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BALINTORE CASTLE - SCOTLAND

the "came back wrong" trope except like... they didnt. like this mad scientists wife died, and so he studied necromancy, brought her back, and she came back and it all worked. like she came back exactly the same as she was before with literally no difference. but the scientist guy is like "oh no... what have i done.... shes Different now!!!! she came back Wrong!!!!" and shes just like. chilling. reading a book. cooking dinner. shes just so so normal but in the guys mind hes like "oh shes soooo weird" but shes just normal

mysticorset

Peer reviewed tags from @somanyofthekids

notahorseindisguise

NO its a JOKE and YOU DONT GET IT. ITS NOT THAT DEEP

hiveswap

While she was dead he put his memory of her on such a high pedestal that she could never live up to it alive

midnight-revolucion

alternatively‚ she came back perfectly fine but he thinks she came back wrong‚ because the tragic reality is that he never actually knew his wife

notahorseindisguise

im going INSANE thats MY POST.

marlinspirkhall

It's your post but the journey to posting it changed it to such a degree that even its closest intimacies are now foreign to you. Sorry dude.

beemovieerotica

the cognitive dissonance from people who want the products of modern medicine but get weird about animal research. like im sorry but this is necessary for the survival of the society we currently live in. and the scientists who work on these things are not evil cackling psychopaths. anyone you talk to in animal research has incredibly complex feelings about their work and incredibly complex relationships to the animals in their care. there are regulations and oversight and penalties in place to make the work as humane as possible and scientists are overwhelmingly the ones enforcing and advocating for better care.

beemovieerotica

@velvetdemon I'm doing a full reply because I want to give this question the time and space it deserves, and I really do appreciate your curiosity about this.

The short answer: It is deeply unethical. There are nowhere near enough willing patients in the world to be able to do this, and it would be criminal to put them through this.

The long answer: The one side of the equation you're focusing on is: how much of a drug is too much, to the point where it will cause negative side effects or even death? And this is crucial to know. But it's not just a matter of finding out the lethal dosage of a heart cholesterol medication, you need to know that it can actually lower the cholesterol of any living thing. There is no way to know this without giving it first to...a living thing.

But beyond this, I need to emphasize: The goal of a drug trial is to effectively cure people who are already suffering from disease, who are living on limited time.

Drug trials don't just happen on any member of the public, they need to happen specifically on people affected by the disease you're trying to treat. There is at any time a very limited and very marginalized population of the world affected by early onset, familial Parkinson's disease. Because you cannot ethically induce disease in a human being, you are working with, speaking with, and helping patients and their families who are hopeful and desperate for a cure.

If you were to jump straight to human trials from petri dishes, not knowing absolutely anything about how the drug functions in a living, breathing animal body, it would look like this:

We didn't know that minute quantities of the drug interact lethally with x, y, z medication that people are commonly also taking. X number of patients have died as a result.

We didn't know that the drug is fatal to people with [common variant] in their genetics. X more patients have died.

We didn't know the drug exacerbates x, y, z chronic illnesses. X number of people have acquired permanent, lifelong disabilities.

We didn't know the best way to deliver the drug, so we tried multiple ways: the people who received it intravenously are now suffering from a painful, costly, and debilitating condition that did not happen with the ingested form.

I could go on, and on, and on.

The vast majority of these problems can be nearly or almost entirely averted by testing other animals first.

These are all people who possibly could have waited for the normal progression from animal testing to human testing and thus received better outcomes. Some people will pass away in the time it takes to get to that point, and that's heartbreaking, and we all wish science could be faster.

But the cost of expediting science could mean a life of profoundly greater suffering or an even shorter life than the one where no intervention happens at all. And at that point, you have completely exhausted your trust, your goodwill, and your patients' hope, after you've failed to do anything or even worsened the lives of people who are already deeply suffering.

manslaughter

hi, i’m an animal research professional. making sure laboratory animals stay alive, healthy, and enriched has been my full-time job for several years now.

animal research is not the mad scientist wild west that PETA wants you to think it is. there are extremely strict federal laws in place to protect the well being of these animals. animal welfare organizations like AAALAC ensure that lab animals are treated with dignity & respect and are given enough specialized care & enrichment to be happy and content in captivity, just like AZA accreditation with zoos.

not a single animal from a zebrafish to a mouse to a dog to a macaque goes unaccounted for. if an animal gets moved to a new cage, paired for breeding, has a procedure performed on it, gives birth, gets sick or injured, dies, etc. it is legally required that this information is recorded and kept on file for the US federal government to access. failing to record & retain this information is very much punishable by US federal law.

