Broncho

They/him

[macgyvermedical]

When Drugs Became Available

Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:

Acetaminophen: 1950

Albuterol: 1969 (UK) 1982 (US)

Allopurinol: 1966

Alprazolam: 1981

Amitriptyline: 1961

Amlodipine: 1990

Amoxicilin: 1972

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Apixiban: 2012

Aripiprazole: 2002

Aspirin (first NSAID): 1899

Azidothymidine (first antiviral): 1987

Barbital (first barbiturate): 1903

Bupropion: 1985

Buspirone: 1986

Calcium Carbonate (TUMS): 1930

Captopril (first ACE inhibitor): 1981

Chlordiazepoxide (first benzodiazepine): 1960

Chlorothiazide (first thiazide diuretic): 1957

Chlorpromazine (first antipsychotic): 1952

Cyclobenzeprine: 1977

Diphenhydramine: 1946

Furosemide: 1959

Fluoxetine (first SSRI): 1988

Gabapentin: 1993

Glipizide: 1984

Hydrochlorothiazide: 1959

Ibuprofen: 1969 (UK) 1974 (US)

Insulin: 1923 (though many types of insulins would become available over the next century)

Imipramine (first tricyclic antidepressant): 1959

Iproniazid (first antidepressant (MAOI)): 1952

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Lisinopril: 1987

Lithium: 1949

Losartan (first ARB): 1995

Lovastatin (first statin): 1987

Naproxen: 1976 (Rx) 1990 (OTC)

Nitrogen Mustard (first chemotherapy agent): early 1940's

Methotrexate: 1947

Methylphenidate: 1954

Metformin: 1957 (France) 1995 (US)

Metoprolol: 1978

Montelukast: 1998

Morphine: early 1800's

Omeprazole: 1989

Penicillin: 1945

Phenbezamine (first antihistamine): 1942

Prednisone: 1955

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Sertraline: 1990

Spironolactone: 1959

Sulfanilamide (first modern antibiotic): 1935

Tolbutamide (first oral anti-diabetic drug): 1956

Tramadol: 1977 (Germany) 1995 (US)

Trazodone: 1981

Valacyclovir: 1995

Verapamil (first calcium channel blocker): 1964

Warfarin: 1954

Zopiclone (first "Z-drug"): 1986

[macgyvermedical]

Someone asked for this list in date order, so here it is!

Morphine: early 1800's

Aspirin (first NSAID): 1899

Barbital (first barbiturate): 1903

Insulin: 1923 (though many types of insulins would become available over the next century)

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Calcium Carbonate (TUMS): 1930

Sulfanilamide (first modern antibiotic): 1935

Nitrogen Mustard (first chemotherapy agent): early 1940's

Phenbezamine (first antihistamine): 1942

Penicillin: 1945

Diphenhydramine: 1946

Methotrexate: 1947

Lithium: 1949

Acetaminophen: 1950

Chlorpromazine (first antipsychotic): 1952

Iproniazid (first antidepressant (MAOI)): 1952

Methylphenidate: 1954

Warfarin: 1954

Prednisone: 1955

Tolbutamide (first oral anti-diabetic drug): 1956

Chlorothiazide (first thiazide diuretic): 1957

Metformin: 1957 (France) 1995 (US)

Furosemide: 1959

Hydrochlorothiazide: 1959

Spironolactone: 1959

Imipramine (first tricyclic antidepressant): 1959

Chlordiazepoxide (first benzodiazepine): 1960

Amitriptyline: 1961

Verapamil (first calcium channel blocker): 1964

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Allopurinol: 1966

Albuterol: 1969 (UK) 1982 (US)

Ibuprofen: 1969 (UK) 1974 (US)

Amoxicilin: 1972

Naproxen: 1976 (Rx) 1990 (OTC)

Cyclobenzeprine: 1977

Tramadol: 1977 (Germany) 1995 (US)

Metoprolol: 1978

Captopril (first ACE inhibitor): 1981

Trazodone: 1981

Alprazolam: 1981

Glipizide: 1984

Bupropion: 1985

Buspirone: 1986

Zopiclone (first "Z-drug"): 1986

Lovastatin (first statin): 1987

Azidothymidine (first antiviral): 1987

Lisinopril: 1987

Fluoxetine (first SSRI): 1988

Omeprazole: 1989

Amlodipine: 1990

Sertraline: 1990

Gabapentin: 1993

Losartan (first ARB): 1995

Valacyclovir: 1995

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Montelukast: 1998

Aripiprazole: 2002

Apixiban: 2012

[eisenkrahe]

I already keep track of a lot of this stuff but hey, it's useful.

