Happy Smallpox Eradication Day!
On May 8th, 1980, smallpox was declared eradicated. Meaning there is no natural spread of smallpox anywhere in the world.
Smallpox infections date back at least 3,000 years. There are smallpox scars on the Egyptian pharaoh Ramses V.
The last documented person to have naturally contracted smallpox was 23-year-old hospital cook Ali Maow Maalin, who survived the disease in October of 1977.
The last person to die of the disease was 40-year-old medical photographer Janet Parker, infected in a lab accident in the summer of 1978.
Smallpox was a terrifying disease. It was horrifically painful and killed 1/3 of the people it infected, leaving the rest badly scarred.
We got lucky with smallpox. It had no animal reservoir. Being that it only infected humans we were able to vaccinate our way to eradication.
Today variola major, the virus that causes smallpox, officially exists in 2 places: the CDC in Atlanta, Georgia, USA, and the Vector Institute, Koltsovo, Russia. It is likely that many other countries have samples as well.
Deliberate infection with cowpox to prevent smallpox was the first effective vaccine. We owe every other vaccine to this one breakthrough.
The smallpox vaccine causes a scar at the injection site. You probably know someone with a smallpox vaccine scar. Routine childhood vaccination for smallpox ended in 1972 in the USA.
We used the smallpox vaccine to vaccinate against mpox in 2022. Because of this, I have given the smallpox vaccine. We also vaccinate researchers and others at high risk.
Be grateful you live in a world that does not contain naturally spreading smallpox. It has a long and awful history.


















