genuinely me
Stranger Things
todays bird
One Nice Bug Per Day

祝日 / Permanent Vacation
dirt enthusiast
No title available
"I'm Dorothy Gale from Kansas"

No title available

Andulka
Cosimo Galluzzi
Alisa U Zemlji Chuda

roma★

tannertan36
cherry valley forever
TVSTRANGERTHINGS

Origami Around

izzy's playlists!

★
NASA
YOU ARE THE REASON
seen from Colombia

seen from Türkiye

seen from Malaysia
seen from United States

seen from Bangladesh
seen from Indonesia
seen from United States

seen from United States
seen from United States
seen from Netherlands

seen from United Kingdom

seen from United States
seen from United States
seen from United States

seen from Germany
seen from Morocco

seen from Malaysia

seen from Malaysia

seen from United States
seen from Romania
@blackeyedprince
genuinely me
is jake gyllenhaal gay??
why would you ask us, a narnia blog, this
happy pride month to this post specifically
At Toba aquarium in Japan, after closing time, some clever little otter pups help their grandpa tidy up their toys. As a reward, he gives them ice cubes
(crawls on all fours with blood drenched on me) I have to do arts and crafts
similar vibe to this absolutely unhinged car
I am pro-strike I am pro-union I am pro-workers-getting-their-due I want to be inconvenienced A THOUSAND TIMES if it means people earn enough money
Broadway theatres ✅ empty
Media content ✅ running low
Packages ✅ late
Awards shows ✅ canceled
Red carpets ✅ nonexistent
Travel plans ✅ delayed
Human rights ✅ more important
the cognitive dissonance from people who want the products of modern medicine but get weird about animal research. like im sorry but this is necessary for the survival of the society we currently live in. and the scientists who work on these things are not evil cackling psychopaths. anyone you talk to in animal research has incredibly complex feelings about their work and incredibly complex relationships to the animals in their care. there are regulations and oversight and penalties in place to make the work as humane as possible and scientists are overwhelmingly the ones enforcing and advocating for better care.
@velvetdemon I'm doing a full reply because I want to give this question the time and space it deserves, and I really do appreciate your curiosity about this.
The short answer: It is deeply unethical. There are nowhere near enough willing patients in the world to be able to do this, and it would be criminal to put them through this.
The long answer: The one side of the equation you're focusing on is: how much of a drug is too much, to the point where it will cause negative side effects or even death? And this is crucial to know. But it's not just a matter of finding out the lethal dosage of a heart cholesterol medication, you need to know that it can actually lower the cholesterol of any living thing. There is no way to know this without giving it first to...a living thing.
But beyond this, I need to emphasize: The goal of a drug trial is to effectively cure people who are already suffering from disease, who are living on limited time.
Drug trials don't just happen on any member of the public, they need to happen specifically on people affected by the disease you're trying to treat. There is at any time a very limited and very marginalized population of the world affected by early onset, familial Parkinson's disease. Because you cannot ethically induce disease in a human being, you are working with, speaking with, and helping patients and their families who are hopeful and desperate for a cure.
If you were to jump straight to human trials from petri dishes, not knowing absolutely anything about how the drug functions in a living, breathing animal body, it would look like this:
We didn't know that minute quantities of the drug interact lethally with x, y, z medication that people are commonly also taking. X number of patients have died as a result.
We didn't know that the drug is fatal to people with [common variant] in their genetics. X more patients have died.
We didn't know the drug exacerbates x, y, z chronic illnesses. X number of people have acquired permanent, lifelong disabilities.
We didn't know the best way to deliver the drug, so we tried multiple ways: the people who received it intravenously are now suffering from a painful, costly, and debilitating condition that did not happen with the ingested form.
I could go on, and on, and on.
The vast majority of these problems can be nearly or almost entirely averted by testing other animals first.
These are all people who possibly could have waited for the normal progression from animal testing to human testing and thus received better outcomes. Some people will pass away in the time it takes to get to that point, and that's heartbreaking, and we all wish science could be faster.
But the cost of expediting science could mean a life of profoundly greater suffering or an even shorter life than the one where no intervention happens at all. And at that point, you have completely exhausted your trust, your goodwill, and your patients' hope, after you've failed to do anything or even worsened the lives of people who are already deeply suffering.
hi, i’m an animal research professional. making sure laboratory animals stay alive, healthy, and enriched has been my full-time job for several years now.
animal research is not the mad scientist wild west that PETA wants you to think it is. there are extremely strict federal laws in place to protect the well being of these animals. animal welfare organizations like AAALAC ensure that lab animals are treated with dignity & respect and are given enough specialized care & enrichment to be happy and content in captivity, just like AZA accreditation with zoos.
not a single animal from a zebrafish to a mouse to a dog to a macaque goes unaccounted for. if an animal gets moved to a new cage, paired for breeding, has a procedure performed on it, gives birth, gets sick or injured, dies, etc. it is legally required that this information is recorded and kept on file for the US federal government to access. failing to record & retain this information is very much punishable by US federal law.
