leaf

[zybilna]

One thing that makes me kinda sad is seeing people who feel like TTRPGs just aren't for them because they bounced off of some element that is clearly just a symptom of them trying out D&D5e. Like people who have had a hard time with learning the rules would probably do well with any system where the rule formatting and play culture around learning them aren't a mess. One friend of mine didn't like waiting a long time for turns to come up in combat, not even knowing that many games don't even use a turn-based structure.

A lot of D&D5e defenders on here like to claim that asking someone to learn a new system is "gatekeeping" somehow, but I'd argue that acting like one game is emblematic of the entire medium to the exclusion of people who don't click with that one game is way more meaningfully a form of gatekeeping, even if it's fully unintentional.

I strongly believe that not all RPGs are gonna appeal to everyone, but there is an RPG out there for everyone, and I just hope that people who haven't clicked with the most common option to be introduced to can find something that works for them.

[charlesoberonn]

Turns out you can roll a 7 on a d6

but only once.

[beemovieerotica]

the cognitive dissonance from people who want the products of modern medicine but get weird about animal research. like im sorry but this is necessary for the survival of the society we currently live in. and the scientists who work on these things are not evil cackling psychopaths. anyone you talk to in animal research has incredibly complex feelings about their work and incredibly complex relationships to the animals in their care. there are regulations and oversight and penalties in place to make the work as humane as possible and scientists are overwhelmingly the ones enforcing and advocating for better care.

[beemovieerotica]

@velvetdemon I'm doing a full reply because I want to give this question the time and space it deserves, and I really do appreciate your curiosity about this.

The short answer: It is deeply unethical. There are nowhere near enough willing patients in the world to be able to do this, and it would be criminal to put them through this.

The long answer: The one side of the equation you're focusing on is: how much of a drug is too much, to the point where it will cause negative side effects or even death? And this is crucial to know. But it's not just a matter of finding out the lethal dosage of a heart cholesterol medication, you need to know that it can actually lower the cholesterol of any living thing. There is no way to know this without giving it first to...a living thing.

But beyond this, I need to emphasize: The goal of a drug trial is to effectively cure people who are already suffering from disease, who are living on limited time.

Drug trials don't just happen on any member of the public, they need to happen specifically on people affected by the disease you're trying to treat. There is at any time a very limited and very marginalized population of the world affected by early onset, familial Parkinson's disease. Because you cannot ethically induce disease in a human being, you are working with, speaking with, and helping patients and their families who are hopeful and desperate for a cure.

If you were to jump straight to human trials from petri dishes, not knowing absolutely anything about how the drug functions in a living, breathing animal body, it would look like this:

We didn't know that minute quantities of the drug interact lethally with x, y, z medication that people are commonly also taking. X number of patients have died as a result.

We didn't know that the drug is fatal to people with [common variant] in their genetics. X more patients have died.

We didn't know the drug exacerbates x, y, z chronic illnesses. X number of people have acquired permanent, lifelong disabilities.

We didn't know the best way to deliver the drug, so we tried multiple ways: the people who received it intravenously are now suffering from a painful, costly, and debilitating condition that did not happen with the ingested form.

I could go on, and on, and on.

The vast majority of these problems can be nearly or almost entirely averted by testing other animals first.

These are all people who possibly could have waited for the normal progression from animal testing to human testing and thus received better outcomes. Some people will pass away in the time it takes to get to that point, and that's heartbreaking, and we all wish science could be faster.

But the cost of expediting science could mean a life of profoundly greater suffering or an even shorter life than the one where no intervention happens at all. And at that point, you have completely exhausted your trust, your goodwill, and your patients' hope, after you've failed to do anything or even worsened the lives of people who are already deeply suffering.

