Nickels And Knackels

She/her

[fashion-runways]

ROBERT WUN Couture Fall/Winter 2027 pls help me get out of debt donating to: ko-fi.com/fashionrunways or dinahlance-shop.fourthwall.com

[tangerineannatto]

Snooze 💤

[aimlessly-wondering-the-internet]

Exalted Eva (If those weavers had succeeded in their supplantation)

[carp-al-tunnel]

me when my daughter winry rockbell 💞💞💞🎀🎀🌸🌸

[kyoterii]

stars are washing ashore 🌌

[inkjie]

soliloquy by an immortal cave painter.

pencil, ink, and ochre on paper

[boombams]

litany in which certain things are crossed out

[blackkatdraws]

[ORV] No more daddy's little girl

Song: You're A Big Girl Now | The Stylistics

[macgyvermedical]

When Drugs Became Available

Have you ever been writing some historical fiction and wondered "hey, I wonder if my characters would have been able to pop an ibuprofen in 1977?" Well, you're in luck, because this post is all about when common medications became available:

Acetaminophen: 1950

Albuterol: 1969 (UK) 1982 (US)

Allopurinol: 1966

Alprazolam: 1981

Amitriptyline: 1961

Amlodipine: 1990

Amoxicilin: 1972

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Apixiban: 2012

Aripiprazole: 2002

Aspirin (first NSAID): 1899

Azidothymidine (first antiviral): 1987

Barbital (first barbiturate): 1903

Bupropion: 1985

Buspirone: 1986

Calcium Carbonate (TUMS): 1930

Captopril (first ACE inhibitor): 1981

Chlordiazepoxide (first benzodiazepine): 1960

Chlorothiazide (first thiazide diuretic): 1957

Chlorpromazine (first antipsychotic): 1952

Cyclobenzeprine: 1977

Diphenhydramine: 1946

Furosemide: 1959

Fluoxetine (first SSRI): 1988

Gabapentin: 1993

Glipizide: 1984

Hydrochlorothiazide: 1959

Ibuprofen: 1969 (UK) 1974 (US)

Insulin: 1923 (though many types of insulins would become available over the next century)

Imipramine (first tricyclic antidepressant): 1959

Iproniazid (first antidepressant (MAOI)): 1952

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Lisinopril: 1987

Lithium: 1949

Losartan (first ARB): 1995

Lovastatin (first statin): 1987

Naproxen: 1976 (Rx) 1990 (OTC)

Nitrogen Mustard (first chemotherapy agent): early 1940's

Methotrexate: 1947

Methylphenidate: 1954

Metformin: 1957 (France) 1995 (US)

Metoprolol: 1978

Montelukast: 1998

Morphine: early 1800's

Omeprazole: 1989

Penicillin: 1945

Phenbezamine (first antihistamine): 1942

Prednisone: 1955

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Sertraline: 1990

Spironolactone: 1959

Sulfanilamide (first modern antibiotic): 1935

Tolbutamide (first oral anti-diabetic drug): 1956

Tramadol: 1977 (Germany) 1995 (US)

Trazodone: 1981

Valacyclovir: 1995

Verapamil (first calcium channel blocker): 1964

Warfarin: 1954

Zopiclone (first "Z-drug"): 1986

[macgyvermedical]

Someone asked for this list in date order, so here it is!

Morphine: early 1800's

Aspirin (first NSAID): 1899

Barbital (first barbiturate): 1903

Insulin: 1923 (though many types of insulins would become available over the next century)

Levothyroxine: 1927 (though desiccated pork thyroid was used for the same reasons as early as 1890)

Calcium Carbonate (TUMS): 1930

Sulfanilamide (first modern antibiotic): 1935

Nitrogen Mustard (first chemotherapy agent): early 1940's

Phenbezamine (first antihistamine): 1942

Penicillin: 1945

Diphenhydramine: 1946

Methotrexate: 1947

Lithium: 1949

Acetaminophen: 1950

Chlorpromazine (first antipsychotic): 1952

Iproniazid (first antidepressant (MAOI)): 1952

Methylphenidate: 1954

Warfarin: 1954

Prednisone: 1955

Tolbutamide (first oral anti-diabetic drug): 1956

Chlorothiazide (first thiazide diuretic): 1957

Metformin: 1957 (France) 1995 (US)

Furosemide: 1959

Hydrochlorothiazide: 1959

Spironolactone: 1959

Imipramine (first tricyclic antidepressant): 1959

Chlordiazepoxide (first benzodiazepine): 1960

Amitriptyline: 1961

Verapamil (first calcium channel blocker): 1964

Propranolol (first beta blocker): 1965 (UK) 1967 (US)

Allopurinol: 1966

Albuterol: 1969 (UK) 1982 (US)

Ibuprofen: 1969 (UK) 1974 (US)

Amoxicilin: 1972

Naproxen: 1976 (Rx) 1990 (OTC)

Cyclobenzeprine: 1977

Tramadol: 1977 (Germany) 1995 (US)

Metoprolol: 1978

Captopril (first ACE inhibitor): 1981

Trazodone: 1981

Alprazolam: 1981

Glipizide: 1984

Bupropion: 1985

Buspirone: 1986

Zopiclone (first "Z-drug"): 1986

Lovastatin (first statin): 1987

Azidothymidine (first antiviral): 1987

Lisinopril: 1987

Fluoxetine (first SSRI): 1988

Omeprazole: 1989

Amlodipine: 1990

Sertraline: 1990

Gabapentin: 1993

Losartan (first ARB): 1995

Valacyclovir: 1995

Amphetamine/Dextroamphetamine (together as Adderall): 1996

Montelukast: 1998

Aripiprazole: 2002

Apixiban: 2012

[eisenkrahe]

I already keep track of a lot of this stuff but hey, it's useful.

[smoke-in-the-winds]

I think it would be fun to go full out with “1001 Arabian Nights” orientalized fictional New York setting. It’s somehow always the 20s, and 80s and also contemporary. There’s depression era gangsters and Wall Street finance bros. Spider-man or the Teen Aged Mutant Ninja Turtles might show up. The Mayor is never named but is a constantly felt presence. Sometimes the World Trade Centres are there, sometimes they’re not.

[importantangeldefendor]

Batman the animated series

[saszor]

[ID in alt text]

"Tutorial" on how to draw an OC with dwarfism (well, some of it).

Boring tired disclaimer: Keep in mind that this is an introductory "drawing" "tutorial" and has some generalizations in it, so not every “X is Z” statement will be true for Actual People. Which happens to be true for everything in general.

You are heavily encouraged to do your own research because this does not contain everything you should know before making a character with any type of dwarfism.

Consider supporting me on ko-fi if you find this to be helpful.

If (when) you repost this on pinterest at least put a link to the original post somewhere..

[sixofclovers]

they're only allowed to play chase when it rains

[tyzulapropagandist]

still my favorite atla take ive seen

[voidsetup1]

nothing here to run from

[shhawwww]

Thumbs up Baby 👎👎👎

[wildragon]

Simon

[saltoncity]

“i love how we as a fandom have just agreed that–” don’t include me in this. do NOT lump me in with that.