Maybe this is a dumb way of thinking about it, but the Andromeda Galaxy is about 2.5 million light years away, while the edge of the observable universe is about 46.5 billion light years away, which is only 18,600 times further. That's a lot obviously, and it makes a bigger difference when considering the volume of a sphere, but in cosmic terms one thing being only 20k times further away than another is way more graspable than a lot of the numbers you have to work with. (And while obviously Andromeda itself is ungraspably far away, relative to the size of the Milky Way it's not that far either.)
I guess the alternate way of looking at this is that in terms of like the factors of ten scale of the universe, most of the empty (macroscopic) space exists between stars rather than at the largest scales
does that suggest that if you can navigate the galaxy, getting to another galaxy isn't such a stretch? but navigating the galaxy is already crazy hard.
All those observable galaxies might not be there anymore. They could have disappeared a few billion years back and we'd never know.
Heck, Alpha Centauri could have exploded four years ago and we'd not know it yet.
dammit, the good real estate is slipping over the event horizon before we can get there!

