let me tell you - if you abuse or kill an animal, even a mouse - you are almost certainly getting both fired & blacklisted from the industry. if you abuse or kill a more ‘advanced’ animal, such as a dog or monkey, you will likely face criminal charges. killing a monkey is as serious and disastrous as a nuclear meltdown. you are expected to reasonably explain every illness, injury, or death of an animal under your care. you must record all of this information. animals that are clearly suffering with low QOL are required to be euthanized according to AVMA guidelines.
research animals are highly expensive. yes, even the "lesser" animals like mice. the cheapest mice will run you a few hundred $ per individual, with some of the most expensive mice i've cared for being $25,000 per individual. in research we have the "three Rs" - reduction (reduce amount of necessary animals to a minimum), refinement (refine processes to ensure research is accurate and animals feel no pain or distress), and replacement (replace animals with non-living research models as they become available). i can assure you no proper research team is wasting animals (*do not* say "b-b-but elon musk--" his research team is actively being investigated for animal abuse by the government).
research methods that do not require live animals are currently being looked into & efforts spearheaded by - you guessed it - the animal research industry itself (notice how the animal rights people are strangely silent & unhelpful when it comes to this?) but current technology is rudimentary and does not compare to live animal models.
some research animal fun facts (US edition):
all species of animals are only allowed to have one single major surgery performed on them in their entire lifetime.
institutions with nonhuman primates must have a behavior program in place (run by knowledgeable primate specialists) to ensure that they are happy and receiving enough daily enrichment and social interaction.
institutions with dogs are required to have physical exercise programs in place. this means every individual dog gets a substantial amount of leashed AND free-roaming exercise daily, including playgroups with other dogs.
a majority of nonhuman primates get to retire to sanctuaries like peaceable primate sanctuary, and almost all dogs get retired and adopted out by organizations like homes for animal heroes. some institutions will also adopt out unneeded young rabbits, guinea pigs, rats, etc.
some strains of mice glow neon green (or orange or blue) under UV light. this is not harmful to them and is commonly seen in cancer research.
so yes, you can rest knowing that laboratory animals are treated with the utmost respect by their caretakers. and you can stop this awful, ignorant talk of human experimentation that will only end in the abuse of nonwhite people, LGBT people, disabled people, indigenous people, and so many others. please just take a look at this wikipedia page if you think “ethical” human experimentation can exist.
Last month commissions
hualian ∞
I think the Heavenly Emperor Jun Wu must hate him. Why else would he banish him twice?
tbh the best way that i explain to other people what it feels like to live with an anxiety disorder is the one time when i had to get a fingerprint and background check done for a job and i, someone who has never received so much as a speeding ticket my whole life, spent thirty minutes panicking that i would fail because i might secretly be a criminal and have no idea
This is the most accurate post on anxiety ever.
Gosh he's so cool
new years eve!!! wooo!!! go crazy go wild! 🥳🥳🥳
the counterpoint to the millennial experience of thinking adult life would involve a lot more quicksand is that it turns out evil doomsday cults really are behind a lot of stuff irl. kind of a neat consolation prize
I genuinely love being at home. Nothing better than being in your own space.
American Girl stories were the best tbh
Dude, read the books, she and her mom freed themselves in Book 1. We don’t disrespect American Girl in this house
Don’t you dare disrespect Addy, or any of my girls for that matter. American Girl used to be legit. Good stories, good dolls, good movies.
Felicity’s story was set in the beginnings of the American Revolution, and addressed the conflict that she faced when her loved ones were split between patriots and loyalists. It also covered the effects of animal abuse, and forgiving those who are unforgivable.
Samantha’s stories centered around the growth of industrial America, women’s suffrage, child abuse, and corruption in places of power. Also, it emphasises how dramatically adoption into a caring family can turn a life around.
Kit’s story is one of my favorites. Her family is hit hard by the Great Depression, and they begin taking in boarders and raise chickens to help make ends meet. Her books include themes of poverty, police brutality, homelessness, prejudice, and the importance of unity in difficult times.
Molly’s father, a doctor, is drafted during the Second World War. Throughout her story, friends of hers suffer the loss of their husbands, sons, and brothers overseas. Her mother leaves the traditional housewife position and works full-time to help with the war effort. They also take in an English refugee child, who learns to open up after a life of traumatic experience.
American Girl stories have always featured the very harsh realities of America through the years. But they’re always presented honestly, yet in ways that kids can understand. They just go to show that you don’t have to live in a perfect time to be a real American girl.
Dont you fucking dare disrespect the American Girls in my house. ESPECIALLY Addy!! That was my first REAL contact with the horrors of slavery, as I read about her father being whipped and sold and her mother escaping with her to freedom, but also how freedom was still a struggle.
