DEAR READER
taylor price
Cosimo Galluzzi
JBB: An Artblog!
祝日 / Permanent Vacation
No title available
occasionally subtle
art blog(derogatory)
Misplaced Lens Cap
tannertan36
let's talk about Bridgerton tea, my ask is open
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#extradirty
tumblr dot com
will byers stan first human second
JVL
wallacepolsom
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dirt enthusiast
🪼
seen from United Kingdom
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seen from Argentina
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seen from T1
seen from South Korea
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@maelace
yall think Davy is still in the navy
it's been 50 years and the mandatory retirement age is 62 so probably not
🫡
Davy we thank you for your service
Can we hope that Paul the real estate novelist found time for a husband?
He and Davy got together after DADT was repealed
Okay but imagine being the team of Eridian scientists tasked with keeping Erid's Only Human alive for as long as possible while the whole planet's environment is literally trying to kill him. And then Rocky shows up and is like:
“Grace says he would like half of dome to be water.”
“Oh, is necessary for humans to have large amounts of water question?”
Small Eridian equivalent of a sigh. “No. Not needed for life. In fact Grace will die if he falls in water and does not get out.”
“Tell him we give him water in containers that won't kill him. Lots lots lots of water on Erid for Grace to drink.”
“No. Grace say he want water on ground. Also want it with excess sodium chloride compound so it will be unhealthy for drink.”
“WHY QUESTION???”
To celebrate Erid getting their sun back on track, Grace asks for some alcohol. There's a small amount left from the Hail Mary and Rocky offers to take it to the science Eridians to see if they can synthesise more.
“Grace want this liquid for celebration.”
“Of course.” They scan it. “You have wrong liquid. This contain compounds which are poisonous for humans.”
“Yes yes yes. Grace say humans like feeling of being slightly poisoned.”
“WHY QUESTION?????”
Grace is like one of those extremely finicky tropical fish who instantly die if not kept in extremely specific conditions.
Only here the fish can talk and keeps asking you to make it vodka.
Let's ambush mama! 😼
"Why do Pallas cats always look grumpy?"
"Pallas kittens."
The sheer roundness of this kitten must be admired.
the thing is that for all its supposed faults, i would take this brand of 90s utopian globalism over whatever the fuck we’ve been doing for the last 10 years in a heartbeat
debates i didn't know existed + a very humorous distinction
hostiles = antagonists that Murderbot is worried about 😳
targets = antagonists that need to worry about Murderbot :)c
For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again
"For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again tomorrow.
That routine just changed.
On March 26, 2026, the U.S. Food and Drug Administration approved Awiqli (insulin icodec-abae), developed by Novo Nordisk, as the first and only once-weekly basal insulin ever approved for adults with type 2 diabetes in the United States.
This is not a minor update to an existing drug.
It is the first entirely new class of basal insulin to reach U.S. patients in more than two decades.
Instead of injecting insulin every single day, people with type 2 diabetes using Awiqli will only need one shot per week, on the same day, every week.
That means reducing from 365 injections a year down to just 52.
For anyone who has ever felt the weight of that daily ritual — the anxiety of forgetting, the physical discomfort, the constant reminder that their body needs help — this approval represents something much bigger than a dosing schedule.
It represents relief.
How the Drug Actually Works
Understanding why this injection lasts a full week requires a quick look inside the body.
Most traditional basal insulins are absorbed into the bloodstream and begin breaking down within 24 hours, which is why patients need a fresh dose every day to maintain stable blood sugar levels.
Awiqli works differently.
Its active ingredient, insulin icodec-abae, is engineered to loosely attach to a blood protein called albumin, which is found naturally and abundantly in the bloodstream.
This attachment creates a slow-release reservoir.
Instead of flooding the system and fading fast, the insulin releases gradually and consistently over an entire seven-day period, keeping blood sugar in a healthy range around the clock...
The FDA reviewed and ultimately declined to approve it for people with type 1 diabetes, citing concerns about a modestly increased risk of hypoglycemia in that population specifically.
Some regulatory agencies in other countries, including the European Union, Canada, Australia, and Japan, have approved Awiqli for both type 1 and type 2 diabetes, but for now the U.S. approval is limited to type 2...
What Comes Next
Awiqli is not standing alone in this space for long.
Eli Lilly is developing its own once-weekly basal insulin, called efsitora alfa, which is currently in late-stage clinical trials.
If that drug also earns FDA approval, it would give patients and doctors two once-weekly options to choose from, allowing for personalized decisions based on a patient’s health profile, insurance coverage, and individual response.
The broader direction of travel in diabetes care is unmistakable.
Fewer injections, smarter formulations, and better integration with digital tools like continuous glucose monitors and insulin-tracking apps are all converging toward a future where managing diabetes requires less daily mental effort without becoming any less medically precise...
