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The stuff of screams

The stuff of screams: new blog post on recent work by Luc Arnal and @davidpoeppel @nyuniversity @unige_en

The definitive version of this post was originally published on September 6, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

The tone of this post and the interview are a little different from my usual pieces. Heartfelt thanks to Luc Arnal, who went out of his way to answer my questions, serious and otherwise!

Luc Arnal, a post-doctoral scientist in David Poeppel’s…

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#alarm signals #alarm sounds #amygdala #auditory system #fear #functional MRI #music #psychophysics #screams

The brain’s ebb and flow cares not for distance

The definitive version of this post was originally published on July 29, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

Over the past decade, functional neuroimaging has revealed that our brains go through ever-changing patterns of activity, whether we are active or at rest, healthy or sick, under legal medication or high on illegal drugs. Yet this dynamic…

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#functional connectivity #functional MRI #large-scale neural network #magnetoencephalography #positron emission tomography #resting-state

Here be values (in the brain): how the ventral striatum participates in decision-making

The definitive version of this post was originally published on June 30, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

How do we make decisions? The question is of huge importance for every aspect of our lives. Research into the neuronal mechanisms underlying decision-making has made considerable progress in recent years, from basic research in animal models…

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#choice #decision making #monkeys #reward #single unit activity #value #ventral striatum #ventromedial prefrontal cortex

Improving memory through deep brain stimulation: the very first steps

The definitive version of this post was originally published on June 5, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

Deep brain stimulation (DBS) has been one of the biggest success stories of clinical neuroscience, thanks to its ability to reverse the symptoms of tremors, Parkinson’s disease, and a growing number of neurological and psychiatric conditions without…

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#deep brain stimulation #fornix #hippocampus #intracranial electrodes #memory #memory improvement #neuromodulation #nootropics #visual-spatial memory

From Broca's area to Broca's aphasia: a tale of two eponyms

From Broca's area to Broca's aphasia: a tale of two eponyms. Featuring @adeenflinker's work!

The definitive version of this post was originally published on May 27, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

In 1861, the French scientific journal Bulletin de la Societe Anatomique published an article that would prove immeasurably important to the study of language and of the human brain [1]. The article described M. Leborgne, a middle-aged patient who…

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#Broca&039;s aphasia #Broca&039;s area #electrocorticography #historical neuroscience #intracranial EEG #language #MRI #speech

Book review: Tales from both sides of the brain, by Michael Gazzaniga

I’m introducing a new category of posts: short reviews of neuro-related books I recently read and liked (or didn’t!). I am starting this series with Michael Gazzaniga’s scientific autobiography, which was published earlier this year.

Michael S. Gazzaniga. Tales from both sides of the brain: a life in neuroscience. Ecco, 2015.

In this very enjoyable book, legendary neuroscientist Michael…

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#autobiography #cognitive neuroscience #corpus callosotomy #Gazzaniga #hemispheric specialization #split brain

Multisensory integration and causal inference in the brain

Multisensory integration and Bayesian causal inference in the brain: new blog post on @PLOSBiology study, w/ interview of the authors!

The definitive version of this post was originally published on April 3, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

Amidst the incessant onslaught of signals that reach our senses every second, how does the brain determine which auditory and visual signals originate from a common source and should be integrated, and which ones should be distinguished as they…

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#audiovisual stimuli #Bayesian causal inference #functional MRI #multisensory integration #spatial localization #ventriloquist illusion

Multimodal measures of brain connectivity: how much should they agree?

The definitive version of this post was originally published on March 3, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

A study recently published in Frontiers in Neurologystarted an interesting discussion on Twitter. The paper, by Stephen Jones and colleagues from the Cleveland Clinic, tackled a seemingly simple question: do measures of cerebral connectivity…

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#brain connectivity #brain stimulation #CCEP #correlation #cortico-cortical evoked potentials #diffusion tensor imaging #direct electrical stimulation #functional MRI #intracranial EEG #multimodal #resting-state

Touchscreen virtuosos: how smartphone use influences the brain maps of our fingertips

The definitive version of this post was originally published on February 4, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

Twenty years ago, very few among us had ever used touchscreens; now, there is one in every pocket. Their ease of use provides a seamless interface with mobile phones, tablets and computers, and we spend literally hours every day interacting with…

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#brain mapping #cortical inhibition #cortical map #EEG #plasticity #smartphone #somatosensory-evoked potentials #touchscreen

How neuroscientists learned to stop worrying and love the bomb

How neuroscientists learned to stop worrying and love the bomb: my latest piece for @PLOSNeuro.

The definitive version of this post was originally published on February 4, 2015 on the PLOS Neuroscience Community website, where I serve as an editor.

