Wolfgirl, but puppy

Gay and trans, 20-something, cuted with the paws :3. 18+.

[bloodraven55]

remembered this very appropriate line for june

[industrial--honey]

I wish more people knew how progesterone works (as a psychoactive). So I'm just gonna talk a little bit about that. Consider this a little harm reduction guide to my most-used substance. I have done doses ranging from 200mg to 4800mg and everything in between.

I will be speaking as though this is a recreational psychoactive substance. So for the purposes of this post, the breast growth? That's considered a side effect.

Reblogging this post for reach would be appreciated, as this substance is extremely common with a very specific group of people (hi, dolls. ily). And even if you're not using it recreationally, it's still good to know how a drug works and what it does to you.

Disclaimer: I am not a medical professional. This is not medical advice My sources are psychonautwiki, wikipedia, and the sources linked on those pages. As well as my own experience having experimented with and abused this substance recreationally for about a year. I won't be delving into the chemistry and pharmacology of progesterone, but information on GABAergic substances is readily available. I strongly suggest you do your own research in addition to reading this post.

Progesterone (Pregn-4-ene-3,20-dione) is a steroid with depressant effects. Progesterone itself is not psychoactive. However, the body metabolizes progesterone into a handful of GABAergic molecules (allopregnanolone, pregnanolone, isopregnanolone, epipregnanolone). This means progesterone is a prodrug for these metabolites. This happens in the liver and these metabolites are the cause of the high. Progesterone is fat soluble. So eating fatty foods before will increase the potency of progesterone significantly. From my own experimentation, I have found this to be a roughly two-fold increase in potency. Because progesterone is GABAergic, it is recommended to avoid other GABAergic substances (alcohol, benzodiazepines, opiates, gabapentinoids, etc) while using progesterone. Mixing these carries a significant risk of overdose.

Common Effects of Progesterone: Sedation, loss of motor control, pain relief, anxiety suppression, disinhibition, dizziness, euphoria, increased libido, and amnesia. These effects increase with dose. I find disinhibition, amnesia, and loss of motor control to increase significantly at higher doses, when compared to the other effects. Because progesterone is also a hormone, recreationally using progesterone can have hormonal side effects, including premenstrual syndrome.

Dosage: A common, prescribed dosage of progesterone ranges from 100mg to 400mg. A common recreational dosage will range from 200mg to over 1000mg, depending on the desired strength of the experience. 200mg is considered a "common" recreational dose, 400mg is a "strong" dose, and 600mg+ is a "heavy" dose. Dosages are dependent on the person dosing, everyone's body will react differently to substances. Start at a low dose to avoid undesirable effects. You know yourself best. Keep in mind that eating before your dose means a potentiated experience, and a higher/potentiated dose always means higher risk of undesirable effects, including overdose! While severe and fatal overdoses are uncommon with progesterone, it is still important to be cognizant of the risk. Especially when using other substances. Progesterone overdose can manifest as blacking out, respiratory depression, and/or sudden and immediate loss of consciousness (I have lost consciousness while standing up on as little as 600mg of progesterone. This led to me falling over and getting a concussion).

Tolerance: Progesterone tolerance builds very quickly When using recreationally, I have found it helpful to skip a couple days between doses. This is to allow ones tolerance to get closer to baseline, to minimize potential of an overdose, and to minimize the hormonal side effects. This is recommended with similar substances, such as gabapentin/pregabalin and benzodiazepines.

Dependence, Addiction, and Withdrawals: There are few reported cases of progesterone dependence and/or addiction. However I have found that I have become dependent on progesterone to be able to sleep (though this is partially because I use it to self medicate my insomnia). And I do consider myself to be addicted to progesterone. Withdrawal symptoms (for me) include body aches, trouble sleeping, compulsions to use, irritability, and emotional dysregulation. Skipping days when using recreationally will help minimize the potential of dependence and addiction, but the risk is never zero.