let me tell you - if you abuse or kill an animal, even a mouse - you are almost certainly getting both fired & blacklisted from the industry. if you abuse or kill a more ‘advanced’ animal, such as a dog or monkey, you will likely face criminal charges. killing a monkey is as serious and disastrous as a nuclear meltdown. you are expected to reasonably explain every illness, injury, or death of an animal under your care. you must record all of this information. animals that are clearly suffering with low QOL are required to be euthanized according to AVMA guidelines.

research animals are highly expensive. yes, even the "lesser" animals like mice. the cheapest mice will run you a few hundred $ per individual, with some of the most expensive mice i've cared for being $25,000 per individual. in research we have the "three Rs" - reduction (reduce amount of necessary animals to a minimum), refinement (refine processes to ensure research is accurate and animals feel no pain or distress), and replacement (replace animals with non-living research models as they become available). i can assure you no proper research team is wasting animals (*do not* say "b-b-but elon musk--" his research team is actively being investigated for animal abuse by the government).

research methods that do not require live animals are currently being looked into & efforts spearheaded by - you guessed it - the animal research industry itself (notice how the animal rights people are strangely silent & unhelpful when it comes to this?) but current technology is rudimentary and does not compare to live animal models.

some research animal fun facts (US edition):

all species of animals are only allowed to have one single major surgery performed on them in their entire lifetime.

institutions with nonhuman primates must have a behavior program in place (run by knowledgeable primate specialists) to ensure that they are happy and receiving enough daily enrichment and social interaction.

institutions with dogs are required to have physical exercise programs in place. this means every individual dog gets a substantial amount of leashed AND free-roaming exercise daily, including playgroups with other dogs.

a majority of nonhuman primates get to retire to sanctuaries like peaceable primate sanctuary, and almost all dogs get retired and adopted out by organizations like homes for animal heroes. some institutions will also adopt out unneeded young rabbits, guinea pigs, rats, etc.

some strains of mice glow neon green (or orange or blue) under UV light. this is not harmful to them and is commonly seen in cancer research.

so yes, you can rest knowing that laboratory animals are treated with the utmost respect by their caretakers. and you can stop this awful, ignorant talk of human experimentation that will only end in the abuse of nonwhite people, LGBT people, disabled people, indigenous people, and so many others. please just take a look at this wikipedia page if you think “ethical” human experimentation can exist.

boffin-in-training-deactivated2

One of the biggest ways to eliminate waste of life is to challenge intellectual property, for profit medicine and ultimately capitalism and borders. Competition in developing medicine is one of many avoidable wastes of lab animal life. Competition among cosmetic companies as well.

huehxolotl

If you see this, you are legally obligated to take a nappy nap

amygdalae

Keying/graffiti-ing someones car is old news now if someone cheats we go at their wardrobe with a seam ripper

yknow what? Fuck you *unstitches all your shirts and jeans*

melyzard

My mother did this to my father once. They got into an argument, my very pregnant and hormonal mother stormed off…except they lived in a tiny apartment so the only place to go was to shut herself into the closet for a good long sulk. And while she was sitting in there, fuming, she looked up and saw her sewing kit on the shelf, and all my father’s uniforms hanging right there.

So she picked one shirt and one pair of trousers, carefully, methodically ripped every third stitch out of every seam, and then hung them back up together so that he would be likely to pick them at the same time. This took her a couple hours, so by the time she was done, the anger had worn down. She came out, she and my father had a talk that ended in apologies, after which they were tired and went to bed. My mother swears up and down that she meant to warn my father about the sabotaged clothes in the morning, but he wore a different uniform set and they were both still feeling a little raw, so she didn’t want to bring up the fight again. She decided to tell him that night instead.

And then she forgot.

Anyway, about four days later, my father apparently came home roughly an hour after he left for work, his clothes slowly, gently shredding off his body, the most bewildered expression on his face. “Paula,” he said, his voice mildly shell-shocked. “Paula, my clothes are broken.”