Contemporary research in neuroscience is constantly adding to and refining our knowledge of how the brain works. One of the tenets of that knowledge during most of the 20th century—that our brains are supplied from birth with a finite number of…

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#carbon 14 #cold war #dentate gyrus #hippocampus #humans #Jonas Frisen #Karolinska Institute #mammals #neurogenesis #nuclear testing #olfactory bulb #plasticity #radioactive markers #striatum

Brain games not quite ready for prime time

Brain games not quite ready for prime time: my recent post on a PLOS Medicine meta-analysis of computerized cognitive training

The definitive version of this post was originally published on December 23, 2014 on the PLOS Neuroscience Community website, where I serve as an editor.

Ever since video games have become widely available, they have reflected a strong generational divide: most of today’s grandparents probably never played video games, whereas most of their grandchildren play them on a daily basis. Now, after…

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#Computerized cognitive training #meta-analysis #systematic review #working memory

#AESmtg14 highlights: Frontal lobe epilepsy: semiology and cognitive aspects

#AESmtg14 highlights: Frontal lobe epilepsy semiology & cognitive aspects, masterful lesson by Pr. Patrick Chauvel

Here is my live-tweeting from this Special Interest Group session from the 2014 Annual Meeting of the American Epilepsy Society on Dec. 7 in Seattle, WA, collected on Storify.

This session in fact turned into one long presentation by Prof. Patrick Chauvel, from the CHU of Marseille. And it was a truly masterful lesson, with many fascinating video-intracranial EEG presentations of patients with…

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#anatomical-electrical-clinical correlation #anterior cingulate cortex #Chauvel #cingulate gyrus #epilepsy #intracranial EEG #prefrontal lobe #semiology

#AESmtg14 highlights: What parts of the brain are active during seizures?

Here is my live-tweeting from this Investigators’ Workshop from the 2014 Annual Meeting of the American Epilepsy Society on Dec. 7 in Seattle, WA, collected in Storify.

Very interesting, thought-provoking session focusing in part on high-density micro-electrode array recordings of seizures in human patients (“Utah array”). The speakers were:

Dr. Andrew Trevelyan, from Newcastle University

Dr. Hal…

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#consciousness #epilepsy #high-frequency oscillation #high-gamma power #hypersynchronization #micro-electrode array #phase-power coupling #seizure core #seizure onset zone #seizure penumbra

#AESmtg14 highlights: do focal seizure networks matter?

Here is my live-tweeting from this Investigators’ Workshop from the 2014 Annual Meeting of the American Epilepsy Society on Dec. 7 in Seattle, WA, collected in Storify.

This was a great session with many provocative ideas (starting with the title!), chaired by Dr. Jean Gotmanfrom the Montreal Neurological Institute. The general discussion at the end of the presentations yielded several…

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#connectivity #EEG-fMRI #epilepsy #epileptogenesis #functional MRI #intracranial EEG #large-scale neural network

#AESmtg14 highlights: ictal semiology helps to localize the seizure onset zone

Here is my live-tweeting from this Special Interest Group session from the 2014 Annual Meeting of the American Epilepsy Society on Dec. 6 in Seattle, WA, collected in Storify.

These sessions, where very experimented clinicians and neurophysiologists discuss the relationships between the clinical features of seizures (semiology) and the brain areas involved in the seizure revealed by intracranial…

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#epilepsy #intracranial EEG #seizure onset zone #semiology

#AESmtg14 highlights: dense array EEG and source localization in clinical practice

Here is my live-tweeting from this Special Interest Group session from the 2014 Annual Meeting of the American Epilepsy Society on Dec. 5 in Seattle, WA, collected in Storify.

EEG source imaging is a particular forte of the group where I did my PhD, Christoph Michel’s Functional Brain Mapping Laboratory, at the University of Geneva Medical Faculty and Geneva University Hospitals, and of Margitta…

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#Cartool #EEG #EEG source imaging #epilepsy #epilepsy surgery #high density EEG #interictal epileptic spikes #intracranial EEG #irritative zone #MEG #seizure onset zone

#AESmtg14 highlights: Epilepsy as a spectrum disorder (or, another conference already?!)

I have been extremely lucky this year to be able to attend both the Society for Neuroscience’s (#SfN14) and the American Epilepsy Society’s (#AESmtg14) annual meetings in close succession. And as I did for the SFN, I will be live-tweeting and blogging about the AES meeting over the next few days.

To get started, here is a Storify collectionof my live-tweeting of the opening lecture, the Judith…

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#epilepsy #Frances Jensen #live-tweeting #spectrum #Storify

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