Routes of Administration (RoA): The two common RoAs are orally and rectally. These will have differing intensities, primarily due to the rectal RoA bypassing the liver to a certain degree, when compared to taking it orally. This is why people often take progesterone rectally if they want to avoid or minimize the psychoactive effects. However, the hormonal bioavailability of progesterone, when taken rectally, is higher (due to less of the molecule being metabolized in the liver). So that RoA can be desirable for those reasons.

What you can Expect: I will be talking from personal experience here. Your experiences will be different. 200mg: A typical therapeutic dose for feminizing hormone replacement therapy. I take this nightly. The effects are light, but I notice myself being more social and less anxious. I have not blacked out when using this dose. 400mg: This is my typical social dose. It allows me to be social and not anxious while still allowing me to feel confident to use other substances during these experiences. The pain relief is very noticeable at this dose and I am able to sleep very easily when not in a social setting. I find that this is where blacking out becomes a possibility for me, especially if I have eaten well. 600mg: This is where I start to avoid using other substances. Euphoria, disinhibition, and increased libido are very strong here. Blacking out is common for me at this dose 800mg: Blacking out happens quickly and I will almost certainly lose consciousness at this dose. This is not a dose I use socially for these reasons. At this dose, my tolerance the next day is extremely high and I do not get desirable effects unless I use 800mg+. The chance for blacking out remains the same even though the desirable effects are weak. 1200mg: I black out and lose consciousness within about 30 minutes of the come-up. I have used this dose to fall asleep when I am struggling with more severe insomnia. 4800mg: Full disclosure, this was a suicide attempt. However progesterone isn't great for that. I found myself conscious well into the peak of the experience, likely due to my extremely distressed state. I, surprisingly, did not black out. I believe this is because progesterone's metabolites may have a bioavailability inversely proportional to the dose (similar to gabapentin) in addition to my emotional state. Do not quote me on this, I could not find a source to back this up.

All in all, progesterone is a fun recreational substance with significant and very impactful downsides. I cannot recommend using it recreationally. However, if you choose to explore this substance in a recreational way, I hope this post helps you make a more informed decision. And please take it upon yourself to do additional research into this substance before you use.

Remember, there is no safe drug use. Only safer drug use

~ industrial honey

[industrial--honey]

@ prev re: rectal administration (boofing): this is also because progesterone has reduced bioavailability when taken rectally. less of the drug is metabolized in the liver, so less of it is metabolizes into the psychoactive compounds. so you will feel resuced psychoactive effects

im also gonna use this opportunity to elaborate on the differences between rectal and oral administration, so heres something i sent to a friend who asked for additional information on this:

once again i will be speaking as though this is purely a recreational substance. eg, speaking about how to best take it as a recreational substance. so hormonal bioavailability is a side effect, though i will still touch on it

oral:

- assuming an empty stomach and an unpunctured capsule, it will take roughly 30-60 minutes for the drug to start entering your bloodstream. eating can increase the time it takes for the drug to enter your bloodstream by up to 4 hours

rectal/boofing:

- proper technique:

- - for best results, evacuate your bowels (either via bowel movement or douching). some people recommend poking a hole in the capsule (i have not tried this as the oral bioavailability is higher regardless) this helps the drug escape from the capsule faster and will, in turn, allow the drug to ender the bloodstream sooner. insert the capsule about 2-6cm past the anus (the specific depth depends on your individual biology). this is in an area called the "anal columns". these structures are mucous membranes and have a lot of bloodflow. if you push it in too far you will start to enter the intestines, at which point the bioavailability, absorbtion rate, and effects will be more similar to the oral RoA

- this RoA will allow the drug to enter your blood stream much quicker than when taken orally. potentially minutes instead of an hour. after the capsule dissolves, more of the drug is immediately entering the bloodstream, and less of it is metabolized through the liver. this means it will have reduced potency of psychoactive effects. however it will have a higher hormonal bioavailability. this will manifest as reduced psychoactive effects

~ industrial honey

[caffichai]

Rushour Crush

Commission for @esmekipomi!

