Me, watching the masterpiece that is del Toro’s Pinocchio:
Color Me Curious

oozey mess

@theartofmadeline
No title available
RMH
"I'm Dorothy Gale from Kansas"
ojovivo

Product Placement
let's talk about Bridgerton tea, my ask is open

if i look back, i am lost
untitled
Fai_Ryy
occasionally subtle
Claire Keane
No title available
EXPECTATIONS
d e v o n
Monterey Bay Aquarium
The Stonewall Inn
PUT YOUR BEARD IN MY MOUTH
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@missespipehead
Me, watching the masterpiece that is del Toro’s Pinocchio:
Bocchi the Rock! - Episode 03: Be Right There CloverWorks, 2022
IT’S THAT TIME OF YEAR AGAIN
thanksgiving is a time to squanto
Bringing this back because this post is a holiday classic
シーツを敷くとやってくる https://nekonavi.jp/catblog/archives/60859 https://twitter.com/kyuryuZ/status/1410795387536003075
can’t read this but I understand it completely.
That bitch saw the rise of Hirohito and did nothing
General Charles De Gaulle is well known throughout modern history as the leader of the Free French Forces. What is not as well known is that his youngest daughter Anne (January 1, 1928 - February 6, 1948) had Down syndrome.
Although public perception of the time was that children born with Down syndrome were a result of their parents alcoholism, venereal disease or overall degeneracy, the De Gaulles rejected this notion, choosing instead to raise Anne like their other two children. Their personal life became very private and Anne was raised at home, not in an institution (as was common practice at the time).
Charles and Anne on holiday in Brittany, 1933 It has been said often that Anne was Charles’ favorite child. Described as a man who ranged from cocky to stoic by nature, he was a different person around Anne, reportedly describing her as “My joy”. He is said to have read stories and sang songs to her and showed an affection that he rarely showed others, even those in his own household. Anne was raised to feel no less or different than anyone else.
After the war, Charles and his wife Yvonne founded the Fondation Anne de Gaulle, a home for disabled girls, many of which had intellectual impairments. In 1948, Anne succumbed to pneumonia, a month after her 20th birthday and died in her father’s arms. Upon her death, he is said to have remarked “Maintenant, elle est comme les autres.” (“Now, she is like the others.”). He carried a portrait of Anne with him at all times; he claimed that her portrait saved his life by stopping a bullet in an assassination attempt in 1962. When Charles died, he was buried beside his beloved Anne.
(Via Facebook.)
Huh, never knew that!
If sex is a service rape is just unpaid labor.
If sex is a service it can be provided to family members, morally.
If sex is a service it can be a small child’s career aspiration, and it should be supported as such.
If sex is a service then pornographic content can also be displayed to children,as they should be given examples of their work possibilities.
If sex is a service, and sex work is an existent opportunity to you, you can’t complain about being unemployed.
If sex is a service csa is just some form of child labour.
If sex is a service it is bigoted and against the costumer rights to denny service on the basis of anything, including sex, regardless of the workers orientation they should provide service to the costumer.
Things get really creepy when you mix things with inherent different natures like sex and labour, I know.
If sex work is work, then incest is no different than working in the yard or shed with mom and dad. It’s just practice for working in the real world.
If sex work is work then it should be held to the same safety standards as other jobs, including treating any and bodily fluids as biohazards that should never touch the workers’ skin (rubber protective gloves, etc). There would be unions, benefits, healthcare, the things expected from other jobs. Legal action against pimps when they harass, assault, and threaten their “employees.” Strikes, protections, wages that increase rather than decrease over time (why would an 18 year old be more “valuable” than a 30 year old?).
Are you starting to see it now. Sex work is ultimately the exploitation of women and will never be empowering
this posts helped to change my entire worldview. literally.
i think if more young women were exposed to these types of posts, being anti-prostitution would be a lot more normalized
Do you guys remember when Warner Bros. Discovery said Batman and the Looney Tunes characters were important brands? Because all I'm seeing is them throwing them away
Reminder that St. Joan of Arc was officially executed for heresy but unofficially it was because the Norman King didn't like that she was a French peasant girl and not because she wore men's clothes.
In fact, she rarely wore men's clothes. There are multiple accounts of her refusing to wear men's clothes when asked to do so for her protection.
Also because I saw it on Twitter, she was catholic. Not just a "catholicism respecter" whatever that means. My dude she's a catholic Saint.