[manslaughter]

hi, i’m an animal research professional. making sure laboratory animals stay alive, healthy, and enriched has been my full-time job for several years now.

animal research is not the mad scientist wild west that PETA wants you to think it is. there are extremely strict federal laws in place to protect the well being of these animals. animal welfare organizations like AAALAC ensure that lab animals are treated with dignity & respect and are given enough specialized care & enrichment to be happy and content in captivity, just like AZA accreditation with zoos.

not a single animal from a zebrafish to a mouse to a dog to a macaque goes unaccounted for. if an animal gets moved to a new cage, paired for breeding, has a procedure performed on it, gives birth, gets sick or injured, dies, etc. it is legally required that this information is recorded and kept on file for the US federal government to access. failing to record & retain this information is very much punishable by US federal law.

let me tell you - if you abuse or kill an animal, even a mouse - you are almost certainly getting both fired & blacklisted from the industry. if you abuse or kill a more ‘advanced’ animal, such as a dog or monkey, you will likely face criminal charges. killing a monkey is as serious and disastrous as a nuclear meltdown. you are expected to reasonably explain every illness, injury, or death of an animal under your care. you must record all of this information. animals that are clearly suffering with low QOL are required to be euthanized according to AVMA guidelines.

research animals are highly expensive. yes, even the "lesser" animals like mice. the cheapest mice will run you a few hundred $ per individual, with some of the most expensive mice i've cared for being $25,000 per individual. in research we have the "three Rs" - reduction (reduce amount of necessary animals to a minimum), refinement (refine processes to ensure research is accurate and animals feel no pain or distress), and replacement (replace animals with non-living research models as they become available). i can assure you no proper research team is wasting animals (*do not* say "b-b-but elon musk--" his research team is actively being investigated for animal abuse by the government).

research methods that do not require live animals are currently being looked into & efforts spearheaded by - you guessed it - the animal research industry itself (notice how the animal rights people are strangely silent & unhelpful when it comes to this?) but current technology is rudimentary and does not compare to live animal models.

some research animal fun facts (US edition):

all species of animals are only allowed to have one single major surgery performed on them in their entire lifetime.

institutions with nonhuman primates must have a behavior program in place (run by knowledgeable primate specialists) to ensure that they are happy and receiving enough daily enrichment and social interaction.

institutions with dogs are required to have physical exercise programs in place. this means every individual dog gets a substantial amount of leashed AND free-roaming exercise daily, including playgroups with other dogs.

a majority of nonhuman primates get to retire to sanctuaries like peaceable primate sanctuary, and almost all dogs get retired and adopted out by organizations like homes for animal heroes. some institutions will also adopt out unneeded young rabbits, guinea pigs, rats, etc.

some strains of mice glow neon green (or orange or blue) under UV light. this is not harmful to them and is commonly seen in cancer research.

so yes, you can rest knowing that laboratory animals are treated with the utmost respect by their caretakers. and you can stop this awful, ignorant talk of human experimentation that will only end in the abuse of nonwhite people, LGBT people, disabled people, indigenous people, and so many others. please just take a look at this wikipedia page if you think “ethical” human experimentation can exist.

[teaboot]

I think that if you had enough daughters AND played your cards right you could spring Mambo Number Five out at the EXACT right gathering and shatter your entire family's trust forever

[teaboot]

The secret is to name them out of order with the lyrics so by the time anyone catches on it's too late

[teaboot]

For me personally the ideal gathering would be my funeral

[teaboot]

A little bit for Monica, she's my wife

A little bit for Erica, for her strife

My books all go to Rita, cause she reads

My greenhouse goes to Tina, she plants trees

The furniture is Sandra's, on my lawn

Jewelry for Mary, she can pawn

Ashes go to Jessica, that's my plan

A little bit of me inside a can (ah!)

[pangur-and-grim]

always doing something annoying

[pangur-and-grim]

can I be honest? I was so pissed off by friends and family criticizing my soap choice that, for half a year, I did an experiment where I washed one hand with Palmolive and one with handsoap, to prove that it didn't make your skin any rougher. and do you know what the result is? it does make your skin rougher. and now I'm even more pissed off.

[heavilyglacialvalhalla]

I love this. This is the beauty of the honest scientific process. You had an idea, you tested it and you still reported the results even though the results disproved your idea.

It's ok to be mad at it, you're an honest scientist.

[sexhaver]

i think about this a lot

[beaft]

i am not a psychiatrist but i do find it really weird how autism checklists are so often focused on "outward" signs of autism rather than what is going on internally. i don't know how to explain it but "do you make eye contact with other people" feels like a much less relevant question than "how does it feel when you have to make eye contact with other people?"