My mother promptly burst out laughing so hard that she went into labor. And that’s the story of my birth, heralded by petty vengeance and utter confusion.

papayajuan2019

this is one of my favorite english words. and what i aim to become.

onegingek

A king exists for his people. Without his people, there can be no king.

electronicgallery

It appears that boredom lies behind the most creative ideas. That's why quarantine has produced some of the most entertaining activities. One of them is the Getty Museum challenge, that so many of you have already seen in our previous article here.

delphinidin4

Narcissus taking a selfie is the ACTUAL best.

simplyclockwork

These are REALLY cool

notallfay

These are art in themselves, in a some of them point out what lockdown was like for us, they’re expressed themselves in a really cool way. But I think these are going to be talked about in the future.

kaijuno

[kicks down door] HEY COSPLAYERS

Cosplayer Artemisia Moltabocca has pulled together an extensive resource of free sewing patterns for historical costumes, all available onli

chronicdharma

cervinelich

this is why its depressing to work in a pharmacy.

iatrogenic

I was definitely a profit killer when I worked in a pharmacy (which honestly was my favorite job in the entire world, but it was short-lived and nowadays you can’t work at a pharmacy like that, it’s all tied in with corporate retail and no one should ever trust me with a cash register ever). It was not, however, actually a profit killer for the pharmacy, just for the drug companies, so no one cared. These days I do medical billing, which means I actually bill OUT from hospitals so I’m mostly spending my professional time taking money away from insurance companies.

I will now impart all of my profit killing resources onto you, in case you don’t know them. I think most of you know them, now. But just in case you don’t.

THIS IS US-CENTRIC. I’M SORRY.

1. GoodRx - this thing has an app now, so you can look up the best places to get your expensive medicines at the lowest possible prices without insurance on the go, and you no longer have to print coupons because you can just hand over your phone or tablet. Times have changed for the better with GoodRx. Definitely use it before trying to fill your scrip, because it will tell you the best place to go. (You can do that on the website, too.)

2. NeedyMeds - Needymeds is basically the clearinghouse of drug payment assistance. They have their own discount cards, but also connections to many patient assistance programs run by drug companies themselves. They are good assistance programs, too.

3. Ask your county - This is not a link. This is a pro tip. Most county social services will have pharmacy discount programs for people with no and/or shitty pharmaceutical coverage. You can often just find them hanging around at social services offices; you can just pick one up and walk off with it.

4. Ordering online - There are a few safe online pharmacies. I keep a little database in a text file on my computer. Most of them are courtesy of CFS forums, my mother or voidbat, so a lot of that is a hat tip to other people, but if you’re in need of a place to get a drug without a prescription … first I’ll make sure you 100% know what you’re doing for safety reasons and then I’m happy to turn over a link.

5. Healthfinder - A government resource that helps find patient assistance programs in your area. This might also point out the convenient county card thing. RxHope is something a lot of people get pointed to via Healthfinder that’s a good program.

6. Mental Health America - Keeps a list of their best PAPs for psychiatric medications, which can be some of the most expensive and a lot of pharmacy plans don’t cover them at all.

forevrdreamingofbetterthings

This is so important ppl.

Signal boost the shit out of it!

dynastylnoire

Booooooooooooooooooost

dysfunctionalqueer

Good Rx Saved my family a hundred dollars a month while I was getting signed up for CHIP seriously it’s a life savor especially for ridiculously expensive drugs like abilify

motivation-gems

Useful info, friends! ;)

quietborderlineinfo

Since many of our followers are on medications, I feel like this would be an important resource. -Luna

will-work-for-spoons

Also! Some drug companies have patient assistance programs where they send you the drug for FREE if you are uninsured, or if your insurance doesn’t cover that drug.

Do a Google search for “patient assistant programs” + (your med), or search the manufacturers website. Sometimes the info is online; other times you have to call.

Even some of the big name pharma companies have this. It’s certainly not all companies, or all meds, but it is worth a shot.

Before Obamacare, I lost insurance and couldn’t pay for my mood stabilizers (kiiiiinda important to have those when you’re bipolar.) I was on generic Lamictal, but I went to the official Lamictal website, filled out a form with a valid prescription, and they mailed my meds to me every month for free.

If you know anything about bipolar disease, you know that that was a literal life saver. Patient assistance programs ftw!

comtessedebussy

This is so important given the recent vote to repeal Obamacare. And the cartoon above is so on point They’re literally voting to kill people. Literally.

thebibliosphere

Some of my meds are no longer going to be partially covered by my ridiculously expensive private insurance. I just used the GoodRX website to look it up, and I can either spend $40 at Target to pay for one of them out of pocket–per month–, or I can get it at Sams Club for $4. No that is not a typo. The drug I need to take every single day to keep my allergies from spiraling out of control (yay auto-immune bullshit) is literally ten times cheaper at Sams Club. Holy shit.

fancyladssnacks

Signal boost for my US buds

puraiuddo

I was also a profit killer at CVS, until they banned the employees from providing any discount codes and threw away all of our discount cards and then told us that all we were allowed to do was to tell customers that they could look for their own. ☺️

They were especially adamant about enforcing this new policy at my store which was: (1) the only 24hr pharmacy within 20 miles (2) geographically right between 2 popular ERs (3) criminally understaffed (4) at the center of a notoriously Portuguese city and (5) had minimal, if any, translators to communicate to the populace that they could find discount cards.