Literally had the voices of angels speaking to her
“Fifty years ago, if you questioned authority, distrusted large corporations and governments, hated censorship, liked crass humor, thought schools brainwashed kids, and wanted to focus on domestic issues, you were absolutely a hippie leftist. Twenty years ago, you were a normal liberal. But today, holding those opinions will see leftists label you as a fascist.”
—
ShortFatOtaku
The fact that someone can, in clear conscience, call me a nazi for a belief I’ve held since the Iraq invasion pisses me off to no end.
Last month, drug company Genentech reported on the first clinical trials of the drug crenezumab, a drug targeting amyloid proteins that form
fucking livid
Last month, drug company Genentech reported on the first clinical trials of the drug crenezumab, a drug targeting amyloid proteins that form sticky plaques in the brains of Alzheimer’s disease patients. The drug had been particularly effective in animal models, and the trial results were eagerly awaited as one of the most promising treatments in years. It did not work. “Crenezumab did not slow or prevent cognitive decline” in people with a predisposition toward Alzheimer’s.
Last year, the Food and Drug Administration (FDA) narrowly approved the use of Aduhelm, a new drug from Biogen that the company has priced so highly that it’s expected to drive up the price of Medicare for everyone in America, even those who never need this drug. Aduhelm was the first drug to be approved that fights the accumulation of those “amyloid plaques” in the brain. What makes the approval of the $56,000-a-dose drug so controversial is that while it does decrease plaques, it doesn’t actually slow Alzheimer’s. In fact, clinical trials were suspended in 2019 after the treatment showed “no clinical benefits.” (Which did not keep Biogen from seeking the drug’s approval or pricing it astronomically.)
Over the last two decades, Alzheimer’s drugs have been notable mostly for having a 99% failure rate in human trials. It’s not unusual for drugs that are effective in vitro and in animal models to turn out to be less than successful when used in humans, but Alzheimer’s has a record that makes the batting average in other areas look like Hall of Fame material.
And now we have a good idea of why. Because it looks like the original paper that established the amyloid plaque model as the foundation of Alzheimer’s research over the last 16 years might not just be wrong, but a deliberate fraud.
thanks for the text extraction, i was on my phone <3
Jesus christ
It’s not just that drug trials are wrong. They created a false diagnostic criteria for Alzheimer’s. EVERY study in the last 15 years is wrong. Every diagnosis from that time is questionable. These dudes should be hanged.
christ.
An abridged TLDR of the meat of it:
”The results of the [2006] study seemed to demonstrate the amyloids-to-Alzheimer’s pipeline with a clarity that even the most casual reader could understand, and it became one of—if not the most—influential papers in all of Alzheimer’s research. Not only has it been cited hundreds of times in other work, roughly 100 out of the 130 Alzheimer’s drugs now working their way through trials are directly designed to attack the kind of amyloids featured in this paper. Both Ashe and Lesné became neuroscience rock stars, the leaders of a wave based on their 2006 paper.
What intrigued Schrag when he came back to this seminal work were the images. Images in the paper that were supposed to show the relationship between memory issues and the presence of Aβ*56 appeared to have been altered. Some of them appeared to have been pieced together from multiple images.
Now Science has concluded its own six-month review, during which it consulted with image experts. What they found seems to confirm Schrag’s suspicions.They concurred with his overall conclusions, which cast doubt on hundreds of images, including more than 70 in Lesné’s papers. Some look like “shockingly blatant” examples of image tampering, says Donna Wilcock, an Alzheimer’s expert at the University of Kentucky.
Trust the Science.
My mom was a fourth grade teacher, which meant that she did multi-subject education. And she used to do what she called the NFL Project. The NFL Project was when students were randomly assigned NFL teams.
They had to write a letter to the NFL team they were assigned to, they had to do a research project to find out where the teams practiced, they had to write a letter to the mayor of the city the teams practiced in, they had to keep track of their team's statistics, they had to do research about the state history of the team they'd been assigned to, and they had to do a presentation.
It was a big project. She provided all the materials, she made sure there were copies of the newspaper sports section in her classroom so the kids could stay on top of stats. The students got this project in their first week at school and it wrapped up right around winter break, so it wasn't like it was an all-day "today we are doing statistics" thing or "today we do research, today we write a letter, today we make a presentation" one-week project, it was five to ten minutes a day in various subjects that got organized into a presentation at the end of the semester. The kids could work together, they could work independently, they could ask my mom or the librarian or their parents or their older siblings for help. They just had to end the semester with a report on the team's history, the stats for the season organized into a chart, copies of the letters they'd sent (and copies of any of the responses they'd gotten), a two-page social studies report on the state where the team played, and a presentation to the class about their favorite thing they had learned while doing the NFL project.
