@caesarsaladinn I had a whole discussion with a history major who was extremely confident that smallpox is a “common childhood illness” with a very low death rate. Therefore, she believed that historical smallpox outbreaks were either massively exaggerated or used as a cover-up for something else (since “smallpox isn’t that bad.”) I eventually asked if she was possibly confusing smallpox with chickenpox, at which point she said, “aren’t they the same thing?”
One of the less deadly variants of smallpox was called cowpox, and the fact that dairy maids who contracted it tended to avoid the worst affects of smallpox is part of the development of vaccination
Cowpox is actually a separate (but very similar!) virus!
There's a lot of confusion about different "poxes" in this post (which wasn't my intention, and now I feel bad), so here's a general overview (also, obligatory apology for messiness, this was written at like 1 AM):
Smallpox:
Smallpox, caused by variola virus, was a massive problem historically. It existed in the Western hemisphere for thousands of years (genetic evidence of smallpox has been found in Egyptian mummies from ≈1500 BCE, but it was probably around long before then), and it was introduced to the New World during the Columbian exchange, which had devastating consequences for indigenous populations (which were already suffering from colonialist violence, which made epidemics much worse than they already would've been). Historically, smallpox had a case fatality rate between 30-50%, and survivors were often left disfigured or permanently disabled (you've probably seen pictures of smallpox scars, but smallpox can also cause blindness and other complications). Importantly, smallpox only affects humans—it has no animal hosts—which is why it's one of the few infectious diseases to have been completely eradicated. As of May 8, 1980, it officially no longer exists outside of certain designated American and Russian laboratories. (There are, however, concerns that it could be used as a bioweapon, which is why the government still stockpiles smallpox vaccines and antivirals. I wrote my bioethics term paper on this exact issue, and incidentally, it's one of the major reasons why I believe that STEM majors should take ethics courses!)
There were two strains of variola virus: variola major and variola minor. Variola major was much more dangerous, with a much higher mortality rate; variola minor typically didn't cause severe disease. Fortunately, infection with one strain conferred immunity against the other. Both strains are now eradicated. (People sometimes confuse variola minor with other viruses like cowpox and horsepox, but they're different things.)
There were four clinical forms of smallpox: ordinary (classic smallpox, associated with the rash you usually see in pictures), modified (less severe, often occurred in vaccinated people who got infected anyway), malignant (caused a flat rash instead of the usual pustules, associated with immune dysfunction, almost always fatal), and hemorrhagic (caused severe bleeding, and also near-universally fatal.) All of the non-ordinary forms could be difficult to diagnose because they looked so different from typical smallpox. The less serious "modified" form was often confused with chickenpox, and the hemorrhagic form was sometimes assumed to be a completely different disease. Occasionally, historical sources will refer to hemorrhagic smallpox as "black pox," with or without an understanding that it's caused by the same virus as ordinary smallpox.
Other relevant viruses:
Cowpox, caused by cowpox virus (an orthopoxvirus similar to smallpox) causes mild disease in cows, humans, and several other animals. Infection with cowpox virus confers immunity to variola—Edward Jenner noticed this relationship and used material from cowpox lesions to inoculate people against smallpox.
Vaccinia virus, another orthopoxvirus, is the source of the modern smallpox vaccine. It's closely related to both cowpox and horsepox (weirdly, it's actually closer to horsepox), but it's distinct enough to be its own species. Infection usually causes mild symptoms, and, of course, confers immunity to smallpox.
Chickenpox is an entirely different thing. It's caused by the varicella-zoster virus, which is a herpesvirus, not a poxvirus at all! Infection with varicella-zoster does not confer immunity to smallpox or any other poxvirus—chickenpox is from a totally different family.
So why are the names so weird and confusing? Why is everything about all of this so weird and confusing?
There are multiple reasons for this, so bear with me.
Historically, a "pox" was any disease that caused a bumpy rash of pustles/blisters. Chickenpox, smallpox, and the other "poxes" all cause superficially similar rashes—thus the similar names. (Even though we know now that chickenpox comes from a completely different family, this wouldn't have been apparent before the dawn of modern medicine.)
Smallpox was given that name to differentiate it from syphilis, which was known as the "great pox" when it first appeared in Europe. (Fun[?] microbiology fact: There are debates about the origins of syphilis, but the most common theory holds that it originated in the New World, and Christopher Columbus brought it back to Spain. In that way, it's kind of the inverse of smallpox.) Historically, smallpox was also known by a variety of other names in different European, Asian, and African cultures. Again, this gets murky, because historical physicians sometimes struggled to distinguish between similar-looking-but-different diseases.
