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btw if a voice in your head tells you not to finish your course of antibiotics that's the MRSA talking and you should definitely listen 💕 flush! those! pills!
writing fic for the pitt is not for the weak because like 99% of the fandom works in healthcare and it feels like being grilled at grand rounds by the whole attending staff tribunal whilst you present your work - your blorbos having wicked sex - and the attendings nod along, but the moment you mention in passing treating a nosocomial staph infection with Cefalexinum and all the eyes turn on you and you know you done fucked up
Boeing’s deliberately defective fleet of flying sky-wreckage
I'm touring my new, nationally bestselling novel The Bezzle! Catch me TOMORROW (May 2) in WINNIPEG, then Calgary (May 3), Vancouver (May 4), Tartu, Estonia, and beyond!
Boeing's 787 "Dreamliner" is manufactured far from the company's Seattle facility, in a non-union shop in Charleston, South Carolina. At that shop, there is a cage full of defective parts that have been pulled from production because they are not airworthy.
Hundreds of parts from that Material Review Segregation Area (MRSA) were secretly pulled from that cage and installed on aircraft that are currently plying the world's skies. Among them, sections 47/48 of a 787 – the last four rows of the plane, along with its galley and rear toilets. As Moe Tkacik writes in her excellent piece on Boeing's lethally corrupt culture of financialization and whistleblower intimidation, this is a big ass chunk of an airplane, and there's no way it could go missing from the MRSA cage without a lot of people knowing about it:
https://prospect.org/infrastructure/transportation/2024-04-30-whistleblower-laws-protect-lawbreakers/
More: MRSA parts are prominently emblazoned with red marks denoting them as defective and unsafe. For a plane to escape Boeing's production line and find its way to a civilian airport near you with these defective parts installed, many people will have to see and ignore this literal red flag.
The MRSA cage was a special concern of John "Swampy" Barnett, the Boeing whistleblower who is alleged to have killed himself in March. Tkacik's earlier profile of Swampy paints a picture of a fearless, stubborn engineer who refused to go along to get along, refused to allow himself to become inured to Boeing's growing culture of profits over safety:
https://prospect.org/infrastructure/transportation/2024-03-28-suicide-mission-boeing/
Boeing is America's last aviation company and its single largest exporter. After the company was allowed to merge with its rival McDonnell-Douglas in 1997, the combined company came under MDD's notoriously financially oriented management culture. MDD CEO Harry Stonecipher became Boeing's CEO in the early 2000s. Stonecipher was a protege of Jack Welch, the man who destroyed General Electric with cuts to quality and workforce and aggressive union-busting, a classic Mafia-style "bust-out" that devoured the company's seed corn and left it a barren wasteland:
https://qz.com/1776080/how-the-mcdonnell-douglas-boeing-merger-led-to-the-737-max-crisis
Post-merger, Boeing became increasingly infected with MDD's culture. The company chased cheap, less-skilled labor to other countries and to America's great onshore-offshore sacrifice zone, the "right-to-work" American south, where bosses can fire uppity workers who balked at criminal orders, without the hassle of a union grievance.
Stonecipher was succeeded by Jim "Prince Jim" McNerney, ex-3M CEO, another Jack Welch protege (Welch spawned a botnet of sociopath looters who seized control of the country's largest, most successful firms, and drove them into the ground). McNerney had a cute name for the company's senior engineers: "phenomenally talented assholes." He created a program to help his managers force these skilled workers – everyone a Boeing who knew how to build a plane – out of the company.
McNerney's big idea was to get rid of "phenomenally talented assholes" and outsource the Dreamliner's design to Boeing's suppliers, who were utterly dependent on the company and could easily be pushed around (McNerney didn't care that most of these companies lacked engineering departments). This resulted in a $80b cost overrun, and a last-minute scramble to save the 787 by shipping a "cleanup crew" from Seattle to South Carolina, in the hopes that those "phenomenally talented assholes" could save McNerney's ass.
Swampy was part of the cleanup crew. He was terrified by what he saw there. Boeing had convinced the FAA to let them company perform its own inspections, replacing independent government inspectors with Boeing employees. The company would mark its own homework, and it swore that it wouldn't cheat.
Boeing cheated. Swampy dutifully reported the legion of safety violations he witnessed and was banished to babysit the MRSA, an assignment his managers viewed as a punishment that would isolate Swampy from the criminality he refused to stop reporting. Instead, Swampy audited the MRSA, and discovered that at least 420 defective aviation components had gone missing from the cage, presumably to be installed in planes that were behind schedule. Swampy then audited the keys to the MRSA and learned that hundreds of keys were "floating around" the Charleston facility. Virtually anyone could liberate a defective part and install it into an airplane without any paper trail.
Staphylococcus aureus
Staphylococcus aureus is a type of bacteria with many known strains that have become resistant to antibiotics. Methicillin resistance (MRSA), vancomycin intermediate resistance (VISA), and vancomycin resistance (VRSA) are some examples of strains that are partially or fully resistant to antibiotics, making them major concerns in hospitals. It's estimated that only 2% of S. aureus strains are sensitive to penicillin antibiotics.
Pore Law
Staph A bacteria causes skin, respiratory and other infections and, due to antibiotic resistance, is a world health threat. They cause cell death with a toxin called α-hemolysin that punches pores in cell membranes. In this study, using red blood cells researchers reveals stepwise the toxin-induced pore formation process providing insight for anti-bacterial drug development
Read the published research article here
Video from work by Arnab Chatterjee and colleagues
Molecular Biophysics Unit, Indian Institute of Science, Bengaluru, India
Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in Journal of Cell Biology, January 2026
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Vancomycin-resistant Staphylococcus aureus
“Staphylococcus aureus colonies on blood agar. Note the golden yellow pigment and beta hemolysis around it.” - via Wikimedia Commons