These tactics worked so well for so long because until quite recently lefties got short shrift and had it trained (if they were lucky) or beaten out of them.
Use of sword and shield is a classic demonstration of how right-handedness predominated. There’s historical mention of left-handed swordsmen (gladiators and Vikings), and what a problem they were for their opponents, but that only applies to single combat.
A left-handed hoplite or housecarl simply couldn’t fight as part of a phalanx or shield wall, since the shields were a mutual defence (the right side of the shield covered its owner’s left side, its left side covered the right side of his neighbour to the left, and so on down the line) and wearing one on the wrong arm threw the whole tactic out of whack.
Jousting, whether with or without an Italian-style tilt barrier, was run shield-side to shield-side with the lance at a slant (except for the Scharfrennen, a highly specialised style that’s AFAIK unique.) Consequently left-handed knights were physically unable to joust.
There’s a creditable theory (I first read it in “A Knight and His Horse”, © Ewart Oakeshott 1962, 1998 and many other places since) that a knight’s “destrier” horse - from dexter, “right” - was trained to lead with his right forefoot so that any instinctive swerve would be to the right, away from collision while letting the rider keep his shield between him and harm. (In flying, if a pilot hears “break!” with no other details, the default evasive direction is right.)
The construction of plate armour, whether specialised tournament kit or less elaborate battle gear, is noticeably “right-handed“ - so even if a wealthy knight had his built “left-handed” it would be a waste of time and money; he would still be a square peg in a world of round holes and none of the other kids would play with him.
Even after shields and full armour were no longer an essential part of military equipment, right-hand use was still enforced until quite recently, and to important people as well as ordinary ones - it happened to George VI, father of the present Queen of England. Most swords with complex hilts, such as swept-hilt rapiers and some styles of basket-hilt broadsword, are assymetrical and constructed for right handers. Here’s my schiavona…
It can be held left-handed, but using it with the proper thumb-ring grip, and getting maximum protection from the basket, is right-handed only. (More here.) Some historical examples of left-hand hilts do exist, but they’re rare, and fencing masters had the same “learn to use your right hand” bias as tourney organisers, teachers and almost everyone else. Right-handers were dextrous, but left-handers were sinister, etc., etc.
However, several predominantly left-handed families did turn their handedness into advantage, among them the Kerrs / Carrs, a notorious Reiver family along the England-Scotland Borders, by building their fortress staircases with a spiral the other way to the OP image.
This would seem to be a bad idea, since the attackers (coming upstairs) no longer have their right arms cramped against the centre pillar - however it worked in the Kerrs’ favour because they were used to this mirror-image of reality while nobody else was, and the defender retreating up the spiral had that pillar guarding his right side, while the attacker had to reach out around it…
For the most part Reiver swords weren’t elaborate swept-hilt rapiers but workmanlike basket-hilts. Some from Continental Europe have the handedness of my schiavona with thumb-rings and assymmetrical baskets, but the native “British Baskethilt” is a variant of the Highland claymore* and like it seems completely symmetrical, without even a thumb-ring, which gives equal protection to whichever hand is using it.
*I’m aware there are those who insist “claymore” refers only to two-handers, however the Gaelic term claidheamh-mòr - “big sword” - just refers to size, not to a specific type of sword in the way “schiavona” or “karabela” or even “katana” does.
While the two-hander was the biggest sword in common use it was the claidheamh-mòr; after it dropped out of fashion and the basket-hilt became the biggest sword in common use, that became the claidheamh-mòr.
When Highlanders in the 1745 Rebellion referred to their basket-hilts as claymores, they obviously gave no thought to the confusion they would create for later compilers of catalogues…
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