Other poxviruses are often named after the animals in which they were first identified. This is not a hard-and-fast rule, though, and it can sometimes be misleading (for example, monkeypox virus was first discovered in laboratory monkeys, but it more often affects rodents and other small mammals. The disease formerly known as "monkeypox" was recently renamed "mpox" because the name wasn't accurate.) Also, some poxviruses aren't named after animals at all! It's a weird and inconsistent system (but a lot of virus names are kinda weird and inconsistent).
Related to the above: We don't even know where the name "chickenpox" comes from. I mean, we know it was called a "pox" because it causes a pox-y rash, but we don't know where the "chicken" part originated. There are multiple theories about this, none of which are definitive. The disease itself has nothing to do with chickens.
Basically, a lot of the weirdness is a result of historical naming practices—people identified and named these diseases before modern virology existed, and those names stuck, so now we have similar names for superficially-similar-but-ultimately-different viruses, and names whose origins have been completely lost to time. Later, virologists muddied the waters further by naming newly-discovered poxviruses after the animals in which they were first seen, even when these animals aren't natural hosts or reservoirs of those viruses. It's a mess! And, again, all of this is complicated by the fact that some of these diseases were very hard to diagnose (or distinguish from one another) before modern medicine existed. Now, we can sequence viral DNA and figure out what's actually going on—which viruses caused which symptoms, whether those viruses were closely related, and whether being infected with one disease conferred immunity to another—but historical doctors and scientists didn't have those tools, so they were doing they best they could with very limited information, and that led to a lot of weirdness in terms of how these viruses were named and classified. Our current system inherited some of that weirdness, so here we are.
TL;DR: Poxvirus names are messy. Smallpox is caused by variola virus, which has two strains: variola major (the more severe one) and variola minor (less severe). Cowpox and vaccinia are different viruses in the same family, and being infected with one of them confers immunity to smallpox. Chickenpox isn't a poxvirus at all, but a herpesvirus—it just happens to cause a pockmark-y rash that looks superficially similar to smallpox pustules (and mild forms of smallpox were historically confused with chickenpox).
(P.S. none of this is super relevant to the average person, so don't feel bad if you didn't know any of it. Unless you are a history major inventing new conspiracies about smallpox, in which case you definitely should feel bad.)
Sources & further reading under the cut!
Edward Jenner and the history of smallpox and vaccination
The History of Smallpox (CDC)
The Triumph of Science: The Incredible Story of Smallpox Eradication
Scientific Background on Smallpox and Smallpox Vaccination (from Scientific and Policy Considerations in Developing Smallpox Vaccination Options: A Workshop Report) <- this article is like 20 years old, but it has some interesting information about the clinical forms of smallpox and how difficult they would be to diagnose accurately
Phasing out monkeypox: mpox is the new name for an old disease <- discusses the renaming of monkeypox to mpox, also mentions issues with other poxvirus names and virus names in general
Poxes great and small: The stories behind their names
being the second child is so lame when your older brother has no fortunes to inherit or power to come into. all of my scheming younger brother tendencies are being completely wasted like it’s not even worth putting all my efforts into usurping him and taking his place as heir. it’s not even worth it
like obviously I’m still going to do it because plotting and scheming are natural responses to being the second child but it’s just not the most lucrative career option anymore
the funniest part of this post to me is that the reblog:like ratio is nearly 1:1. nobody’s just liking everyone who sees this video goes yeah i gotta inflict it on as many people as possible
True Statement: "When you have a hammer, everything looks like a nail."
Truer Statement: "When you mixed too much two-part epoxy that's rapidly setting and you have 300 blank pin backs burning a hole in your craft drawer, everything in your house looks like it might make a cool pin."
The recent hot VS cold polls have made me realise that a lot of people have no idea how to cool down.
As someone from a hot country that's regularly on fire, here's some tips:
WATER IS YOUR FRIEND! WATER! IS! YOUR! FRIEND! You can transfer SO much heat into this bad boy! You cannot cool down without water!
Wrists under the cold tap. Splash your face and the back of your neck. Fan yourself.
In some countries you can buy a little handeld fan with a water sprayer.