CVS is also well known on the above mentioned apps for being the most expensive place to buy uninsured medicine.

Needless to say, I quit.

DON’T USE CVS AND PLEASE USE DISCOUNT CARDS.

rapidashrider

“I’m like, ‘Okay, she’s a doll. She’s a plastic doll. She doesn’t have organs. If she doesn’t have organs, she doesn’t have reproductive organs. If she doesn’t have reproductive organs, would she even feel sexual desire?’ No, I don’t think she could,” Robbie said. “She is sexualized. But she should never be sexy. People can project sex onto her. Yes, she can wear a short skirt, but because it’s fun and pink. Not because she wanted you to see her butt.”

Margot Robbie said Ace Barbie Rights with her whole chest.

double-o-donut

some underappreciated vines i haven’t seen in any vine compilation yet i that found way deep in my vines tag

mikkeneko

i mean it quite seriously when i say that i mourn vine… but i think its existence taught an entire generation of people about drama, cinemetography and comedy

xaveria

noticed my coworker was on tumblr so i told them “i like your shoelaces” and they said “never say that out loud to me”

xaveria

this is the correct response btw

mrspockomakeitso

When I read “space...the final frontier” there’s a small part of my brain that is that audio of Patrick Stewart saying it but with a ridiculous french accent that makes it “eh-spay-zeh...ze final frahn-tee-aire” while Jonathan Frakes absolutely loses it in the background.

plaguedoctorsnake

https://youtu.be/VV10in63_Ok can’t stop laughing at this

scubastranaut

oh my GOD

animentality

heywriters

Using tumblr is like living in a low class apartment building. You just get used to the landlord not fixing things, and then someone new moves in and you’re helpfully like “oh yeah don’t drink the tap water, it’s got stuff in it that makes you sick” and then your neighbor you’ve had forever goes “oh they took the stuff out actually” and you’re like “what? when was this?”

“like two years ago”

“you mean i could’ve been drinking the tap water all this time?”

“yeah. they gave us individual mailboxes too finally, you don’t have to dig through the communal bin anymore”

“are you for real right now?? i just redirected my mail, i didnt know”

and the new tennant is like “why did you guys even live here if it was so bad”

“we like it.”

“I kinda miss the communal mail bin tho”

heywriters

“the perpetually naked guy got evicted though”

“i know, so sad. he was really gross”

“i mean, his cousin streaks through the commons sometimes and knocks on all the doors”

“oh yeah, hate that guy”

aniseandspearmint

New Person: I just saw this weird guy in the lobby in a really creepy anthropomorphic Pikachu costume??????

Old Resident: yeah we have no idea where that guy came from. We’ve left messages with maintenance ‘bout ‘im but-

Other Old Resident: just don’t make eye contact and you should be fine.

sometimesdesperate

“what are these strange markings in the paint?”

“Oh! Thats from the crab infestation!”

“The crab infestation?! Wow, glad they got that under control before I moved in.”

“Oh, no no, it was an intentional infestation.”

“Uh….”

“Yeah, we’re hoping they bring the crabs back next year. A lot of us made friends with those crabs.”

paperpalooka

No, I’m not joking, he doesnt just look like him, I swear to God neil gaiman lives across the hall.

warrior-kitty

The apartment building throws holiday parties but not typical parties like for Christmas or Valentine’s day

Knives are decorating the walls for the Ides Of March.

There’s a community movie night held on October 3rd where tenants choose to watch either Mean Girls or binge watch all of Fullmetal Alchemist.

Every single apartment opens their windows and blasts Earth, Wind, and Fire on the 21st of September

November 5th rolls around and the entire building just erupts into inexplicable chaos

spiderine

“What’s with the floor?”

“Color theory. Don’t worry about it.”

mister-christmas

“Why is the cemetery across the street partially dug up?”

“Ah, yeah, there was a problem with grave robbing witches a while back.”

wilwheaton

“Why do you do [totally normal thing] this way?” “Oh, [totally confusing and illogical system] is how we’ve always done it. “You think we call it a Hellsite for fun?”

prideknights

Ace of Spades

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