Elves... and Jiang Cheng @chibiwing-aka-nozomikei - Tumblr Blog

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I don’t say this often, but you really should unmute and listen to the song

My favorite part of this monstrosity is the auto-generated question at the bottom. What size items fit inside? Babe what size items do you have?

Also "versatile for gym". Imagine rocking up to your gym and dropping this next to your locker. Unhinged.

man1cpixiedreampuppy

magneto: how do you have so much faith in humans to do the right thing when they have proven you wrong time and time again?

the humble charles xavier:

picaroroboto

the way Ishikawa's FFXIV writing is like "Being a hero is bloody work and its naive to pretend it isn't, holding on to hope against a cynical world is unendurably painful, and your attempts to create lasting change will often be spit on by the very people you're trying to save, but in the end no kindness however small is ever wasted or forgotten." and the way I'm like "okay lemme go cry for a minute" in response

rowein1102

My contribution to the legendary MXTX calendar, 2027 edition!

I hope you like it! If you’d like a copy, you can check the Kickstarter link here:

https://www.kickstarter.com/projects/deepbreath/mxtx-fan-calendar-2027?ref=project_build

The participants in this edition are very talented, and it turned out beautifully 🥺👌

It’s always an honor to be part of this project 😌🫶

catasters

idratherhavefreedom

$felinefractious blog's avatar$

felinefractious

[Image Source]

Clinical, Histopathological and Genetic Features of a Cutaneous Adnexal Polycystic Syndrome in Lykoi Cats: A Prospective Study of 10 Cases

Objectives

The Lykoi is a recently recognised feline breed with a unique coat phenotype caused by six variants of the Hairless (HR) gene. A specific severe cutaneous comedonal syndrome has been reported in this breed. The aim of the study was to carry out a clinical, histopathological and genetic characterisation of this syndrome.

Methods

Prospective data collection included clinical evaluation, skin biopsies for histopathology, trichoscopic examination of hair shafts, blood sampling for haematology and biochemistry, cutaneous swabs for bacteriological culture, and buccal swabs for DNA extraction and genotyping.

Results

In total, 11 privately owned Lykoi cats were enrolled, including those with varying degrees of skin involvement and one healthy cat. Cats were aged 1.5–7 years at the time of diagnosis. Clinical presentation was characterised by papular lesions and comedones, ranging from severe generalised forms (n = 6/10) to moderate regional forms (n = 2/10) and to mild scattered forms (n = 2/10). Histopathological lesions from skin biopsies revealed infundibular follicular cysts (n = 9/10), sebaceous gland (duct) cysts (n = 10/10) and sweat gland cysts (n = 5/10). Genetic analysis identified 5/6 described HR variants among the 10 affected Lykoi and the control Lykoi.

Conclusions and Relevance

This cutaneous syndrome shows a variable clinical severity that is not fully explained by genotype alone. The consistent presence of cysts from all three adnexal structures, even in clinically unaffected skin, supports the recognition of a novel skin condition, which we propose to name cutaneous adnexal polycystic syndrome (CAPS) in Lykoi cats. Further research is needed to elucidate its pathogenesis.

>>[Read Full Study]<<

I strongly encourage you to read the full study, it’s extremely interesting - although be warned, it does have visuals.

I’ve talked about the Lykoi breed before and I’m glad they’re finally getting more attention, I hope further research is done into CAPS.

Something I thought was interesting was how the asymptomatic Lykoi had an isolated sebaceous duct cyst, she is 3y at the time the sample was collected and the most common age of symptom onset appears to be 3.5y - 4y.

Will she still be subclinical a year from the study?

dni-archive

abysslll

itsladykit

Motion Picture Association of America.

waywardworldhopper

Entertainment Software Rating Board

dragonflavoredcake

Rejection sensitivity dysphoria is the weirdest ADHD symptom ever. Like hello yes my weird brain chemistry manifests as Whiny Crybaby Disorder

eroscestlavie

btw this is not a universally agreed upon "symptom" of ADHD and I think many people would benefit from treating it as part & parcel of ADHD's broad, foundational trait: inability to do emotional regulation. A feeling of total rejection and terror at failure is a treatable and manageable issue. For me, I found it easier to manage once recognized that the reason I was having these reactions is that like many other emotional states, I couldn't "exit" an emotional state related to feelings of rejection once I was in it.

imo way too many people are going through life thinking they're just going to be sensitive to rejection for life because of how some people (not OP, but definitely plenty of ADHD influencers) talk about this "symptom." I don't think it's terribly productive that it gets constantly cordoned off as its own thing. like a lot of ADHD, while it sucks to have it shape your life up to the point you realize what it is, it is indeed possible to exposure therapy & DBT your way out of it.

signed: someone with ADHD who used to not be able to take critical feedback from anyone every and is now a freelancer and gets critical feedback three times before breakfast. still workin on it but it's very possible to go from "whiny crybaby disorder" to "mostly functional, if slightly sensitive ADHD adult"

grison-in-space

I also think it's worth noting that rejection sensitive dysphoria is most parsimoniously interpreted as a trauma reaction—a learned response to a potential signals of social relationship deteriorating for reasons the ADHD person can't necessarily control. Social relationships are incredibly important to humans, and ADHD (especially undiagnosed and undisclosed) really sets us up to fail. This is especially true given that perceived social blame for stressful situations is a massive factor in transmuting stressful experiences into lasting trauma, and ADHDers are typically judged to be personally responsible for the failures that happen as a result of attentional, time awareness, or memory failures.

What conceptualizing RSD as a category of trauma response to social triggers does is allow us to treat it like any other trauma response. It pulls RSD out of the bioessentialist framework and into the realm of injuries that can be treated, learned associations that can be unlearned. It turns out that the same techniques that help with PTSD triggers, including the same damn meds (hi, clonidine), are effective for helping reduce RSD. (It also explains why RSD is also common in autistic people, who often have a similar history of social error and narratives of self blame, without requiring inherent neurological differences.)

It's a common kind of stress injury, basically. It's not Whiny Crybaby Disorder; it's more like shin splints. Getting better shoes for running, being careful about the ground you run on, and letting the splints heal properly can all help make shin splints go away when you've been running barefoot on concrete roads your whole life.

piernik-miodowy

“Boogie Street ‘52, Revachol” (Kim has this in his wallet)

A revamp of my 2022 Disco piece hehe

transguyarchive

the Trans Guy Archive's complete guide to Transmasculine HRT

After a couple months of research and personal testimony, we are very pleased to finally publish this extremely extensive guide on testosterone hormone replacement therapy!

The process of getting and taking testosterone is often daunting. The outside hateful rhetoric from bigots doesn't help either. This guide is aimed for anyone interested in hormone replacement therapy, from newcomers to those already on their HRT journey.

The all-in-one guide to testosterone hormone replacement therapy for trans guys!

Huge thanks to everyone online and in-person who helped contribute to the guide!

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snailkites

Crested Caracara being allopreened by two Black Vultures! This is such an interesting behavior and one that's typically one-way (preening by vultures to caracara). Here you can see the caracara either attempting to reciprocate but getting rebuffed by both vultures, or telling them to stop for now.

[Video source]

peekychu

They should invent a cry for help that has zero negative effects on anybody and also that makes everyone treat you like a little animal in a cardboard box. But everyone’s cool with it because you’re a cute little animal and not an adult human that needs to get their shit together to stay alive

blackshvck

the idea that every summer will be as hot if not hotter than this for the rest of my life is unbearable i need to (remembers suicide jokes are bad for my mental health) murder an oil executive