For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again
"For millions of people managing type 2 diabetes, mornings begin the same way — a needle, a dose, and a quiet mental note to do it all again tomorrow.
That routine just changed.
On March 26, 2026, the U.S. Food and Drug Administration approved Awiqli (insulin icodec-abae), developed by Novo Nordisk, as the first and only once-weekly basal insulin ever approved for adults with type 2 diabetes in the United States.
This is not a minor update to an existing drug.
It is the first entirely new class of basal insulin to reach U.S. patients in more than two decades.
Instead of injecting insulin every single day, people with type 2 diabetes using Awiqli will only need one shot per week, on the same day, every week.
That means reducing from 365 injections a year down to just 52.
For anyone who has ever felt the weight of that daily ritual — the anxiety of forgetting, the physical discomfort, the constant reminder that their body needs help — this approval represents something much bigger than a dosing schedule.
It represents relief.
How the Drug Actually Works
Understanding why this injection lasts a full week requires a quick look inside the body.
Most traditional basal insulins are absorbed into the bloodstream and begin breaking down within 24 hours, which is why patients need a fresh dose every day to maintain stable blood sugar levels.
Awiqli works differently.
Its active ingredient, insulin icodec-abae, is engineered to loosely attach to a blood protein called albumin, which is found naturally and abundantly in the bloodstream.
This attachment creates a slow-release reservoir.
Instead of flooding the system and fading fast, the insulin releases gradually and consistently over an entire seven-day period, keeping blood sugar in a healthy range around the clock...
The FDA reviewed and ultimately declined to approve it for people with type 1 diabetes, citing concerns about a modestly increased risk of hypoglycemia in that population specifically.
Some regulatory agencies in other countries, including the European Union, Canada, Australia, and Japan, have approved Awiqli for both type 1 and type 2 diabetes, but for now the U.S. approval is limited to type 2...
What Comes Next
Awiqli is not standing alone in this space for long.
Eli Lilly is developing its own once-weekly basal insulin, called efsitora alfa, which is currently in late-stage clinical trials.
If that drug also earns FDA approval, it would give patients and doctors two once-weekly options to choose from, allowing for personalized decisions based on a patient’s health profile, insurance coverage, and individual response.
The broader direction of travel in diabetes care is unmistakable.
Fewer injections, smarter formulations, and better integration with digital tools like continuous glucose monitors and insulin-tracking apps are all converging toward a future where managing diabetes requires less daily mental effort without becoming any less medically precise...
A Small Shot With Large Implications
It is easy to look at a once-weekly injection and see only a scheduling change.
But the science behind Awiqli, the scale of the ONWARDS trials, and the consistent satisfaction reported by patients all point toward something that matters far more than convenience.
Diabetes management has always asked a lot of people.
It asks for daily vigilance, daily discipline, and a daily willingness to confront one’s own condition, sometimes in uncomfortable or inconvenient circumstances.
Anything that reduces that load, without reducing the quality of care, is worth taking seriously.
For the more than 37 million Americans living with diabetes, and the hundreds of millions more around the world, a simpler weekly routine could mean the difference between a treatment plan that works on paper and one that actually works in a person’s life.
That is the real significance of what the FDA approved on March 26, 2026.
Not just a new drug.
A new way of keeping people healthy, one week at a time."
I was thinking of reblogging this again just because the original video is still amazing, but then I see the second video and lost my mind. The upgraded fan, the body glitter, the sheer fact that he got to do this with the actual singer.
I need a fic where Hayden’s youngest, Amber Pike, is Shane’s flavor of autistic, and as soon as they realize, Ilya is like, oh, step aside, I’ve got this.
Like, he’s generally fab with kids anyway but he has a near lifetime of knowledge figuring out what makes Shane tick (and twitch) and this is just a child who isn’t able to control their environment or modulate their responses to things in the way that Shane can.
So when they’re having dinner with the Pikes and Jackie is tiredly recounting the ongoing process of getting Amber tested and how lost they’re feeling, Ilya is like, oh, I have been training my whole life for this. And when 3yr old Amber inevitably starts having a meltdown, Ilya jumps up and says, “Here. I will fix. You stay.”
And they’re like, you know what, sure, have at it.
Within a few minutes of Ilya disappearing with Amber, the crying stops. When they track the two down a half hour later, they’re in the basement on the rug with all the lights off. Amber is wearing a pair of Christmas Pjs (notably a bamboo/cotton mix) despite the fact that it’s February, and she’s laying on Ilya’s chest, ear to his sternum, alternating tapping along as he hums, spinning his ring on his finger, and rubbing his shirt (also a Nice Fabric since obviously Ilya’s whole wardrobe is Shane-approved).
And when Amber sees the family + Shane trooping down the stairs and starts to get riled up again, Ilya is immediately like, “Turn off hall light. It is Dark Floor Time. Only quiet people allowed to join, okie?” And Amber lets out this relieved, shuddery little breath because she has someone who understands and can advocate for her which nearly ends Ilya’s life but also Shane is like, oh shit, yeah, I’m the the best at floor time, I love being quiet and grounded and aimlessly touching my husband, lets fucking go.
So even when the other Pike children get antsy after a few minutes, and their parents take them upstairs, Shane and Ilya stay, letting Amber crawl all over them and get chill before they get her ready for bed.
