Some people's upset around episode 2 probably seems a bit overdone. And in the general sense, of course it is, this is a show about vampires. But, in the sense of adapting the story, not so much. And I debated myself on waiting for more of the season to play out but, well.
There's a huge thread that weaves pretty much half this book together and that's the relationship between Lestat and Gabrielle. From the first page in 1700s France, until Marius finds Lestat in Egypt, the same story is told twice. The details are different, but the beats are the same. They are mirrors. I made a visual aid.
Gabrielle has admitted to contributing to Lestat's imprisonment in his home due to her selfishness. She could not let him go because of her need of him. He wasn't free until she atoned with the sacrifice of letting him go, and with him the last vestiges of her inheritance and former life.
Lestat's horrors with Magnus serve as amplified metaphors for Gabrielle's with the Marquis. A supernatural speed run of Gothic conventions. Gabrielle's turning then becomes an inverse of Lestat's birth. He is no longer alone in his suffering. But that doesn't complete the cycle. Despite the maker/fledgling "neutralization" of the parent/child dynamic, Lestat still needs a parental figure (read: someone who will teach him) but cannot and will not ask it of Gabrielle now.
He tries to step into the role of lover instead to maintain their companionship, but this ongoing need for a parent persists, expressed through his relentless search for Marius as they travel.
As the visual aid alludes, the reason for the breakdown between them and their separation is the fundamental difference between Gabrielle's fantasy and Lestat's nightmare.
Lestat is traumatized by his fight with the wolves and compares it to the "terrible" dreams he's had where he goes room to room killing the father and brothers. Gabrielle consoles him, saying that violent urge does not have to be the only way to be free.
Gabrielle then offers her own fantasy of freedom. Hers, however, is not a nightmare of giving in to the madness of murder, but of bodily liberation and disregard for her roles as wife and mother.
Vampirism has fulfilled the fantasy for Gabrielle. She is able to fully embrace her rebirth and power as a vampire, shedding her role as wife and mother (mostly).
Vampirism has robbed Lestat of his fantasies. Having his nightmare realized does not finally sever him from his humanity, but causes him to cling tighter, running to the very father that had imprisoned them both. The only other being left that knew him in his former life.
Gabrielle asks him if he can let go of his mortal life and all he was robbed of and embrace living as these new beings, away from their roles among humans. He cannot. Just as much as he can no longer ask her to stay in a facsimile of her mortal life because of his selfish need of her. She isn't truly free until he can let her go.
His following burial and exhumation then act as another rebirth, with Marius balming the parental wound.
So if you make Gabrielle a villain who kills the family, sexually assaults her son, and can't let go of her hold on him, I don't see how you capture all of that.