A lot of people mention that Outer Wilds is an amazing game that is best experienced completely blind but then don't try to elaborate on that. I will elaborate on it while still not spoiling it.
Let's start with why exactly spoilers matter for this game. I am someone who normally doesn't care too much about getting spoiled and can even build anticipation and interest from hearing story spoilers, but there are a couple of areas where I think spoilers definitely matter even for me: Exploration and Mystery.
Outer Wilds is an open world mystery platformer that not only focuses heavily on exploration and mystery, it is easily in the top tier of games I have played for both elements. The system you explore in the game is immaculately crafted and dense, and it quickly introduces several enigmatic things for you to pursue with layered clues that have you venturing around very unique places so you can discover both clues to how to find other clues and also piece together the greater story.
And, notably, the game does not gate your progress by making you accumulate objects or reward progression with items. The one currency you accumulate as you play is knowledge. You have every tool you will ever need from the moment you complete the "tutorial", but there is a lot of information you don't yet have that will be necessary to progress.
(But something else that's pretty cool is that the game is truly open. You can explore any planet or space structure you wish as soon as you launch for the first time, so you can discover clues out of order or even solve certain puzzles without finding the clues for them by getting lucky, experimenting for a while, or being particularly observant).
This is why going in blind matters here. Spoilers for Outer Wilds don't merely ruin a surprise twist, they change how you experience the game on a very fundamental level and somewhat play it for you. This is also why that first playthrough is so different from any subsequent ones, to a much greater degree than with most other games.
The game's objectives are all tied to your own curiosity. You notice strange or interesting things, you feel curious about what is going on with them, you investigate, and your curiosity is both rewarded and expanded. It's pure joy for the part of you that loves to explore and discover.
I know for some people it might be daunting to be thrown into a star system with a handful of (small but dense) planets plus several other objects to look at with no clear objectives, but just give it an hour and you'll probably find your own way, especially if you paid attention at the museum in your home planet.