[doomedmybeloved]

Them cryptids 😰💚🧡

Based on this tweet:

[fertilefloor]

look how long my hair is getting yay

[milf--adjacent]

Thing that has dawned on me recently that I still don't have the words to correctly express: With all the anti-TMA/TME transmisogynists coming out of the woodwork to tell me I hate queer people over the past few days, a pattern has emerged in the background. The idea that "binary bad" and "people don't fit in boxes" keeps coming up in regards to *checks notes* trans womanhood, and it's like... Some people absolutely do fit into a box? Does me having fought for years to become the queer woman I am today make me inherently bad because I'm not "genderfuck" enough about it? Is me being a lesbian somehow evil because I do that instead of being bi? The way some of these people place a moral value on people inhabiting in-between spaces or broad categories gets my abuse detectors from jr high chirping in my brain, like these people want to hurt you because of who you are. This is the part where I don't have good words, as you can see, but they treat binaries in general as the enemy, not the economically and socially enforced based-in-white-supremacy stock-standard gender binary proped up by western society. They treat me as the enemy because I am a she/her woman who would like to be called ma'am at the grocery store instead of just dying inside as a "feminine man" who better fits their holy ideal of gender flux. "Binaries" in general are not the enemy, a specific harmful binary which is tied to how society treats you is. My being a "binary trans woman" (and fuck do I hate that term) doesn't magically gift me with cis-woman priviliges or something. In fact, it frequently opens me up to gendered harassment from other queer people who think my existence is the transfeminine version of tradwifing.

That is to say, again, that the idea of binaries (e.g. yin and yang, two halves of a whole, man and woman, gay and straight) is not the enemy, a white supremacist society weaponinzing categories against people is.

And that's not even getting into how transmisogyny affected/transmisogyny exempt isn't actually anything close to a binary since it describes a smaller in group affected by specific axes of oppression and a much larger group of people who don't experince those specific axes of oppression.

[milf--adjacent]

You can take pride in your non-binarism, sure, but stop acting like it's a virtue.

[actionpainting-deactivated20231]

my nephews lunch that he packed

[rnelodyy]

[ID: A lunchbox containing a handful of loose lettuce and a half-empty bottle of Pepsi.]

[puppygirllaika]

that's arugula

[ceo-of-lesbians]

[ID: A lunchbox containing a handful of loose lettuce and a half-empty bottle of arugula]

[hellsitegenetics]

String identified: c tat ac [: A c ctag a a ttc a a a-t tt .] tat' aga [: A c ctag a a ttc a a a-t tt aga]

Closest match: Polygonum aviculare genome assembly, chromosome: 2 Common name: Prostrate Knotweed

(image source)

[lasagna-of-loathing]

thats arugula

[hellsitegenetics]

String identified: c tat ac [: A c ctag a a ttc a a a-t tt .] tat' aga [: A c ctag a a ttc a a a-t tt aga]

Closest match: Arugula

[odibatoraso]

[reluctantlybouncingonit]

Speaking from experience, sex can just be this for a while, clothes and all

[im-mender]

hip slam is common play behavior

[gumi-megpoidd]

guh, y'know that feeling when you destroy an enemy heat signature? ffuuuuckk...., mmmpphhgggg~

who let the hounds out in here theyre being perverts again

[dapper-lil-arts]

Rarity after her tenth unicorn foal: “I was expecting to have more Earth ponies given how strong those genes are from Applejack.”

Applejack is just standing in what used to be one of the barns after one of her daughters blew it apart with a magic sneeze: “I think those genes are showing up in other ways…Enterprise! Put down your uncle’s shed this instant!”

Just Applejack’s monstrous strength manifesting in her kids in different ways while they all have a much better natural sense of fashion from Rarity.

Suddenly it now makes sense. RD’s newfound ability to smell when Rarity is pregnant is her version of Pinkie Sense. It is telling her that danger is approaching…in however long MLP ponies are pregnant for. (Some go human time while others do horse and it is one of those questions that may never have an official answer especially since we don’t know when any of the foals that are born over the course of the series are born.)

The idea of rarijack kids being like. Either the most beautiful and on fleek farmers or the most stud handsome fashionistas is endlessly amusing to me tbh. Their two passions and crazy genes mixin together.