A Small Shot With Large Implications
It is easy to look at a once-weekly injection and see only a scheduling change.
But the science behind Awiqli, the scale of the ONWARDS trials, and the consistent satisfaction reported by patients all point toward something that matters far more than convenience.
Diabetes management has always asked a lot of people.
It asks for daily vigilance, daily discipline, and a daily willingness to confront one’s own condition, sometimes in uncomfortable or inconvenient circumstances.
Anything that reduces that load, without reducing the quality of care, is worth taking seriously.
For the more than 37 million Americans living with diabetes, and the hundreds of millions more around the world, a simpler weekly routine could mean the difference between a treatment plan that works on paper and one that actually works in a person’s life.
That is the real significance of what the FDA approved on March 26, 2026.
Not just a new drug.
A new way of keeping people healthy, one week at a time."
-via Science Aim, March 29, 2026.
you don’t realize how important lunch is until you’re wandering around thinking about how unloveable and untalented and uniquely cursed you are and then it’s 4pm and you finally eat lunch and you go Oh. oh right.
lot of people commenting on this post like "who eats lunch at 4pm that's a terrible time to eat lunch" yes. that is the point. 4pm lunch is inadvisable. 4pm lunch is not the ideal. 4pm lunch makes the mind demons real.
i genuinely love that the way k.a applegate resolves the issue of needing the alien on the team to be able to drop plot crumbs without totally solving everything for the human kids is by making aximili-esgarrouth-isthill a jock who only tangentially paid attention to when his teachers were explaining, like, the andalite equivalent of how to find the cosine of a triangle, and now he's in an astronomically rare circumstance where the fate of an entire species depends on him remembering how to do that. and he's cold sweating trying to recall the answers to homework problems he didn't do. and also he's always lying.
ax is literally experiencing like if you got teleported back several hundred years and everyone was expecting you to explain the precise mechanisms of how cell phones work to them and if you don't come up with a sufficient explanation they're all going to die. And he's not enjoying it.
every day this happens to ax
do you have some crazy family lore
yes
no
no but i know someone else's crazy family lore
results
What do you prefer your house thermostat set at, in degrees Celcius?
64 or lower
65-67
68-69
70-72
73 or higher
No preference
What do you prefer your house thermostat set at, in degrees Celcius?
64 or lower
65-67
68-69
70-72
73 or higher
No preference
Shavuot is about the Jewish people signing the Terms & Conditions before reading them.
Every generation, however, gets patch updates and both the user manuals and technical documentation are incredibly detailed.
And excellent user support is available from specialists who have made it their life's work to study the exhaustive documentation.
(And a good Rabbi will never just tell the user to RTFM.)
Chag Shavuot Sameach
the sewing machine is a delicate breed of horse
update: i’ve made it through the user manual and have sewn myself a cravat. the sewing machine is a delicate breed of horse with anger in its motion and spite in its heart.
The last character you wrote about is put in the last video game you played for a week. Can they survive?
The last character you wrote about is put in the last video game you played for a week. Can they survive?
Yes
No
See results
art by Curtis Lanaghan
"The Sorcerer"
I think I'm going to remember this phrase every time I cook for the next five years
A few weeks ago I got really frustrated that the local goodwill I go to every so often had blocked off/closed its public restrooms since the last time I had been there. I'm talking like the bathroom signs had been ripped off and doors barricaded by the furniture section. It bothered me so much I started drawing this on the way home.
I'm currently waiting for my goodies to show up for a bigger store update I'm planning for the end of the month. BUT, since I finished this and can print some stickers from home anyways, I figured, why not share it now?
Have made it available as a sticker you can buy from my ko-fi shop with free shipping! 👽💚💖💙
I like this design so so much i have some things to point out:
Walkable! Includes someone walking with a cane!! Which means every city MUST be walkable ESPECIALLY for people who have difficulties walking. Make the sidewalks wide enough for wheelchairs!!
Also! The green space!! We all need more green space in our cities
Sittable! Someone who is sporty! In athletic clothes! Everybody needs to sit sometimes! Everybody deserves access to seating even if they don't look like they "need" it (appearing able-bodied, fit, young, etc) Furthermore, the bus stop! Which also adds onto the fact that our cities have to have comprehensive and affordable public services and transportation! This alien also has their eyes closed which shows restfulness and safety because cities should also be sleepable btw
Shittable! NO GENDER ON THE BATHROOM SIGN LET'S GOOO. That's a toilet for everybody babyyyyy. And it's wheelchair accessible!!! A toilet for everybody because as the good book says Everybody Poops
Anyways i love this sosososoosso much i have so many emotions abt it rn actually i think this is so beautiful it sums up so much of how i feel thank you
