Transfemme Spidey where she transitions in costume first, debuting as "Your friendly neighborhood Spiderwoman". It's NYC so this is mostly received either positively or without much notice. New Yorker don't really give a damn who they gotta fight if it's a fight.
Jonah remains oddly silent on the issue.
Parker, however, eventually works up the need to transition in her civvy life and comes out at work as Emily. The Bugle crew are happy and supportive, but she gets called into Jameson's office.
"This is because of her, isn't it?"
"The Spider! This transition thing you're doing, it's because of her, isn't it? I know you're close; this is her doing, isn't it?”
"Whatever. I'm... Grateful to her."
"Parker, you've been a miserable worm since I met you. I've seen you smile more this week than in the past five years put together. So... Tell her I appreciate that she gave you the courage."
Emily's eyes water. "Yes, sir."
"But if you tell anyone else, you're fired! Now get out there and get me better photos! Out!"