Having wild magic unicorns would be very amusing tbh. Ive been told that apple babies are LARGE so thats cute.

[girutea]

青空絵。俺と撫荒さんのほかに誰が喜ぶのか�… on Twitpic

[primiera]

if tentacles are so good why are there not eleventacles?

[primiera]

6 seventacles

[ssnapdragonss]

by @yr_aimt (aimitsu/ibityuttyu)

[deltaomicronfive]

Can anyone help a black transfem with tech and stability for my teaching job? I only owe 250 in rent and need help with procuring a good computer. If I had to set a goal myself it would 750 for other bills and tech by August, when my class starts.

Please please consider helping me out financially to get my best foot forward as a small time educator. Thank you.

Current Goal: 0/750

Link to a post with all my pay apps and gfm info below:

Tumblr is a place to express yourself, discover yourself, and bond over the stuff you love. It's where your interests connect you with your

[deltaomicronfive]

160/750‼️

So many notes, so little help.

Please consider helping me procure the computer on my wish list and pay my 124 electric bill due next week 🙏🏾

[gynoidwren]

Every girl like me I know feels like she was born with an expiration date, like there’s a number stamped on her forehead that says “26 years old” that says “six months after the money runs out” that says “when you can’t do this anymore” that says “as soon as you work up the courage,” and I’m one of the lucky ones, because that scares me, Sometimes I think I have an immigrant’s patriotism for this world, because it took me 20 years to decide that I wanted to live in it. Maybe that’s what hope is.

But I don’t know how to say that the greatest poet I know and her girlfriend, who looks so like me she nearly made my mom faint when she opened the door, are probably not going to last another year. So everybody told me to vote for Bernie Sanders. It’s not enough.

Now people are saying this might be the end times, but I want to remind them that we have already been living in them, for as long as I can remember, and I don’t know why it’s so hard to keep in contact with someone I don’t see, to reach out across that burden of distance with the uncertain arms of exhaustion, but I know why it’s hard to reassure somebody, when all you can say is “I’m scared, too.” How much money do you give somebody, when money is the thing you don’t have? For time, same question.

A trans woman I had never met came into my shop one day and pointed me out to her friend, she said “you are my sister,” and I said “yes, I am.” So when I saw one of my sisters out on the street with a slice of cardboard, I brought her a bottle of water and all the cash I had in my wallet, because afterward I couldn’t stop crying for six hours, and I don’t think anybody asked me why.

Maybe this is why there are so few things that feel important to me anymore. I said “the only things people like me make are cries for help” and I got 128 reblogs. Apparently, some people find that relatable.

A lot of people have told me that I’m the most optimistic person they know, and I don’t tell them that I have to be, I take it as a compliment.

The thing they don’t tell you about hope is that it’s cyclical, it needs to be refreshed every single day, Hope is just like every other kind of work you do on your body. So what does a story mean, to that? What can a poem mean, to that? I abhor maintenance. I don’t want to have to say anything anymore, I want to walk to the place where all my words are done, And build a home there. It’s not enough. All your pleas and all your promises, your fights and feats and failures, are not and never will be enough. Not for us. This world was not made for us.

So let’s build a better one. Let’s start right here, right now, just us, not with a kiss or a fist but just you and me pledging to not let go no matter what comes, deciding even when the love is gone that we’re not gonna let each other drown anymore. So I want to offer my hand, to every girl like me who needs it, and walk with you into a place beyond these empires, a place that doesn’t exist yet. And that, I hope, is enough. Because that’s…everything.

[traaansfem]

The esoteric and nuanced sadist dyke has applied deodorant and thrown on a long sleeve shirt before your date.

[traaansfem]

This is a new and cruel form of denial play, I think :P

[traaansfem]

Of course the pitsniffer blogs found this. I want you to know that this is sadism about that specifically. I think it's really hot, and the degradation of it is really fun to inflict on desperate lasses huffing our smell- but also, having them degrade themselves for that, and getting no reward? That crushed face of betrayal does things for us! >;3