holy shit
One Nice Bug Per Day
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EXPECTATIONS
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macklin celebrini has autism

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@koreancrows
holy shit
Trace amounts of Monica in my life
A statistically insignificant level of Monica in my life
My life manufactured in a facility that also processes Monica
Too funny to leave in comments @inkskinned
I needed something not-horrible today, and Mr. Onion (if so I may call him) delivered:
(link to post on bsky) Thanks, @theonion. I bet this nets you a bunch of new subscribers, too.
thought of this immediately and was delighted to discover itâs the same op
I feel like I need to share this because idk if Europeans are familiar with the presence of Aldi in the US, but at least especially in my area theyâve been growing a lot recently. Like Aldi bought out some local failing grocery chains where I live (Louisiana) and have opened Aldis in all these somewhat rural communities and small towns, which for the record Iâm fine with
But as a result of this they are advertising a lot more in my area and also in many cases, the people in these areas have never been confronted with Aldi or any European grocery store. So the ads that Aldi is pushing out to its new US customer base feature a cowboy shopping at Aldi who is explaining to new Aldi customers how Aldi works. Like this cowboy is explaining you gotta put a quarter in the shopping cart and why there are very little name brands. A cowboy is how they want to reach their American customer base. They gave us a cowboy
Here he is, the Aldi Cowboy
the life i have definitely never longed for, fuck you for even implying that
with apologies to anna haifisch creator of the original image
"Neighborhood Watch"
as a birdwatcher, i registered a certain familiarity with how the entire neighborhood converged with their horns and whistles to drive away the threat. this is definitely a rough piece, but i had to get it out of me.
high ambient background football levels reminded me to actually finish this Personal Lore That Caused My Books comic
are you guys hearing about this dude working to developing a vaccine for cats that he's hoping would like. theoretically double their lifespans?
turns out i wasn't making that up, his name is Dr. Toru Miyazaki! he also wrote a book called "The Day Cats Live To Be Thirty", so cats are kind of his thing.
apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.
As they age, almost all cats develop kidney disease, from which they eventually die. Just as in humans, kidney disease i
Dr. Toru Miyazakiâs AIM injection for cat kidney disease enters trials in 2025, aiming for a 2027 release. Greycoat Research supports the sc
whoa wait i actually read the articles and it's so much cooler than just that!!
dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!
although his research was focused on cats, it's already being used to develop drugs for humans too!
on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.
furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.
annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D
man just think, not only could our kitties start living longer, healthier lives, but just maybe dialysis will become as rare and obsolete as the iron lung is for people. what a badass Dr. Toru is!
"But I don't want to turn people into dinosaurs. I wanna cure kittie kidneys!"
Update: So they have done clinical trials and have submitted it for approval as of april 2026. They are expecting it to be available late 2026/early 2027
The AIM protein drug for feline chronic kidney disease has been submitted for approval in Japan (April 2026). We break down clinical trial d
As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%
New 2026 study: AIM protein boosts cat kidney disease survival from 20% to 80%. Discover how this scientific breakthrough is changing the fu
Our cat Scout is in the early stages of kidney disease. This might be available in time to save her!
Lunar new year is coming up so I drew this based on the beautiful fat horse sculpture in nanjing
#JOY. HORF BE UPON YE
Googled something about quick hydration and it suggested big jug of water, couple tbsp pickle juice, dash of lime juice.
Its surprisingly tasty????
Pleased to report that after a day of this i am not longer craving caper brine and my mouth is not dry as usual. There's some good suggestions in the notes too that I want to try.
-ancient roman posca: water, red or white wine vinegar, honey, salt, herbs (coriander, mint, thyme)
-switchel: water, ginger, vinegar, sweetener, lemon, salt
-ayran: yogurt, water, salt, mint
-Agua pepino: water, cucumbers, lime, sugar, optional mint.
I have been reminded of:
-shrub: vinegar, sida water, elderberry (or other berry), sugar.
I have now been informed of
-sekanjabin: honey, vinegar, mint, water.
"Wow, I wonder why this post was popular this week."
-sees the reports of the heatwave in Europe-
"... ah."
Follow the money behind America's data center boom. Track 2,300+ projects, PAC spending, and the politicians who sign off on it.
cmon child safety lid you know it's me
WHAT does this tag mean
Richard Nixon once called in staff to help him open an allergy-pill bottle. It was the childproof type of bottle, with instructions saying âPress down while turning.â The cap had teeth marks on it where Nixon had apparently tried to gnaw it open
lmfao what the fuck!
source: richard nixon: a psychobiography
i canât find the reblog chain that mentions it but itâs important to me that people know it was richard nixon himself that had signed the legislation requiring child safety lids on pill bottles
Where's that tweet about how American chants are "let's go [team name] and some other country (Irish?) fans are "I've made up a song about the other team's drinking problem to the tune of London Bridge Is Falling Down one two three"?
i love shipping magazines and i especially love them when they sound like they were written by a mildly aggravated cargo ship
Oh look it's distantly time for one of my favourite poems, Hymn of Breaking Strain (by Kipling, published 1935). Verses 1-3 are the most directly relevant for "industrial engineering and human failure factors" but I have included the rest of the poem for completeness. I like to read it through a mental health lens.
"Now I've shot so many Nazis, Daddy will have to buy me a sable coat." (From his Wikipedia article).
Neil Munro "Bunny" Roger
June 9, 1911-April 27, 1997.
Bunny Roger killed a bunch of Nazis and then invented Capri pants.
He was expelled from Oxford for his indiscrete gayness (discrete gayness being perfectly fine at Oxford and part of the curriculum until...today probably, at least like 1992?). Then, having been sent down to London, he started his own fashion business, and his first client was Vivien Leigh.
Bunny served in WWII, killing fascists in North Africa and Italy, and often wearing a mauve scarf in the field. Roger claimed that he had gone into a battle brandishing a rolled-up copy of VOGUE and commanding: "When in doubt, powder heavily!"
Roger was known in high society for his themed soirées; Diamond, Amethyst, and Flame Balls were held to celebrate his 60th, 70th, and 80th birthdays. He wore a curious plum colored catsuit with a feathered headdress at his 70th birthday ball in 1981. At his 80th, he made his entrance in a catsuit of scarlet sequins with a cape of orange organza, greeting his guests from behind a wall of fire. His parties were covered by the newspapers, including a New Year's Eve Fetish Ball where the proper upper class mixed with young guests in rubber S/M gear.
From an obituary: "Beneath his mauve mannerisms, Bunny was stalwart, frank, dependable and undeceived; to onlookers a passing peacock, to intimates, a life enhancer and exemplary friend."
From another obituary:
He served valiantly in every way.
happy 125th birthday to bunny roger
Found this color photo:
And this in-memoriam piece.
(he did not precisely invent capri pants- Sonja de Lennart did, and they popularized them together)