The kids fucking loved it. And for years I spent my winter break going to the classroom and organizing the bulletin board with a huge map of the US and materials from each student's report, showing the work that the students had done that semester. It was a way of getting kids engaged with classwork, because who cares about statistics at 10, probably nobody, but if you get a set of pencils from the Jets NOW you want to learn about the team. The Jaguars sent one kid a jersey one year. The city in Minnesota where the Vikings practice sent postcards for every student. Part of this was happening when Schwarzenegger was governor in California so one kid got the Terminator's autograph for part of his project.
I think maybe the thing that I admire the most about it in retrospect was the way that it taught actual project management to young students. I don't actually know of that many schools that have projects more than a month long for 10-year-olds, and I think it's a great concept. I didn't get something like that until I was a senior in college, and it would have been a great skill to learn younger.
Anyway, in 2006 my mom had to stop doing the NFL project because the district wanted to focus on raising their test scores. She was specifically told that if she kept doing the NFL project she would not be rehired at her school.
She even wrote up what standards each part of the project worked toward - the kids had to make graphs because "organizing information into a bar graph" was a specific standard for students that age. "Writing multiple paragraphs on the same subject" was a standard, which is why the letters to the cities and states were multi-paragraph. The project WAS standards based.
But the administrators wanted to make sure that the students had more practice with reading the kinds of questions that would be on the tests because most of the student body spoke Spanish at home.
My mom taught at that school for another ten years; the school's test scores never showed any marked improvement with test-based lesson plans.
My mom's project wasn't the only thing like that that got cancelled. There was another teacher who had a craft-based thing that was similar, and a 7th-grade teacher who did a kind of history/social studies Magic Schoolbus LARP thing who was told not to do that anymore. Eventually my mom was told to stop having her students write journals for ten minutes a day because it wasn't being taught from the textbook and wasn't being taught to the test.
People joke (haha, it's funny, it's a joke, right?) about American education being used to prepare students to be good employees instead of to be critical thinkers or independent people, but legitimately it seems like NCLB directly incentivized "students sit quietly in a box filling out bubble sheets and have no unsupervised or creative work time."
The federal hold on education is nothing more than a tool to dumb down each generation and demean the teachers trying to make a difference.
oh yeah have i ever told yall of the academic war i have been an unwilling soilder in for the past two years
okay SO. i have two professors that both teach this one subject, but different classes. they have different last names, so i didnt know this at first and espically since they are academic RIVELS at my school, but they are MARRIED. but for the past 8 years they have been in an academic WAR of geospatical sciences data. more accurately, the raster vs vector data debate. i am personally on the side of "both have their pros and cons and can be utalizied to the utmost efficency" but both professors are like, DEADLOCKED in insistanting one is better then the other
so, professor A is my mentor. i like him a lot, and he was the main person that taught me the most abotu Eris and ArcGIS. professor B is a professor i had one for class, and shes nice and knows a lot of little tricks about Eris programming but mostly relies on arcMAP because shes the raster data professor.
and THESE MOTHERFUCKERS. have written no less then 30 papers that is basically like a "re: re: re: re: re: re: vector data is better then raster fuck you" but like, Professionally. and they leave stupid notes in the footnotes that read "Reguardless of Professor A's opinions reguarding the efficency of Vector data, Raster data has a more efficant polygon computing rate and is the most commonly used program on interplantaring mapping" and its HILARIOUS
ive read all of their papers, and its basically like reading an email chain between a married couple arguing over the colors of the kitchen backsplash for their new home. its HILARIOUS. but obviously, because of their differnet last names and because they act like they HATE each other, NOT VERY MANY PEOPLE REALIZES THEYRE MARRIED
until like LAST WEEK
professor B publishes a paper that casually drops the word "husband"
and obviously all the students are like "oh i didnt know u were married!" because we read that shit like how white suburban mothers read People Magazine
and shes like "yeah, its Professor A"
and we all FLIPPED. THE FUCK. OUT
we thought the framed picture of the two of them on professor A's desk was ironic because hes that type of guy
like, you gotta undestand. these two have gotten into YELLING matches in hallways. these two refuse to go onto trips with each other. but apparently they have a system where they quite LITERALLY leave all of their work at work and drive home in seperate cars and literally NEVER mention work at home. it is SO funny
Legal amphetamines are included, as well, however they usually ask about prescription meds before anyway.
Weed is also important to tell them about! It won’t kill you like amphetamines might, but it can make the anesthetic work less.
This isn’t trashy, this is responsible. Also applies to adderall, which many people (including myself) use for adhd/add.