[the-haiku-bot]

I already keep

track of a lot of this stuff

but hey, it’s useful.

Beep boop! I look for accidental haiku posts. Sometimes I mess up.

[bronch0]

I had my sister play deltarune for the first time and after fighting jevil for about an hour, she began theorizing about the knight almost immediately after checking Seam’s shop for items

[ryoyamadaily]

working for half a day at a metal fence factory has done immeasurable damage to both my body and my mind

[goldensunset]

[orgasmic-garlic]

reporting all ads as malicious because all ads are malicious

[the-haiku-bot]

reporting all ads

as malicious because all

ads are malicious

Beep boop! I look for accidental haiku posts. Sometimes I mess up.

[yujateaandpi]

Was driving with my grandmother and in broken English she says “no eyes… no nose… no face. Don’t trust.” To which I looked around wildly in search of this omen of ill portend.

Cybertruck. It was a cybertruck.

[eptck]

you have to be kinder to people with memory issues.

you have to be kinder to people who are slow processors.

you have to be kinder to people who don't understand your jokes.

you have to be kinder to people who forget important dates.

you have to be kinder to people with cognitive decline.

you have to be kinder to people who were always this way, too.

you have to be kind. you have to be kind.

[ryoyamadaily]

Girls look at this beauty i just found

[theoneofwhomisblue]

[blossposs]

[crispylilworm]

[theoneofwhomisblue]

[theoneofwhomisblue]

[lizardinashoe]

wait is this a symptom or just a silly little thing I do

[aflo]

A standard porno with the bad acting and music and whatnot but partway through the action the camera pans to a millipede and hunting spider locked in a duel for survival, the sounds of sex fade out and the scene in the background blurs, epic battle music starts to play

[uncertainlys]

MY FINGERS BARELY EVEN TOUCHED YOUR STUPID FUCKING AD STOP REDIRECTING ME TO THE APP STORE

[shutyourmoustache]

When my mother forgets a word, she is the queen of coming up with new words. Words that would take a third National Treasure movie to fully decipher. I was talking to her yesterday, and she said this: “You know the time for los jibbities is coming up. You must be so excited!” Oh, is it time for los jibbities already? I must have missed it on my calendar. Are we celebrating something? “Of course! We should all be celebrating, shouldn’t we?” OK, so los jibbities is a happy thing. It’s not like something is giving you the heebie-jeebies, which would have been my one and only guess. “Los heebie-jeebies? Now you’re making things up...and this is my show.” You’re right. The time for los jibbities is coming up. Is this a season? “Yes, the season for love. The season for pride.” OK, los jibbities. “Yeah, sound it out.” Los…jibbities. LGBTs! “Sí, mira cuz you’re gay!” “You couldn’t just say pride season? You couldn’t just… *laughs*

[party-gilmore]

HAPPY LOS JIBBITIES EVERYBODY!!!

[greatmountainfloofsquatch]

The time for Los Jibbities has arrived!

[cipheramnesia]

I need a polite way to email multiple people in a business environment that says, "Are you having an AI chat write your email replies? Because these are incoherent sentences and if it's a chatbot, I need you to stop."

[cipheramnesia]

I'm not trying to accuse anyone of communicating like an angry toddler with zero sense of object permanence, but I have received an awful lot of communications which ask for help with "it" while not specifying what "it" is, or asking me to send something while telling me they have it in the same sentence.

[cipheramnesia]

some mixed signals

[theprofessional-amateur]

I have a growing desire to return emails like teacher feedback on an assignment

"Thesis unclear and supporting arguments contradict leaving reader confused."

and in one particularly memorable and annoying case "Your email lacks even one complete sentence or verb. Your audience is forced to wildly speculate what you are asking or proposing."

[aru]

Tumblr Code.

[geekishchic]

If I ever see any of you in public, the code is “I like your shoelaces”

that way we know we’re from tumblr without revealing anything

I’m just going to say this to strangers until i find a tumblr person

must keep reblogering!! Im going to be so suspicious if any one tells me this now!

Remember the answer is: I stole them from the president.

always reblog tumblr identification

[princessnymphae]

my friend has a tumblr account but DOESNT know this… life is so empty

[bye-bye-sanity]

I FOUND THE ORIGINAL

[renderofbears]

@hellsite-hall-of-fame

[sailermoon]

this is how new yorkers @ mamdani

[sailermoon]

[beemovieerotica]

he literally ran on this campaign promise and won

[sideblogspam]

trying to apply for jobs and all these say the minimum qualification is “effective communication skills”. I am NOT getting in