#lupron

[macgyvermedical]

heyy, in your trans day of visability post you mentioned lupron. what is it and what would one use it for?

Lupron (leuprolide) is a drug that blocks the production of sex hormones (estrogen and testosterone). It is used for a lot of conditions, such as prostate cancer, uterine fibroids, and endometriosis.

It is also used off label to suppress puberty in transgender youth, and sometimes to suppress testosterone production in adult transgender women.

Where it really shines is as a puberty blocker. If a child is experiencing gender dysphoria as a result of puberty, leuprolide can prevent that puberty from progressing. This means no more breast development in those assigned female at birth, and no more facial/body hair growth and voice change in those assigned male at birth. This decreases the need for gender affirming surgery later (don't need FTM top surgery if you never grow boobs).

The nice thing is that leuprolide is completely reversible- if the child decides later that they don't want to transition, they just stop the leuprolide and their puberty picks up where it left off.

If they reach the age where they can start cross-gender hormone therapy and still want to transition, they can seamlessly transition to cross-gender hormones and proceed through their chosen puberty.

[cakesexuality]

I'm still riding the high of my gynecologist agreeing to a hysterectomy this past Tuesday!!

Reminder that I take questions about my journey with this!!

My name is Billie and I'm an enby/androgyne who may have endometriosis and/or adenomyosis and I am having a hysterectomy in 15 months from now!! I am also going back on Lupron Depot soon after previously being on it from late 2022 to early 2024, was on Depo-Provera from late 2019 to late 2022, have been on Alysena 21 since late 2023, and had a laparoscopy in 2023

I've been sick since late 2018 and I feel like I may have gender dysphoria over my periods so I'm excited for this and plan on throwing myself a hysterectomy party and getting a cake and everything!! (Obviously I'm getting a cake, I'm Tumblr user cakesexuality)

I love talking about my health on Tumblr and have tags for it!! #the estrogen is slapping right now is for my reproductive health specifically and #doctor bitchcraft is for physical health in general (embedded the links in this post but also tagged below), but if you can't find something in the tags or if it's too deep in the tags for you to feel like looking for it, you can slam that link above that I put in larger text to ask me a question!!

[p0pipos]

sad that this young woman has had her health damaged so severely by puberty blockers, but is so scared of being excommunicated by her ingroup for even considering what terfs are saying that she feels the need to spit such disgusting performative bile at other women. when the evil radfems have been the ones warning about these dangerous hormones all along.

[kittyit]

'Miracle drug' called junk science

'Miracle drug' called junk science

May 21, 2009

[detransition]

"For years, Sharissa Derricott, 30, had no idea why her body seemed to be failing. At 21, a surgeon replaced her deteriorated jaw joint. She’s been diagnosed with degenerative disc disease and fibromyalgia, a chronic pain condition. Her teeth are shedding enamel and cracking.

None of it made sense to her until she discovered a community of women online who describe similar symptoms and have one thing in common: all had taken a drug called Lupron.

Thousands of parents chose to inject their daughters with the drug, which was approved to shut down puberty in young girls but also is commonly used off-label to help short kids grow taller.

The drug’s pediatric version comes with few warnings about long-term side effects. It is also used in adults to fight prostate cancer or relieve uterine pain and the Food and Drug Administration has warnings on the drug’s adult labels about a variety of side effects.

More than 10,000 adverse event reports filed with the FDA reflect the experiences of women who’ve taken Lupron. The reports describe everything from brittle bones to faulty joints.

In interviews and in online forums, women who took the drug as young girls or initiated a daughter’s treatment described harsh side effects that have been well-documented in adults.

Women who used Lupron a decade or more ago to delay puberty or grow taller described the short-term side effects listed on the pediatric label: pain at the injection site, mood swings and headaches. Yet they also described conditions that usually affect people much later in life. A 20-year-old from South Carolina was diagnosed with osteopenia, a thinning of the bones, while a 25 year-old from Pennsylvania has osteoporosis and a cracked spine. A 26 year-old in Massachusetts needed a total hip replacement. A 25-year-old in Wisconsin, like Derricott, has chronic pain and degenerative disc disease.

“It just feels like I’m being punished for basically being experimented on when I was a child,” said Derricott, of Lawton, Okla. “I’d hate for a child to be put on Lupron, get to my age and go through the things I have been through.”

Women fear drug they used to halt puberty led to health problems (PBS) graphic from woman-for-women | thinking of detransition? you are not alone

[ghostlybassoon]

[religion-is-a-mental-illness]

Short-term outcomes of pubertal suppression in a selected cohort of 12 to 15 year old young people with persistent gender dysphoria in the U

Background In adolescents with severe and persistent gender dysphoria (GD), gonadotropin releasing hormone analogues (GnRHa) are used from e

Psychological Outcomes of 12-15-Year-Olds with Gender Dysphoria Receiving Pubertal Suppression in the UK: Assessing Reliable and Clinically

The evidence base for psychological benefits of GnRHA for adolescents with gender dysphoria (GD) was deemed "low quality" by the UK National

Abstract

The evidence base for psychological benefits of GnRHA for adolescents with gender dysphoria (GD) was deemed “low quality” by the UK National Institute of Health and Care Excellence. Limitations identified include inattention to clinical importance of findings. This secondary analysis of UK clinical study data uses Reliable and Clinically Significant Change approaches to address this gap. The original uncontrolled study collected data within a specialist GD service. Participants were 44 12–15-year-olds with GD. Puberty was suppressed using “triptorelin”; participants were followed-up for 36 months. Secondary analysis used data from parent-report Child Behavior Checklists and Youth Self-Report forms. Reliable change results: 15–34% of participants reliably deteriorated depending on the subscale, time point and parent versus child report. Clinically significant change results: 27–58% were in the borderline (subclinical) or clinical range at baseline (depending on subscale and parent or child report). Rates of clinically significant change ranged from 0 to 35%, decreasing over time toward zero on both self-report and parent-report. The approach offers an established complementary method to analyze individual level change and to examine who might benefit or otherwise from treatment in a field where research designs have been challenged by lack of control groups and low sample sizes.

==

Indeed.

[d3nt4l-d4m4g3]

if you would like some concrete evidence of the negative side effects of lupron, also known as puberty blockers, look no further than the WebMD reviews for it! This drug has been used for everything from endometriosis to prostate cancer to precocious puberty and it does almost nothing its prescribers promise. What is promised almost certainly is lifelong debilitating pain!!

Find 171 user ratings and reviews for Lupron Depot Intramuscular on WebMD including side effects and drug interactions, medication effective

Some highlights:

Now check the reviews from Drugs.com:

Reminder that they’re giving this stuff to potentially hundreds of children in America! At this moment!! There are over 300 youth gender clinics in the US who wanna give THIS to children!!!

Yes—before you accuse me of cherry-picking there ARE positive reviews of Lupron on these sites— keep in mind many of these people are choosing between dying prematurely (in the case of end stage prostate cancer) or suffering from uterine pain and hemorrhaging (in the case of endometriosis) and Lupron. Meanwhile, this drug is now being given to healthy children who need never make such a decision because they are not between a rock and a hard place like terminal/chronically ill victims are. They are ONLY being abused, with no potential medical benefits.