Afterward, Ilya gives Hayden and Jackie an exhaustive rundown of all the various things they might want to consider for clothing and food and overstimulation and regulation and they’re very grateful but Shane is listening to this going, okay some of this I obviously knew about myself but some of these things I didn’t even notice? Holy shit? He pays such close attention to me?? Hold on, some of these things I haven’t done since middle school. Ilya, did you talk to my mom about my childhood behavior?? And yes, Ilya gives Jackie Yuna’s phone number for additional consult until they get Amber’s official diagnosis and are provided with more resources.
(And maybe at first Shane wants to be annoyed about the fact that Ilya has been, what, researching and compiling some sort of manual on how to handle him? Right up until Ilya reminds Shane that Shane has an Ilya Spreadsheet that now contains over a dozen tabs of Ilya’s likes and dislikes, injuries and recovery protocols, training and diet and supplements, depression treatment with behavioral red-flags and mitigation techniques, and even sexual preferences. And Shane is like, oh yeah, okay, that’s fair)
But anyway. As the Pike kids grow up, Ilya tries not to be obvious about it, but it’s just Known that Amber is Uncle Ilya’s favorite. And everyone is mostly okay with that.
His doting is so quietly impactful for Shane, though, because here is a child who reminds Shane of his own younger self: a little odd, who struggles to articulate what she feels and needs, who gets overstimulated easily and has obsessive interests, but even so, Amber is a favorite and so loved and accommodated by his husband. That’s gotta be healing.
Also, as much as they try to get Amber to hyperfixate on hockey, I think it’d be hilarious if she became a horse girl and Ilya literally buys her a pony.
(Hayden: Oh my god, Ilya. Do you know how expensive horses are??
Ilya: Yes, yes, maybe for 15th best player on the Metros with one hundred other children, horse is big cost, but not for best player in the league married to second best player in the league with Yuna Hollander in charge of sponsorship deals. I set up fund for board and train. Is couch money.)
(Shane is unavailable for comment because he is feeling a velvety horse nose for the first time and realizing that maybe he is also a horse girl).
It's 32°C today, so have a refreshing new Paranatellonta video!
Rabbit's Restaurant was the 152nd edition from July 2016. Almost 10 years old!
Rather read it in text form? Find the original Tumblr post here.
Also want to hear it in Dutch? All my translations come out of my own brain and are read into a microphone by my own voice, no AI involved. Watch the Dutch video here.
Art for the amazing @zenaidamacrouras1's Hollanov AU fic Untouchable Face. Thank you for being such a good friend and supporter, Z.
He stands at the water’s edge and scans the beach, which has a few people lying on the chairs provided by the hotel, a family under an umbrella with some kids digging in the sand, and, unmistakably, Ilya Rozanov wearing a black swimsuit and a gold Rolex, walking toward him.
So, Shane successfully negotiated Ilya out of any props for this photoshoot, and he stands by that, but now wardrobe has taken things to the other extreme: Ilya is currently sauntering from the makeup tent to a section of beach framed by aesthetic rocks on one side and a wall of light reflector umbrellas on the other, and he’s wearing only a watch.
Okay, he also has on very small, black, silky briefs.
Please do not repost my work without permission
Photoshop elements (where photoshop is used as the verb), overlays, overlines, textures... I had a lot of fun with these!
Just realized that the reason I love making friends on tumblr is because it’s exactly how you make friends on the playground as a six year old. No, I don’t know their name but they love mermaids too and built this awesome sand castle. No, I don’t know their age but their imaginary cheetah is friends with mine. You like this show? You like this character?? You can sing the theme song really loud??? Here is a flower crown. Here is a juice box. You can share my time and I might never see you again but part of you stays in my soul forever. In my mind we’re still on the swing set and the sky is blue and nothing will ever be wrong again.
I fully believe that Shane and Ilya cannot agree on an anniversary. Shane says it was the All Stars weekend because that's when he thought they were both 100% serious about the relationship because that's when he was, Ilya says it was the cottage when they said "I love you'' because he didn't believe in it until that moment. They find this out the first year with Shane's anniversary date when Shane plans an elaborate secret date the last night of All Stars and gets Ilya gifts, and Ilya has no idea what its for. They agree to disagree on the date, "We will just celebrate twice a year, I guess." It happens again with their wedding anniversary, Shane says its when they legally got married, Ilya says it was when the twins married them because he doesnt care about about being officially married in the eyes of Canadian law he cares about the first time they said "I do". They find this out when a reporter asks them about their wedding and when they had it and they both gave different answers. Once again they agree to just celebrate twice a year. They say it is because the date doesn't really matter and both of them are right in some way, but in reality it is so they can compete on who plans the more romantic, thoughtful, and elaborate anniversary date. And so that they don't fight about who's planning the date this year or making conflicting plans by accident.
murderbot and arts first meeting is literally so funny. like imagine you meet a biblically accurate angel and instead of being all 'be not afraid' it says actually you SHOULD be afraid. and then when you are in fact afraid it goes oh shit oh fuck. not THAT afraid, sorry. wanna watch tv? and then you watch tv with it and it keeps telling you to pause it when its favourite characters are in danger so it can calm down. and then it asks to do surgery on your bones. Asshole Research Transport character of all time
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