A slave doll. Please. Read the books.
Don’t forget Kirsten, the Swedish immigrant who had to deal with balancing her own culture and learning the english language and customs of her classmates, or Kaya (full name Kaya'aton'my, or She Who Arranges Rocks) , the brave but careless girl from the Nez Perce tribe, or Josefina, the Mexican girl learning to be a healer.
And then there are the later dolls, that kids younger than me would have grown up with (I was just outgrowing American Girl as these came out), like Rebecca, the Jewish girl who dreams of becoming an actress in the budding film industry, or Julie, who fights against her school’s gender policy surrounding sports in the 70s, or Nanea, the Hawaiian girl whose father worked at Pearl Harbor.
These books, these characters, are fantastic pictures into life for girls in America throughout the years, they pull no punches with the horrors that these girls had to face in their different time periods, and in many cases I learned more history from these series than social studies at school. And that’s without even mentioning the “girl of the year” series where characters are created in the modern world to help girls deal with issues like friend problems, moving, or bullying. We do NOT disrespect American Girl in this house.
American Girl is probably going to be the only exposure young girls are going to get to history from a female perspective. This is actually kind of important considering that in history classes we dont really get that exposure. We dont hear about what women felt and endured during these time periods cause schools are too busy teaching us about what happened from the male perspective, which is not unimportant, but we need both. Girls need both.
These books were such a crucial part of my childhood and shaped my love of history, which still ensures today. These books can be a young girl’s first lessons in diversity and cultural awareness (hopefully burying that insensitive “we’re all Americans” tripe) and looking at history from more perspectives than just that taught in school. They also are an example of how women have ALWAYS been part of history, which some people would rather us not believe.
I think Kit and Kaya were the newest American Girls when I started “aging out” of the books, but hearing about some of these kinda makes me want to revisit them!
I wasn’t gonna say anything, but you know what?
Nah.
OP (of the tweet thread) was either a actively trying to start shit or is just a huge fucking moron. Probably both.
I’d like to point out that the company that makes American Girl dolls actually doesn’t skimp when doing their research and they don’t make the dolls with the intent to be offensive in any way:
And they departed from the norm in Kaya’s doll to fit her culture! The other dolls all show their teeth, and Kaya does not because that is considered rude in the Nez Perce culture!
It is absolutely true that these books covered the stuff in history that was absent from our history books. I still distinctly remember reading about Addy being forced to eat bugs she missed on tobacco plants, and that started me out from a different perspective and made it easier for me to know to reject the sanitized version of the slave trade we’re taught in school. And these books are targeted at ages 8+, which is a pretty critical time for developing your own thinking and morals.
Reblogging for general awesome
when i was in 3rd grade i was reading the Meet Addy book at school & a couple boys made fun of me for reading a “doll book” - my teacher overheard & started reading Meet Addy to the class after every recess. everyone became extremely invested & by the end of the year we had read the entire collection of Addy books & did a presentation on the civil war at the end of the year that we all presented to the class one by one.
i think back on this & realize that as third graders we were talking about how awful slavery was & because we were simply innocent kids without any societal or institutional influence yet, all of us could kept saying “why would you treat a HUMAN like that ?!” this one girl for her birthday invited all of us for her party & she got the Addy doll - every single one of us (boys included) held her & was in awe of this doll - it was such a touching experience.
i went back home about a year ago & ran into my third grade teacher in the grocery store. she said that year opened up a whole new teaching structure for her. she now reads american girl stories to her students starting day one of class every day to calm them down after recess & she’ll get through maybe four or five sets of books a year. she has the dolls in the room with packets on information from the doll’s time period that her students can “check out” to take home for weekends to care for them.
we oftentimes overlook how powerful toys can be in influencing young children & american girl honestly knew that kids could read intense moments in history & synthesize the issues to learn how to be a better person. my grandma bought me my first doll, molly, when i was only six & the dolls became a huge part of my childhood. when i turned 21 a couple years ago - we were living in minneapolis - she took me to have lunch for my birthday at the american doll place in the mall of america & bought me the Addy doll for my birthday. it was such a powerful moment i hasn’t expected.
i’ve since gotten rid of majority of my childhood toys, but i still have every single one of my dolls & all the books that i plan on gifting to my future children.
I grew up with the Julie doll! One of my favorite parts of her books were her best friends. In the earlier books, her best friend was Chinese-American, and iirc in a later book she was friends with a deaf girl that communicated exclusively through ASL (with pictures included in the margins!). AG was SUCH a great place to learn about cultural identity.