a new apple we know the devil ost
$LAYYYTER

Product Placement

blake kathryn

@theartofmadeline

oozey mess
🪼

pixel skylines
Three Goblin Art
tumblr dot com
Misplaced Lens Cap
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2025 on Tumblr: Trends That Defined the Year
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I'd rather be in outer space 🛸

Andulka
KIROKAZE
"I'm Dorothy Gale from Kansas"

Janaina Medeiros
NASA
AnasAbdin
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@xboy-herox
a new apple we know the devil ost
What matters in life is tagging posts as your ocs
I'm allowed to be a little parasocial because I am famously normal
arvid is on another level because what do you mean he managed 68 lap old tyres in Monaco and was the second to last driver to pit today but still came out in the points 🥹 that's my tyre whisperer fr
when you're arvid lindblad and you got a 9 on your maths and chem gcses a year early and you're a former snapchat wyll warrior and you correctly prophesized to lando norris you'd see him in f1 in 5 years and you aura farm every other day and you're nonchalant asf and you're a model by nature and you're on a magazine cover and you're a skateboarder and you're really into fashion and you don't follow the rich millionaire herd that plays golf and lives in monaco and you somehow do this while making your way into the f1 record books and oh you're also like the coolest guy on the grid ok ok we get it
via explore-blog:
The very first photo of the moon, taken by John William Draper in 1839.
Draper immigrated to the United States from England and became a chemistry professor at NYU. This daguerreotype print was the first of a series of silver platinum plates he shot using a telescope. Draper was also the first person to shoot a portrait in America, a photograph of his sister Dorothy-Catherine . In 1864, he became chairman of the American Photographic Association.
Pair with Ordering the Heavens, a visual history of humanity’s quest to depict the cosmos before telescopes.
Curious how it was done before we had fancy space telescopes? I recommend this slideshow from National Geographic: Milestones in Space Photography, featuring the first shot of the sun, taken by Louis Fizeau and Leon Foucault in 1845:
Hemoglobin: Binding O2 — Cooperation Makes It Easier
I’m pretty sure I’m the only one in my biochemistry class that is so excited about how incredible the binding of oxygen to hemoglobin is that I’m losing sleep over it. Anyway, the gorgeous and colourful animination above, from the Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), illustrates the conformational change upon oxygen binding to hemoglobin.
What is hemoglobin? Hemoglobin is a remarkable metalloprotein (a protein that contains a metal ion), found in red blood cells, that plays an important role in oxygen transport. Hemoglobin is a heterotetramer consisting of 2 α subunits (light pink and the other one can’t be seen) and 2 β subunits (light purple and light blue), arranged in 2 αβ subunits (2 sets of dimers). Each subunit contains one heme group (red) — a protoporphyrin ring with Fe2+ in the ring centre — resulting in four heme groups in total.2
How does hemoglobin bind O2? Interestingly, hemoglobin binds O2 (teal) cooperatively: when one heme group binds to O2, it increases the other heme groups’ affinity (ability to bind) for O2. This is a type of allosteric interaction — the change in shape of a protein that results from binding of a molecule at the allosteric site (a site other than the active site).2
Why does this happen? When O2 is not bound (deoxy), Fe2+ lies a little outside of the protoporphyrin ring. When O2 is bound (oxy), Fe2+ ”pops” into the ring, pulling with it a histidine (yellow), His, residue. Also attached to His is an α-helix (orange), which also shifts. All of this movement disrupts and forms new interactions between the α1β1-α2β2 interface.3 It is this conformational change that increases the other hemes’ ability to bind to O2. Noticeably, as more O2 binds to hemoglobin, the α1β1 dimer will rotate 15° relative to the α2β2 dimer, which can be observed in the animation.2
Animations and movies illustrating conformational changes upon oxygen binding to hemoglobin (Janet Iwasa)
YouTube video about hemoglobin-oxygen dynamics (ThePenguinProf)
Ribbon structure of hemoglobin (The Full Wiki)
Sources used: 1. Hemoglobin animation: RCSB PDB 2. Krisinger, M. BIOC 202 Lecture on Protein Function. Presented at the University of British Columbia. May 27, 2013. 3. RCSB PDB. Hemoglobin. http://www.pdb.org/pdb/101/motm.do?momID=41 (accessed May 27, 2013)
I’m glad I’m not the only one that thinks this is magnificent.
Iori Tomita - New World Transparent Specimens (2005-)
Fisherman-turned-artist in Yokohama City, Japan, Tomita creates art using the skeletons of various dead marine specimens, which he preserves and then colors with bright shades of dye.
The process strips down each creature to the toughest parts of its remains and Tomita has dyed more than 5,000 dead creatures since 2005, which is amazing, considering each piece takes at least a few weeks to complete, and some up to a year.
“Although these are just transparent specimens, they’re filled with the drama of organisms which I have so much love for. I want people to enjoy the beauty of life, treat life with respect and understand that there is drama happening that is not centered on themselves when they look at the specimens. These specimens which you see here are actually animals that have died for some some reason or whose carcasses were discarded from pet shops or fishermen. I use those animals which passed away and repurpose them.”
Happy spring, nature lovers!
Actinobacteria (actinomycetes), Geosmin, and Petrichor. (Don’t roll your eyes. Look them up!)
Tracheal Repair Surgery
everything?
what’s the funniest show that could be pitched to someone tumblr style like “omg watch this there is a gay character and autistic representation!”
(wanting to make a post about something but it reveals too much about your personal life) i have had a negative experience
Pokémon Black and White (2010)
The older i get the more i understand why some people become obsessed with privacy, not because they’re hiding something, but because being constantly perceived starts to feel spiritually exhausting.