Damp tea towel around the neck. Stick an ice pack in there on hotter days.
Half fill a water bottle with water, stick in freezer. If you use a bottle with a straw, make sure it's lying on its side with the straw side up and out of the water. When frozen top up the rest of the way with tap water and off you go.
Desperate to cool off? Wet T-shirt. Sit in front of a fan. This will nuke it, just don't get hypothermia and don't fall asleep like this.
Cold showers are also your friend in summer. Some people get psyched up by these. Personally, I sleep like a baby, so I'm good to have them before bed. Just keep in mind that it takes a bit of time for the cool to circulate, so your body will tell you that you're colder than you actually are. I find that when I have cold showers I need to step out of the spray when I think I'm cold... I'll just wait, and thirty seconds later the temperature has evened out and I actually need to step under again. Rinse and repeat until you maintain coolness even after stepping out for a bit.
If you can't do cold showers, turn the cold shower on anyway and just stick your arms under. When they're cold, lift your arms up above your head. The sensation of cool blood draining into your body is fucking weird and kinda unpleasant but less unpleasant than being hot.
Feet in a tub of water with ice. Blood naturally flows to your extremities when hot, so take advantage of this. If you don't have a tub of ice water, sticking a wet rag on your feet in front of the fan works too, it's the less powerful version of the wet T-shirt.
Drinks lots of water but make sure that water has electrolytes as well. Stay in the shade.
Keep air circulating. Fans don't actually cool rooms down, they just help transfer heat from your body to the moisture on your skin or the air via evaporative cooling.
Block north facing windows early in the morning so the sun doesn't get in. If you're in the northern hemisphere, this is opposite for you. Keep in mind that if your home is brick, the bricks will still heat up and slowly release heat into your home even after the sun goes down so this will only do so much.
If it's hotter inside than outside, close all your windows but two, making sure they're on opposite sides of the house/unit you're in. Point a fan out of one window, making sure that the doors between the rooms with the open windows are all open. This will help create a mini pressure system in your home, pulling cooler air in and pushing the hotter air out via the fan. Bonus points if you can get that fan high up where the hot air rises; even within a single room the top is much hotter than the air by the floor. Adjust the amount of open windows based on how many fans you have, but generally you want more windows with fans open than windows without fans to keep the pressure correct.
Obviously, use your common sense for these. Not everything WILL work for you, just use the stuff that does and adjust what needs to be adjusted. Some of these will be impossible to use in the workplace but others you can still use. Others are best used at home. If humidity impacts your ability to use any of these, get a dehumidifier if that's an option, or use more ice instead of evaporation.
Also keep in mind that the skinnier you are, the faster these will work. More fat means more insulation, means more heat, so you may need to be more patient with some of these or use them in combination.
Or soak a baseball cap or other cloth hat that won’t be damaged by water.
Water needs energy to evaporate. As it dries, it consumes a little heat in its immediate vicinity.
Therefore any significant amount of water — buckets, wet towels, damp laundry— in a small room can cool it a degree or two, although this doesn’t work as well if the air is already humid.
This principle has been used since ancient times, from wet blankets hung over doors in ancient Egypt to the “swamp coolers” of the southern U.S. before modern AC, to modern “evaporative coolers.” And, of course, it’s the function of sweat.
You gotta read and watch some old books and films that aren’t 100% modern politically correct. I’m not saying you should agree with everything in them but you need to learn where genres came from to understand what those genres are doing today and where media deconstructing old tropes is coming from.
Also, more often than you might think, they’re not actually promoting bigotry so much as “didn’t consider all the implications of something” or just used words that were polite then but considered offensive now.
When we choose to avoid history because it's Problematic or Says Bad Things, we are choosing to divorce ourselves from understanding how we came from that time to this one, which makes it even more likely for the cycle to repeat, with no one but a few people with shelves of old books aware that it's happened before.
and this shit's important. Media from the past tells us how people from the past acted and thought and behaved.
Plus, a lot of these media pieces were socially acceptable and/or progressive for their time. For example, The Adventures of Huckleberry Finn, while it contains a lot of words and ideas that are offensive now, was very progressive for its time. The book is a statement piece for how a young man who's grown up in a racist environment, with no words to explain himself other than racist and bigoted ones, decides that the whole system is shit and he's not going to follow those rules any more. So not reading or engaging with it because it uses the n-word a lot really misses the point.
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