[beaft]

while i'm here, the other one that always pisses me off is "do you interpret idioms literally, for example 'bull in a china shop'?"

well, no, obviously. i know what "bull in a china shop" means because that is a popular phrase with a clearly defined meaning. and if i hadn't heard it before, then i would still not interpret it literally, because it has the cadence of an idiom and i would probably be able to work out from context what it meant. what is the point of this question

[beaft]

third and final complaint: "are you good at noticing subtext?"

i feel like the problem with this question is best illustrated by a conversation i had with a friend a while back, where i said something like, "i feel very safe with you because you don't do subtle hints and you are always very straight-up with me about what you are thinking and feeling."

and he laid a hand on my shoulder and was like, look dude i'm gonna be straight up here. i am subtle with you constantly and you simply do not notice <3

[beaft]

@luckyybones hope you don't mind me screenshotting but you are actually so correct

[minmos]

this reddit post isgoing to make me cry literally let's bask in the sun

[wastrelwoods]

been sort of obsessively combing through articles and websites and resources about top surgery and recovery more and more as I gear up to My Big Day and while I hate to report I may have gotten through most of the scientifically rigorous and reputable sites I am at least, now, stumbling over some of the funnier AI generated slop images i've ever seen in my quest for Patient Information

[brawltogethernow]

They missed. 😔

[zyzscribbles]

Important question

[awkwardbirdsdreaming]

Okay but I think these two are onto something

[verbrannt74]

Test subject

(no bird was harmed)

[orcboxer]

and the post begins

because otherwise it gets kind of visually confusing to parse, which is annoying to some folks, including me

GRANTED not everybody uses the same theme or even the same update. you might have noticed my version of tumblr is earlier than yours (I don't like the new button setup)

but still, it's just about being polite

so now you know

[what-even-is-thiss]

I get people who are like “why do you play Bethesda games” and it’s like what other game studio lets me pick up basically everything in my environment and throw it at people

[notaplaceofhonour]

Ryan Gosling’s career has just been one long quest to climb the Warner Bros water tower

[notaplaceofhonour]

that man has been trying to climb this tower since he was 16. he has asked multiple times, and every time they said no, but now he’s famous enough & variety was able to convince them to do a shoot on the tower. it all led here. it was all for this.

[notaplaceofhonour]

I’m obsessed with the implication that this was a coming-of-age ritual where a boy becomes a man, like a bar mitzvah

[smsomah]

Cormorant fishing in Yangshuo near Guilin, Guangxi, China. Christian Vaisse

Cormorant fishing is an old tradition in which fishermen use trained cormorants to catch fish.

[boringkate]

You listen to music regularly? Why? Have you even tried quitting? Could you quit? You get music stuck in your head? Wow. You're so ruined and music brained. I bet you make your partners listen to music with you when you have sex. Music addiction has really ruined a whole generation. You know it's not realistic to expect reverb in real life, right? You're probably so desensitized that you don't even feel anything anymore when you hear a bird singing that it wants some fuck.

[paradigm-adrift]

I don't have a problem with people listening to music per se, but I do have a problem with the music industry exploiting & mistreating artists.

Personally, I abstain from all music in order to keep my hands clean but really music should just be illegal outright to protect musicians from abuse.

[terramythos]

holy shit this person in the notes

[derinthescarletpescatarian]

Anyone got that comic about making up a strawman to make a point and then turning around and the strawman is standing there

[benbrusque]

This one?

[derinthescarletpescatarian]

Thanks

[william-s-churros]

i think i saw a movie like this once

[maidslime]

Ok I needed to know the story and

Guy makes a really stupid decision and gets in a car accident -> no real damage from accident but insurance goes up -> starts beating himself up over his stupid decision -> gets depressed -> starts to realize he's single and had crash been worse he'd die alone -> realizes he's never had a relationship or even a crush and starts wondering what he'd want out of a relationship -> starts to realize he doesn't really like girls so he thinks he must be gay -> realizes he likes girls and boys about the same amount, so he must be bi -> later realizes that "same amount" is none at all -> he's ace

[birdwarde]

I present to you, the second bird in our Bird Bags lineup, The Pigeon!

Preorders will be available this Saturday for National Pigeon Day!