, to being out on dry land and needing to have their countless microscopic alveoli exposed to the air, to do the gas exchange needed. Before about the middle of the 6th month of pregnancy, if the baby is born, their lungs will still be in wet-mode and the alveoli will struggle to inflate. It used to be incredibly common that premature babies, even ones who were otherwise healthy, would drown in the air, slowly failing to get enough oxygen in their blood, until their brains were too damaged to live any longer.
And then in the late 80s or early 90s we managed to synthesise a surfactant which you could scoit into the lungs, once (I believe up the nose) and it would unstick all the alveoli and allow them to breathe normally. And suddenly, that wasn't a way that babies died.
Writing a story is so much harder than drawing it honestly I don’t know how authors do it
What do you mean you have to describe what your characters look like with WORDS. Can’t they just… figure that out? Why do I have to write an entire sentence if I want my characters to do anything?? How does that make any sense? I’d draw a thousand backgrounds over having to spend time writing a goddamn paragraph to set the scene smh
That’s funny because as an aspiring author I feel the opposite way. Words are like bricks, you just keep stacking them methodically, it’s easy but sometimes tedious.
What do you mean artists can just SHOW things? Like… you see it in your head and manage to somehow translate that image onto paper? You can just… get across what you want people to see without spending an hour trying to pick out the right words?? What is this witchcraft??
To me, it just seems more efficient than arranging words in such a way as to make people vividly hallucinate an approximation of your mindscape. AND YET.
People who write and make art:
KCD1 fans can confirm this happened, trust me
(still crazy to me that the writers in the first game had Hans and Henry in the bath tub 0 ft apart cuz they're gay, and forced us to wait 7 years before they got together smh. slowest most well written work of romance in any game!)
The High Court of Andhra Pradesh in India has ruled in a landmark decision that trans women are legally recognised as women.
HUGE GOOD NEWS
the world may seem bleak but PLEASE take time to feel the trans joy and to be happy for our sisters in India
"...The Lord does not look at the things people look at. People look at the outward appearance, but the Lord looks at the heart." - 12.1 Samuel 16:7 |10022026 - You want to see WIPs, exclusive content and artworks earlier? Consider supporting me on Patreon ✨
If I was Denethor the second, Steward of Gondor I would not have sent my son to a council meeting to try and get a cursed ring- I would have sent both my sons out to Seduce Aragorn by any means necessary.
If I wanted the crown of Gondor and to secure leadership for my family for all time I would have said boys. Get out there. Make it happen. Fluff your beautiful shiny hair up. Make papa proud
you cannot just leave this in the tags @greatmolassesflood
"Boromir, impress him with your manly charm and sexual charisma. Faramir, some guys are into pathetic wet sacks, I guess."